Stabilization of breast cancer xenograft tumour neovasculature by angiopoietin-1

British Journal of Cancer

Volumn 86, Issue 4, 2002, Pages 645-651

  Tian, S ^a   Hayes, A J ^a   Metheny Barlow, L J ^a   Li, L Y ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Angiopoietin; Endothelial cells; Pericyte; Smooth muscle; Tumouc vasculature

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN RECEPTOR; RECEPTOR PROTEIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CELL STRAIN MCF 7; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; MESENCHYME CELL; MOUSE; NONHUMAN; PERICYTE; PRIORITY JOURNAL; STROMA; TUMOR GROWTH; TUMOR VASCULARIZATION; TUMOR XENOGRAFT; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASODILATATION;

ANGIOPOIETIN-1; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL DIVISION; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; MEMBRANE GLYCOPROTEINS; MICE; MICE, NUDE; MUSCLE, SMOOTH, VASCULAR; NEOVASCULARIZATION, PATHOLOGIC; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, TIE-2; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED; VASODILATION;

EID: 0037065969     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600082     Document Type: Article

References (46)

1. The effects of angiopoietin-1 and -2 on tumor growth and angiogenesis in human colon cancer
2. Expression of Tie1, Tie2, and angiopoietins 1, 2, and 4 in Kaposi's sarcoma and cutaneous angiosarcoma
3. Studies on blood capillaries. I. General organization of blood capillaries in muscle
4. Expression of angiogenesis stimulators and inhibitors in human thyroid tumors and correlation with clinical pathological features
5. Direct cell adhesion to the angiopoietins mediated by integrins
6. Angiogenesis in cancer and other diseases
7. Anglopoietin-1 is inversely related to thymidine phosphorylase expression in human breast cancer, indicating a role in vascular remodeling
8. Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning
9. The endothelial-specific receptor tyrosine kifiase, tek, is a member of a new subfamily of receptors
10. Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
11. Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: Concentration in tumor blood vessels
12. High-level expression of angiogenic factors is associated with advanced tumor stage in human neuroblastomas
13. Blood vessel formation: What is its molecular basis?
14. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
15. Tumor dormancy in vivo by prevention of neovascularization
16. Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: An index of cell proliferation with evidence of deregulated expression in some neoplasms
17. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
18. Angiopoietin-1 and its receptor tie-2 participate in the regulation of capillary-like tubule formation and survival of endothelial cells
19. Expression and function of angiopoietin-1 in breast cancer
20. Vascular endothelial growth factor in premenopausal, women - Indicator of the best time for breast cancer surgery?
21. Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF
22. Angiopoietin-1 induces sprouting angiogenesis in vitro
23. Analysis of Tie receptor tyrosine kinase in haemopoietic progenitor and leukaemia cells
24. The fetal vascularisation of term human placental villi. I. Peripheral stem villi
25. Distinct rat genes with related profiles of expression define a TIE receptor tyrosine kinase family
26. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
27. Changes in tumorigenesis- and angiogenesis-related gene transcript abundance profiles in ovarian cancer detected by tailored high density cDNA arrays
28. The comparative pathobiology of atherosclerosis and restenosis
29. Direct actions of angiopoietin-1 on human endothelium: Evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors
30. Heterogeneity of the angiogenic response induced in different normal adult tissues by vascular permeability factor/vascular endothelial growth factor
31. Vascular endothelial growth factors are differentially regulated by steroid hormones and antiestrogens in breast cancer cells
32. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
33. Autoradiographic studies of the smooth muscle cells in human arteries
34. Fracture faces of fenestrations and junctions of endothelial cells in human choroidal vessels
35. Cell type-specific expression of angiopoietin-1 and angiopoietin-2 suggests a role in glioblastoma angiogenesis
36. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
37. Increased vascularization in mice overexpressing angiopoietin-1
38. Enhanced expression of Tie2, its ligand angiopoietin-1, vascular endothelial growth factor, and CD31 in human non-small cell lung carcinomas
39. Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma
40. The relation between cell proliferation and the vascular system in a transplanted mouse mammary tumour
41. Angiopoietin-1 protects the adult vasculature against plasma leakage
42. Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1
43. Tumoral vascularity as a prognostic factor in cancer
44. The angiopoietins, tie2 and vascular endothelial growth factor are differentially expressed in the transformation of normal lung to non-small cell lung carcinomas
45. United Kingdom Co-ordinating Committee on Cancer Research (UK CCCR) guidelines for the welfare of animals in experimental neoplasia
46. In situ expression of angiopoietins in astrocytomas identifies angiopoietin-2 as an early marker of tumor angiogenesis