Suppression of cholesterol 7α-hydroxylase transcription and bile acid synthesis by an α1-antitrypsin peptide via interaction with α1-fetoprotein transcription factor

Journal of Biological Chemistry

Volumn 277, Issue 45, 2002, Pages 42973-42980

  Gerbod Giannone, Marie Christine ^a   Castillo Olivares, Antonio Del ^a   Janciauskiene, Sabina ^b   Gil, Gregorio ^b   Hylemon, Phillip B ^a,b  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CHOLESTEROL; DNA; ENZYMES; GENES; RNA;

TRANSCRIPTION FACTORS;

BIOCHEMISTRY;

ALPHA 1 ANTITRYPSIN; ALPHA FETOPROTEIN; BILE ACID; CHOLESTEROL 7ALPHA MONOOXYGENASE; OXYGENASE; STEROL 12ALPHA HYDROXYLASE; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; CHOLESTEROL; DNA BINDING PROTEIN; HEPATOCYTE NUCLEAR FACTOR 4; HYBRID PROTEIN; LUCIFERASE; MLX PROTEIN, HUMAN; PEPTIDE FRAGMENT; PHOSPHOPROTEIN; SERINE PROTEINASE INHIBITOR; TCFL4 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; BILE ACID SYNTHESIS; CELL STRAIN HEPG2; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIVER CELL CULTURE; MALE; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CHEMISTRY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; KINETICS; LIVER CELL; METABOLISM; MOLECULAR GENETICS; MOUSE; PROMOTER REGION; SPRAGUE DAWLEY RAT;

ANIMALIA;

ALPHA 1-ANTITRYPSIN; AMINO ACID SEQUENCE; ANIMALS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BILE ACIDS AND SALTS; CHOLESTEROL; CHOLESTEROL 7-ALPHA-HYDROXYLASE; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEPATOCYTE NUCLEAR FACTOR 4; HEPATOCYTES; HUMANS; KINETICS; LUCIFERASES; MALE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PHOSPHOPROTEINS; PROMOTER REGIONS (GENETICS); RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT FUSION PROTEINS; SERPINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0037044581     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M205089200     Document Type: Article

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