Imidazo[2,1-b]thiazolylmethylene- and indolylmethylene-2-indolinones: A new class of cyclin-dependent kinase inhibitors. Design, synthesis, and CDK1/cyclin B inhibition

Anti-Cancer Drug Design

Volumn 15, Issue 6, 2000, Pages 447-452

  Andreani, A ^a   Cavalli, A ^a   Granaiola, M ^a   Leoni, A ^a   Locatelli, A ^a   Morigi, R ^a   Rambaldi, M ^a   Recanatini, M ^a   Garnier, M ^a   Meijer, L ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

CDK1; Cytotoxicity; Imidazothiazoles; Indoles

Indexed keywords

(2 CHLOROINDOLYL)METHYLENE 2 INDOLINONE; CYCLIN B; CYCLIN B INHIBITOR; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 1 INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR; IMIDAZO[2,1 B]THIAZOLYLMETHYLENE 2 INDOLINONE DERIVATIVE; IMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; OXINDOLE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; DRUG DESIGN; DRUG DETERMINATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME INHIBITOR INTERACTION; IMAGE ANALYSIS; INHIBITION KINETICS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING;

BINDING SITES; CDC2 PROTEIN KINASE; CYCLIN B; ENZYME INHIBITORS; INDOLES; MODELS, MOLECULAR;

EID: 0034434429     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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