메뉴 건너뛰기




Volumn 49, Issue 7, 1996, Pages 669-675

New betaclamycin and aclarubicin analogs obtained by prolonged microbial conversion with an aclarubicin-negative mutant

Author keywords

[No Author keywords available]

Indexed keywords

ACLARUBICIN; BETACLAMYCIN; DRUG ANALOG; UNCLASSIFIED DRUG;

EID: 0029784910     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.49.669     Document Type: Article
Times cited : (11)

References (15)
  • 1
    • 0019254141 scopus 로고
    • Biosynthesis of anthracycline antibiotics by Streptomyces galilaeus. I. Glycosidation of various anthracyclinone by an aclacinomycin-negative mutant and biosynthesis of aclacinomycins from aklavinone
    • OKI, T.; A. YOSHIMOTO, Y. MATSUZAWA, T. TAKEUCHI & H. UMEZAWA: Biosynthesis of anthracycline antibiotics by Streptomyces galilaeus. I. Glycosidation of various anthracyclinone by an aclacinomycin-negative mutant and biosynthesis of aclacinomycins from aklavinone. J. Antibiotics 33: 1331-1340, 1980
    • (1980) J. Antibiotics , vol.33 , pp. 1331-1340
    • Oki, T.1    Yoshimoto, A.2    Matsuzawa, Y.3    Takeuchi, T.4    Umezawa, H.5
  • 2
    • 0019257655 scopus 로고
    • Biosynthesis anthracycline antibiotics by Streptomyces galilaeus. II. Structure of new anthracycline antibiotics obtained by microbial glycosidation and biological activity
    • MATSUZAWA, Y.; A. YOSHIMOTO, T. OKI, H. NAGANAWA, T. TAKEUCHI & H. UMEZAWA: Biosynthesis anthracycline antibiotics by Streptomyces galilaeus. II. Structure of new anthracycline antibiotics obtained by microbial glycosidation and biological activity. J. Antibiotics 33: 1341-1347, 1980
    • (1980) J. Antibiotics , vol.33 , pp. 1341-1347
    • Matsuzawa, Y.1    Yoshimoto, A.2    Oki, T.3    Naganawa, H.4    Takeuchi, T.5    Umezawa, H.6
  • 5
    • 0026725381 scopus 로고
    • Production of new anthracycline antibiotic betaclamycin B by microbial conversion with a specific aclacinomycin-negative mutant
    • YOSHIMOTO, A.; O. JOHDO, Y. WATANABE, H. NISHIDA, R. OKAMOTO & T. TAKEUCHI: Production of new anthracycline antibiotic betaclamycin B by microbial conversion with a specific aclacinomycin-negative mutant. J. Antibiotics 45: 1005-1007, 1992
    • (1992) J. Antibiotics , vol.45 , pp. 1005-1007
    • Yoshimoto, A.1    Johdo, O.2    Watanabe, Y.3    Nishida, H.4    Okamoto, R.5    Takeuchi, T.6
  • 6
    • 0026563993 scopus 로고
    • Production of new anthracycline antibiotics 1-hydroxyoxaunomycin and 6-deoxyoxaunomycin by limited biosynthetic conversion using a daunorubicin-negative mutant
    • YOSHIMOTO, A.; O. JOHDO, H. TONE, R. OKAMOTO, H. NAGANAWA, T. SAWA & T. TAKEUCHI: Production of new anthracycline antibiotics 1-hydroxyoxaunomycin and 6-deoxyoxaunomycin by limited biosynthetic conversion using a daunorubicin-negative mutant. J. Antibiotics 45: 1609-1617, 1992
    • (1992) J. Antibiotics , vol.45 , pp. 1609-1617
    • Yoshimoto, A.1    Johdo, O.2    Tone, H.3    Okamoto, R.4    Naganawa, H.5    Sawa, T.6    Takeuchi, T.7
  • 7
    • 0027096064 scopus 로고
    • Production of new anthracycline antibiotics by microbial 4-O-methylation using a specific daunorubicin-negative mutant
    • JOHDO, O.; H. TONE, R. OKAMOTO, A. YOSHIMOTO & T. TAKEUCHI: Production of new anthracycline antibiotics by microbial 4-O-methylation using a specific daunorubicin-negative mutant. J. Antibiotics 45: 1837-1847, 1992
    • (1992) J. Antibiotics , vol.45 , pp. 1837-1847
    • Johdo, O.1    Tone, H.2    Okamoto, R.3    Yoshimoto, A.4    Takeuchi, T.5
  • 8
    • 0027265863 scopus 로고
    • Microbial glycosidation of some anthracycline antibiotics by an antibiotic-negative mutant of aclarubicin producer
    • JOHDO, O.; H. TONE, R. OKAMOTO, A. YOSHIMOTO, H. NAGANAWA, T. SAWA & T. TAKEUCHI: Microbial glycosidation of some anthracycline antibiotics by an antibiotic-negative mutant of aclarubicin producer. J. Antibiotics 46: 1219-1231, 1993
    • (1993) J. Antibiotics , vol.46 , pp. 1219-1231
    • Johdo, O.1    Tone, H.2    Okamoto, R.3    Yoshimoto, A.4    Naganawa, H.5    Sawa, T.6    Takeuchi, T.7
  • 10
    • 0018593685 scopus 로고
    • Antitumor agents from the bohemic acid complex. 4. Structures of rudolphomycin, minimycin, collinemycin, and alcindoromycin
    • DOYLE, T. W.; D. E. NETTLETON, R. E. GRULICH, D. M. BALITZ, D. L. JOHNSON & A. L. VULCANO: Antitumor agents from the bohemic acid complex. 4. Structures of rudolphomycin, minimycin, collinemycin, and alcindoromycin. J. Am. Chem. Soc, 101: 7041-7049, 1979
    • (1979) J. Am. Chem. Soc , vol.101 , pp. 7041-7049
    • Doyle, T.W.1    Nettleton, D.E.2    Grulich, R.E.3    Balitz, D.M.4    Johnson, D.L.5    Vulcano, A.L.6
  • 12
    • 0025938023 scopus 로고
    • Anthracycline metabolites from Streptomyces violaceus A262. III. New anthracycline obelmycins produced by a variant strain SE2-2385
    • JOHDO, O.; Y. WATANABE, T. ISHIKURA, A. YOSHIMOTO, H. NAGANAWA, T. SAWA & T. TAKEUCHI: Anthracycline metabolites from Streptomyces violaceus A262. III. New anthracycline obelmycins produced by a variant strain SE2-2385. J. Antibiotics 44: 1130-1140, 1991
    • (1991) J. Antibiotics , vol.44 , pp. 1130-1140
    • Johdo, O.1    Watanabe, Y.2    Ishikura, T.3    Yoshimoto, A.4    Naganawa, H.5    Sawa, T.6    Takeuchi, T.7
  • 13
    • 0019799782 scopus 로고
    • Structure-activity relationships of anthracyclines relative to cytotoxicity and effects on macromolecular synthesis in LI210 leukemia cells
    • MATSUZAWA, Y.; T. OKI, T. TAKEUCHI & H. UMEZAWA: Structure-activity relationships of anthracyclines relative to cytotoxicity and effects on macromolecular synthesis in LI210 leukemia cells. J. Antibiotics 34: 1596-1607, 1981
    • (1981) J. Antibiotics , vol.34 , pp. 1596-1607
    • Matsuzawa, Y.1    Oki, T.2    Takeuchi, T.3    Umezawa, H.4
  • 14
    • 0022459864 scopus 로고
    • Intensely potent anthracycline antibiotic oxaunomycin produced by a blocked mutant of the daunomycin-producing microorganism
    • YOSHIMOTO, A.; S. FUJH, O. JOHDO, K. KUBO, T. ISHIKURA, H. NAGANAWA, T. SAWA, T. TAKEUCHI & H. UMEZAWA: Intensely potent anthracycline antibiotic oxaunomycin produced by a blocked mutant of the daunomycin-producing microorganism. J. Antibiotics 39: 902-909, 1986
    • (1986) J. Antibiotics , vol.39 , pp. 902-909
    • Yoshimoto, A.1    Fujh, S.2    Johdo, O.3    Kubo, K.4    Ishikura, T.5    Naganawa, H.6    Sawa, T.7    Takeuchi, T.8    Umezawa, H.9
  • 15
    • 0019211901 scopus 로고
    • Microbial conversion of ε-pyrromycinone and ε-isorhodomycinone to 1-hydroxy-13-dihydrodaunomycin and N-formyl-13-dihydrodaunomycin and their bioactivities
    • YOSHIMOTO, A.; Y. MATSUZAWA, T. OKI, H. NAGANAWA, T. TAKEUCHI & H. UMEZAWA: Microbial conversion of ε-pyrromycinone and ε-isorhodomycinone to 1-hydroxy-13-dihydrodaunomycin and N-formyl-13-dihydrodaunomycin and their bioactivities. J. Antibiotics 33: 1150-1157, 1980
    • (1980) J. Antibiotics , vol.33 , pp. 1150-1157
    • Yoshimoto, A.1    Matsuzawa, Y.2    Oki, T.3    Naganawa, H.4    Takeuchi, T.5    Umezawa, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.