Three-dimensional simulation of grain mixing in three different rotating drum designs for solid-state fermentation

Biotechnology and Bioengineering

Volumn 79, Issue 3, 2002, Pages 284-294

  Schutyser, M A I ^a,b   Weber, F J ^a,b   Briels, W J ^c   Boom, R M ^b   Rinzema, A ^a,b  

^a TOP INSTITUTE FOOD AND NUTRITION   (Netherlands)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c UNIVERSITY OF TWENTE   (Netherlands)

Author keywords

Baffles; Discrete particle simulations; Mixing; Rotating drum; Solid state fermentation

Indexed keywords

FERMENTATION; HEAT TRANSFER; IMAGE ANALYSIS; MASS TRANSFER; MIXING; ROTATING MACHINERY;

DISCRETE PARTICLE SIMULATIONS; ROTATING DRUMS;

BIOTECHNOLOGY;

ACCURACY; ARTICLE; EQUIPMENT DESIGN; GRAIN; HEAT TRANSFER; IMAGE ANALYSIS; PROCESS DESIGN; ROTATION; SIMULATION; SOLID STATE FERMENTATION; TECHNIQUE; THEORETICAL MODEL; VIDEOTAPE;

AIR MOVEMENTS; BIOREACTORS; BIOTECHNOLOGY; COMPUTER SIMULATION; ENTROPY; EQUIPMENT DESIGN; FERMENTATION; MODELS, THEORETICAL; ROTATION; SENSITIVITY AND SPECIFICITY; TRITICUM;

EID: 0037026233     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10277     Document Type: Article

References (20)

1. Allen MP, Tildesly DJ. 1987. Computer simulation of liquids. Oxford, UK: Oxford University Press.
2. Blumberg W, Schlünder E-U. 1996. Transversale Schüttgutbewegung und konvektiver Stoffübergang in Drehrohren. Teil 1: Ohne Hubschaufeln. Chem Eng Proc 35:395-404.
3. Han B, Kiers JL, Nout RMJ. 1999. Solid-substrate fermentation of soybeans with Rhizopus spp.: Comparison of discontinuous rotation with stationary bed fermentation. J Biosci Bioeng 88:205-209.
4. Hardin MT, Mitchell DA, Howes T. 2000. Approach to designing rotating drum bioreactors for solid-state fermentation on the basis of dimensionless design factors. Biotechnol Bioeng 67:264-282.
5. Hogg R, Cahn DS, Healy TW, Fuerstenau DW. 1966. Diffusional mixing in an ideal system. Chem Eng Sci 21:1025-1038.
6. Hoomans BPB. 2000. Granular dynamics of gas-solid two-phase flows. PhD thesis, University of Twente, Enschede, The Netherlands.
7. Iwai T, Hong C-W, Greil P. 1999. Fast particle pair detection algorithms for particle simulations. Int J Mod Phys 10:823-837.
8. Lacey MC. 1954. Developments in the theory of particle mixing. J Appl Chem 4:257-268.
9. Marsh AJ, Stuart DM, Mitchell DA, Howes T. 2000, Characterizing mixing in a rotating drum bioreactor for solid-state fermentation. Biotechnol Lett 22:473-477.
10. McCarthy JJ, Shinbrot T, Metcalfe G, Wolf DE, Ottino JM. 1996. Mixing of granular materials in slowly rotated containers. AIChE J 42:3351-3363.
11. Metcalfe G, Shinbrot T, McCarthy JJ, Ottino JM. 1995. Avalanche mixing of solids. Nature 374:39-41.
12. Mitchell DA, Krieger N, Stuart DM, Pandey A 2000. New developments in solid-state fermentation. II. Rational approaches to the design, operation and scale-up of bioreactors. Proc Biochem 35:1211-1225.
13. Nagel FJI, Tramper J, Bakker MSN, Rinzema A. 2001. Temperature control in a continuously mixed bioreactor for solid-state fermentation. Biotechnol Bioeng 72:219-230.
14. Pandey A, Soccol CR, Mitchell DA. 2000. New developments in solid state fermentation. I. Bioprocesses and products. Proc Biochem 35:1153-1169.
15. Rao SJ, Bhatia SK, Khakar DV. 1991. Axial transport of granular solids in rotating cylinders. Part 2: Experiments in a non-flow system. Powder Technol 67:153-162.
16. Schäfer J, Dippel S, Wolf DE, 1996. Force schemes in simulations of granular materials. J Phys I 6:5-15.
17. Schutyser MAI, Padding JT, Weber FJ, Briels WJ, Rinzema A, Boom R. 2001. Discrete particle simulations predicting mixing behavior of solid substrate particles in a rotating drum. Biotechnol Bioeng 75:666-675.
18. Vu-Quoc L, Zhang X, Walton OR. 2000. A 3-D discrete element method for dry granular flows of ellipsoidal particles. Comput Meth Appl Mech Eng 187:483-528.
19. Weber FJ, Tramper J, Rinzema A. 1999. A simplified material and energy balance approach for process development and scale-up of Coniothyrium minitans conidia production by solid-state cultivation in a packed-bed reactor. Biotechnol Bioeng 65:447-458.
20. Wightman C, Muzzio FJ. 1998. Mixing of granular material in a drum mixer undergoing rotational and rocking motions I. Uniform particles. Powder Technol 98:113-124.