Retrovirally expressed metal response element-binding transcription factor-1 normalizes metallothionein-1 gene expression and protects cells against zinc, but not cadmium, toxicity

Toxicology and Applied Pharmacology

Volumn 178, Issue 2, 2002, Pages 93-101

  Solis, Willy A ^a   Childs, Nicole L ^a   Weedon, Michael N ^a   He, Lei ^a   Nebert, Daniel W ^a   Dalton, Timothy P ^a  

^a UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

Author keywords

Cadmium; Gene expression; Metal response element (MRE); Metal toxicity; Metallothionein; MRE binding transcription factor 1 (MTF1); Oxidative stress; Retroviral transduction; Transcriptional regulation; Zinc

Indexed keywords

CADMIUM; METAL RESPONSE ELEMENT BINDING TRANSCRIPTION FACTOR 1; METALLOTHIONEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZINC;

ANIMAL CELL; ARTICLE; CELL PROTECTION; CHROMATIN; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; GENE CONTROL; GENE EXPRESSION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN MOTIF; RETROVIRUS; TRANSCRIPTION REGULATION;

MAMMALIA;

EID: 0037081562     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.2001.9319     Document Type: Article

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