The crystal structure of eosinophil cationic protein in complex with 2′,5′-ADP at 2.0 Å resolution reveals the details of the ribonucleolytic active site

Biochemistry

Volumn 41, Issue 40, 2002, Pages 12100-12106

  Mohan, C Gopi ^a   Boix, Ester ^a,b   Evans, Hazel R ^a   Nikolovski, Zoran ^b   Nogués, M Victòria ^b   Cuchillo, Claudi M ^b   Acharya, K Ravi ^a  

^a University of Bath   (United Kingdom)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC EFFICIENCY;

BACTERIA; CELLS; CRYSTAL STRUCTURE; DISEASES; HYDROGEN BONDS; RNA; STRUCTURAL ANALYSIS; VIRUSES;

PROTEINS;

ADENOSINE 2',5' DIPHOSPHATE; ADENOSINE DIPHOSPHATE; ARGININE; EOSINOPHIL CATIONIC PROTEIN; NEUROTOXIN; PANCREATIC RIBONUCLEASE; RIBONUCLEASE A; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

ALLERGIC DISEASE; ARTICLE; ASTHMA; BINDING SITE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME SPECIFICITY; ENZYME SUBSTRATE; EOSINOPHIL; EPITHELIUM CELL; EXTRACELLULAR MATRIX; HUMAN; HYDROGEN BOND; INFLAMMATION; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPTICAL RESOLUTION; PHOSPHATE TRANSPORT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEIN SECRETION; PROTEIN STRUCTURE; RNA VIRUS; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

ADENOSINE DIPHOSPHATE; AMINO ACID SEQUENCE; BINDING SITES; BLOOD PROTEINS; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; EOSINOPHIL GRANULE PROTEINS; HYDROGEN BONDING; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; RIBONUCLEASES; SEQUENCE ALIGNMENT;

RNA VIRUSES; VERMES;

EID: 0037044330     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0264521     Document Type: Article

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