Disseminated intravascular coagulation: Clinical and laboratory aspects

American Journal of Hematology

Volumn 59, Issue 1, 1998, Pages 65-73

  Carey, Michael J ^a   Rodgers, George M ^a,b,c  

^a UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c ARUP LABORATORIES   (United States)

Author keywords

Bleeding disorders; DIC; Hemostasis; Tissue factor

Indexed keywords

ACTIVATED PROTEIN C; ALPHA 1 ANTITRYPSIN; AMINOCAPROIC ACID; ANTICOAGULANT AGENT; ANTIFIBRINOLYTIC AGENT; ANTITHROMBIN III; APROTININ; DITHIOCARBAMIC ACID; GABEXATE; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; PENTOXIFYLLINE; THROMBIN INHIBITOR; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; THROMBOMODULIN; THROMBOPLASTIN; TRANEXAMIC ACID;

ANIMAL MODEL; ANTICOAGULANT THERAPY; BLEEDING DISORDER; CLINICAL TRIAL; DIAGNOSTIC TEST; DISSEMINATED INTRAVASCULAR CLOTTING; HEMATOLOGICAL PARAMETERS; HUMAN; LABORATORY DIAGNOSIS; MULTICENTER STUDY; NONHUMAN; PRACTICE GUIDELINE; PRIORITY JOURNAL; REVIEW; TREATMENT INDICATION;

DISSEMINATED INTRAVASCULAR COAGULATION; HUMANS;

EID: 0031822215     PISSN: 03618609     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8652(199809)59:1<65::AID-AJH13>3.0.CO;2-0     Document Type: Review

References (67)

1. Rodgers GM: Hemostatic properties of normal and perturbed vascular cells. FASEB J 2:116-123, 1988.
2. Rapaport SI: The extrinsic pathway inhibitor: A regulator of tissue factor-dependent blood coagulation. Thromb Haemost 66:6-15, 1991.
3. Baglin T: Disseminated intravascular coagulation: Diagnosis and treatment. BMJ 312:683-687, 1996.
4. Colucci M, Balconi G, Lorenzet R, Pietra A, Locati D, Donati MB, Semeraro N: Cultured human endothelial cells generate tissue factor in response to endotoxin. J Clin Invest 71:1893-1896, 1983.
5. Drake TA, Cheng J, Chang A, Taylor FB: Expression of tissue factor, thrombomodulin, and E-selectin in baboons with lethal Escherichia coli sepsis. Am J Pathol 142:1458-1470, 1993.
6. More L, Sim R, Hudson M, Phillon AP, Pounder R, Wakefield AJ: Immunohistochemical study of tissue factor expression in normal intestine and idiopathic inflammatory bowel disease. J Clin Pathol 46: 703-708, 1993.
7. Gralnick HR, Abrell E: Studies on the procoagulant and fibrinolytic activity of promyelocytes in acute promyelocytic leukemia. Br J Haematol 24:89-99, 1973.
8. Callander N, Rapaport SI: Trousseau's syndrome. West J Med 158: 364-371, 1993.
9. Jacobson RJ, Jackson DP: Erythrocyte fragmentation in defibrination syndromes. Ann Intern Med 81:207-209, 1974.
10. Wada H, Tanigawa M, Wakita Y, Nakase T, Minamika K, Kaneko T, Ohiwa M, Kageyama S, Kobayashi T, Noguchi T: Increased plasma level of interleukin-6 in disseminated intravascular coagulation. Blood Coag Fibrinol 4:583-590, 1993.
11. Mayeux PR: Pathobiology of lipopolysaccharide. J Toxicol Env Health 51:415-435, 1997.
12. Dinarello CA: The proinflammatory cytokines interleukin-1 and tumor necrosis factor and treatment of the septic shock syndrome. J Infect Dis 163:1177-1184, 1991.
13. Damas P, Canivet JL, de Groote D, Yrindts Y, Albert A, Franchimont P, Lamy MM: Sepsis and serum cytokine concentrations. Crit Care Med 25:405-412, 1997.
14. Okajima K, Uchiba M, Murakami K, Okabe H, Takatsuki K: Plasma levels of soluble E-selectin in patients with disseminated intravascular coagulation. Am J Hematol 54:219-224, 1997.
15. Carr JM, McKinney M, McDonagh J: Diagnosis of disseminated intravascular coagulation: Role of D-dimer. Am J Clin Pathol 91:280-287, 1989.
16. Bick RL, Baker WF: Diagnostic efficacy of the D-dimer assay in disseminated intravascular coagulation (DIC). Thromb Res 65:785-790, 1992.
17. Bick RL: Disseminated intravascular coagulation. Objective criteria for diagnosis and management. Med Clin North Am 78:511-543, 1994.
18. Faulkner WR: Laboratory diagnosis of DIC. Lab Rep 17:1-5, 1995.
19. van de Water L, Carr JM, Aronson D, McDonagh J: Analysis of elevated fibrin(ogen) degradation product levels in patients with liver disease. Blood 67:1468-1473, 1986.
20. Asakura H, Kamikubo Y, Goto A, Shiratori Y, Yamazaki M, Jokaji H, Saito M, Uotani C, Kumabashiri I, Morishita E, Aoshima K, Nakamura S, Matsuda T: Role of tissue factor in disseminated intravascular coagulation. Thromb Res 80:217-224, 1995.
21. Takahashi H, Sato N, Shibata A: Plasma tissue factor pathway inhibitor in disseminated intravascular coagulation: Comparison of its behavior with plasma tissue factor. Thromb Res 80:339-348, 1995.
22. Wada H, Wakita Y, Nakase T, Shimura M, Hiyogama K, Nagaya S, Deguchi H, Mori Y, Kaneko T, Deguchi K, Fujii J, Shiku H: Increased plasma-soluble fibrin monomer levels in patients with disseminated intravascular coagulation. Am J Hematol 51:255-260, 1996.
23. Kunishima S, Kobayashi S, Naoe T: Increased but highly dispersed levels of plasma glycocalicin in patients with disseminated intravascular coagulation. Eur J Haematol 56:173-177, 1996.
24. Ono S, Mochizuki H, Tamakuma S: A clinical study on the significance of platelet-activating factor in the pathophysiology of septic disseminated intravascular coagulation in surgery. Am J Surg 171: 409-415, 1996.
25. Wada H, Minamikawa K, Wakita Y, Nakase T, Kaneko T, Ohiwa M, Tamaki S, Deguchi A, Mori Y, Deguchi K, Shirakawa S, Suzuki K: Hemostatic study before onset of disseminated intravascular coagulation. Am J Hematol 43:190-194, 1993.
26. Grosset ABM, Rodgers GM: Acquired coagulation disorders. In GR Lee, J Foerster, J Green, GM Rodgers, F Paraskevas, JN Lukens (eds): "Wintrobe's Clinical Hematology," Ed 10. Baltimore: Williams & Wilkins, 1998.
27. Ballard HS, Marcus AJ: Platelet aggregation in portal cirrhosis. Arch Intern Med 136:316-319, 1976.
28. Fletcher AP, Alkjaersig N, Fisher S, Sherry S: The proteolysis of fibrinogen by plasmin: The identification of thrombin-clottable fibrinogen derivatives which polymerize abnormally. J Lab Clin Med 68:780-802, 1966.
29. Humphries JE: Transfusion therapy in acquired coagulopathies. Hematol Oncol Clin North Am 8:1181-1201, 1994.
30. Ness PM, Perkins HA: Cryoprecipitate as a reliable source of fibrinogen replacement. JAMA 241:1690-1691, 1979.
31. Pitney WR: Disseminated intravascular coagulation. Semin Hematol 8:65-83, 1971.
32. Sack GH, Levin J, Bell WR: Trousseau's syndrome and other manifestations of chronic disseminated coagulopathy in patients with neoplasms: Clinical, pathophysiologic, and therapeutic features. Medicine (Baltimore) 56:1-37, 1977.
33. Litt MR, Bell WR, Lepor HA: Disseminated intravascular coagulation in prostatic carcinoma reversed by ketoconazole. JAMA 258:1361-1362, 1987.
34. Martinez JFT, Redondo MDT, Silva IA, Lopez-Borrasca A: Disseminated intravascular coagulation in prostatic carcinoma reversed by antiandrogenic therapy. JAMA 260:2507, 1988.
35. Tallman MS, Kwaan HC: Reassessing the hemostatic disorder associated with acute promyelocytic leukemia. Blood 79:543-553, 1992.
36. Warrell RP, Frankel SR, Miller WH, Scheinberg DA, Itri LM, Hittelman WN, Vyas R, Andreeff M, Tafuri A, Jakubowski A, Gabrilove J, Gordon MS, Dmitrovsky E: Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid). N Engl J Med 324:1385-1393, 1991.
37. Corrigan JJ, Jordan CM: Heparin therapy in septicemia with disseminated intravascular coagulation. N Engl J Med 283:778-782, 1970.
38. Feinstein DI: Diagnosis and management of disseminated intravascular coagulation: The role of heparin therapy. Blood 60:284-287, 1982.
39. Gurewich V, Lipinski B: Case report: Low-dose intravenous heparin in the treatment of disseminated intravascular coagulation. Am J Med Sci 274:83-86, 1977.
40. Green D, Seeler RA, Allen N, Alavi IA: The role of heparin in the management of consumption coagulopathy. Med Clin North Am 56: 193-200, 1972.
41. Naeye RL: Thrombotic state after a hemorrhagic diathesis, a possible complication of therapy with epsilon-aminocaproic acid. Blood 19: 694-701, 1962.
42. Lechner K, Kyrle PA: Antithrombin III concentrates: Are they clinically useful? Thromb Haemost 73:340-348, 1995.
43. Kessler CM, Tang ZC, Jacobs HM, Szymanski LM: The suprapharmacologic dosing of antithrombin concentrate for Staphylococcus aureus-induced disseminated intravascular coagulation in guinea pigs: Substantial reduction in mortality and morbidity. Blood 89:4393-4401, 1997.
44. Fuse S, Tomita H, Yoshida M, Hori T, Igarashi C, Fujita S: High dose of intravenous antithrombin III without heparin in the treatment of disseminated intravascular coagulation and organ failure in four children. Am J Hematol 53:18-21, 1996.
45. Umeki S, Adachi M, Watanabe M, Yaji S, Soejima R: Gabexate as a therapy for disseminated intravascular coagulation. Arch Intern Med 148:1409-1412, 1988.
46. Okamura T, Niho Y, Itoga T, Chiba S, Miyake M, Kotsuru M, Saito H, Ichimaru M, Hara K, Takatsuki K, Tsuda K, Igata A, Tanaka K: Treatment of disseminated intravascular coagulation and its prodromal stage with gabaxate mesilate (FOY): A multi-center trial. Acta Haematol 90:120-124, 1993.
47. Svartholm E, Haglund U, Ljungberg J, Hedner U: Influence of aprotinin, a protease inhibitor, on porcine E. coli shock. Studies on coagulation, fibrinolytic and hemodynamic response. Acta Chir Scand 155: 7-13, 1989.
48. Slaughter TF, Greenberg CS: Antifibrinolytic drugs and perioperative hemostasis. Am J Hematol 56:32-36, 1997.
49. Sundt TM, Kouchoukos NT, Saffitz JE, Murphy SF, Wareing TH, Stahl DJ: Renal dysfunction and intravascular coagulation with aprotinin and hypothermie circulatory arrest. Ann Thorac Surg. 55:1418-1424, 1993.
50. Scott CF, Carrell RW, Glaser CB, Kueppers F, Lewis JH, Colman RW: Alpha-1-antitrypsin-Pittsburgh. A potent inhibitor of human plasma factor Xla, kallikrein, and factor XIIf. J Clin Invest 77:631-634, 1986.
51. 358 against arterial hypotension induced by factor XII fragment. J Clin Invest 80:582-585, 1987.
52. 1-antitrypsin Pittsburgh attenuates experimental gram-negative septicemia. Am J Pathol 130:418-426, 1988.
53. Taylor FB, Chang A, Ruf W, Morrissey JH, Hinshaw L, Catlett R, Blick K, Edgington TS: Lethal E. coli septic shock is prevented by blocking tissue factor with monoclonal antibody. Circ Shock 33:127-134, 1991.
54. Levi M, ten Cate H, Bauer KA, van der Poll T, Edgington TS, Büller HR, van Deventer SJH, Hack CE, ten Cate JW, Rosenberg RD: Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees. J Clin Invest 93:114-120, 1994.
55. Dackiw APB, McGilvray ID, Woodside M, Nathens AB, Marshall JC, Rotstein OD: Prevention of endotoxin-induced mortality by antitissue factor immunization. Arch Surg 131:1273-1278, 1996.
56. Bajaj MS, Bajaj SP: Tissue factor pathway inhibitor: potential therapeutic applications. Thromb Haemost 78:471-477, 1997.
57. Creasey AA, Chang ACK, Feigen L, Wun T-C, Taylor FB, Hinshaw LB: Tissue factor pathway inhibitor reduces mortality from Escherichia coli septic shock. J Clin Invest 91:2850-2860, 1993.
58. Park CT, Creasey AA, Wright SD: Tissue factor pathway inhibitor blocks cellular effects of endotoxin by binding to endotoxin and interfering with transfer to CD14. Blood 89:4268-4274, 1997.
59. Bohrer H, Qiu F, Zimmermann T, Zhang Y, Jllmer T, Männel D, Böttiger BW, Stern DM, Waldherr R, Saeger H-D, Ziegler R, Bierhans A, Martin E, Nawroth PP: Role of NFκB in the mortality of sepsis. J Clin Invest 100:972-985, 1997.
60. Schreck R, Meier B, Männel DN, Dröge W, Baeuerle PA: Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells. J Exp Med 175:1181-1194, 1992.
61. Orthner CL, Rodgers GM, Fitzgerald LA: Pyrrolidine dithiocarbamate abrogates tissue factor (TF) expression by endothelial cells: Evidence implicating nuclear factor-κB in TF induction by diverse agonists. Blood 86:436-443, 1995.
62. Drollinger AG, Netser JC, Rodgers GM: Dithiocarbamates ameliorate the effects of endotoxin in a rabbit model of disseminated intravascular coagulation (DIC). J Invest Med 46:78A, 1998.
63. Reisinger EC, Kern P, Ernst M, Bock P, Flad HD, Dietrich M, and German DTC Study Group: Inhibition of HIV progression by dithiocarb. Lancet 335:679-682, 1990.
64. Hersh EM, Brewton G, Abrams D, Bartlett J, Galpin J, Gill P, Gorter R, Gottlieb M, Jonikas JJ, Landesman S, Levine A, Marcel A, Petersen EA, Whiteside M, Zahradnik J, Negron C, Boutitie F, Caraux J, Dupuy J-M, Salmi LR: Ditiocarb sodium (diethyldithiocarbamate) therapy in patients with symptomatic HIV infection and AIDS. JAMA 265:1538-1544, 1991.
65. Taylor FB, Chang A, Esmon CT, D'Angelo A, Vigano-D'Angelo S, Blick KE: Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon. J Clin Invest 79:918-925, 1987.
66. Uchiba M, Okajima K, Murakami K, Johno M, Okabe H, Takatsuki K: Effect of human urinary thrombomodulin on endotoxin-induced intravascular coagulation and pulmonary vascular injury in rats. Am J Hematol 54:118-123, 1997.
67. Murakami K, Okajima K, Uchiba M, Johno M, Okabe H, Takatsuki K: A novel platelet activating factor antagonist, SM-12502, attenuates endotoxin-induced disseminated intravascular coagulation and acute pulmonary vascular injury by inhibiting TNF production in rats. Thromb Haemost 75:965-970, 1996.