SCOPUS 정보 검색 플랫폼

Journal of the American Chemical Society

Volumn 124, Issue 9, 2002, Pages 1871-1876

Nonaqueous biocatalytic synthesis of new cytotoxic doxorubicin derivatives: Exploiting unexpected differences in the regioselectivity of salt-activated and solubilized subtilisin

(3) Altreuter, David H a Dordick, Jonathan S b Clark, Douglas S a

a University of California (United States)

b RENSSELAER POLYTECHNIC INSTITUTE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

REGIOSELECTIVITY;

ACYLATION; AEROSOLS; DERIVATIVES; ENZYMES; TOLUENE;

BIOCATALYSTS;

14 (2 THIOPHENE ACETATE)DOXORUBICIN; 14 (BENZYLCARBONATE)DOXORUBICIN; AMINE; BUTYRIC ACID DERIVATIVE; CYTOTOXIC AGENT; DOXORUBICIN DERIVATIVE; HYDROXYL GROUP; POTASSIUM CHLORIDE; PROTEINASE; SODIUM CHLORIDE; TOLUENE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; VINYL BUTYRATE;

ACYLATION; AQUEOUS SOLUTION; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER RESISTANCE; CATALYSIS; CHEMICAL REACTION; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; FREEZE DRYING; HUMAN; HUMAN CELL; IC 50; MUCOR; MUCOR JAVANICUS; MULTIDRUG RESISTANCE; REACTION ANALYSIS; STEREOCHEMISTRY;

ANTIBIOTICS, ANTINEOPLASTIC; BREAST NEOPLASMS; CATALYSIS; DOXORUBICIN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LIPASE; MUCOR; POTASSIUM CHLORIDE; SOLUBILITY; SUBSTRATE SPECIFICITY; SUBTILISIN; TUMOR CELLS, CULTURED;

EID: 0037028984 PISSN: 00027863 EISSN: None Source Type: Journal
DOI: 10.1021/ja015977y Document Type: Article

Times cited : (44)

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