Synthesis and antitumor activity of 1,5,6-substituted E-3-(2-chloro-3-indolylmethylene)-1,3-dihydroindol-2-ones

Journal of Medicinal Chemistry

Volumn 45, Issue 12, 2002, Pages 2666-2669

  Andreani, Aldo ^a   Granaiola, Massimiliano ^a   Leoni, Alberto ^a   Locatelli, Alessandra ^a   Morigi, Rita ^a   Rambaldi, Mirella ^a   Garaliene, Vida ^b  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b LITHUANIAN UNIVERSITY OF HEALTH SCIENCES   (Lithuania)

Author keywords

[No Author keywords available]

Indexed keywords

3 (2 CHLORO 3 INDOLYLMETHYLENE) 1,3 DIHYDROINDOL 2 ONE DERIVATIVE; 3 (2 CHLORO 5 METHOXY 6 METHYL 3 INDOLYLMETHYLENE) 1,3 DIHYDROINDOL 2 ONE; ANTINEOPLASTIC AGENT; UNCLASSIFIED DRUG; VINCRISTINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; GROWTH INHIBITION; HUMAN; HUMAN CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; CDC2 PROTEIN KINASE; CELL DIVISION; DRUG SCREENING ASSAYS, ANTITUMOR; GUINEA PIGS; HUMANS; INDOLES; MYOCARDIAL CONTRACTION; PAPILLARY MUSCLES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0037030611     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm011123c     Document Type: Article

References (12)

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2. Potential antitumor agents. 25. Synthesis and cytotoxic activity of 3-(2-chloro-3-indolyl-methylene)1,3-dihydroindol-2-ones
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