Biological monitoring of exposure to mixtures

Toxicology Letters

Volumn 134, Issue 1-3, 2002, Pages 9-16

  Viau, Claude ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

1 Hydroxypyrene; Biological monitoring; Mixtures; PAH1; PBPK modelling; Toxicokinetic interaction

Indexed keywords

1 HYDROXYPYRENE; BIOLOGICAL MARKER; CARCINOGEN; ENZYME; INDUSTRIAL CHEMICAL; POLYCYCLIC AROMATIC HYDROCARBON; TOLUENE; XYLENE;

AIRBORNE PARTICLE; BIOLOGICAL MONITORING; BIOTRANSFORMATION; BLOOD LEVEL; CALCULATION; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; CORRELATION ANALYSIS; ENVIRONMENTAL EXPOSURE; HUMAN; NONHUMAN; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HEALTH; OXIDATION; PRIORITY JOURNAL; TOXICOKINETICS; WORKPLACE;

ANIMALS; BIOLOGICAL MARKERS; DRUG COMBINATIONS; DRUG INTERACTIONS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; HUMANS; MODELS, BIOLOGICAL; POLYCYCLIC HYDROCARBONS, AROMATIC; PYRENES; XENOBIOTICS;

BOVINE LEUKEMIA VIRUS;

EID: 0037025537     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(02)00158-3     Document Type: Conference Paper

References (27)

1. Urinary 1-hydroxypyrene as a biomarker of exposure to polycyclic aromatic hydrocarbons: Biological monitoring strategies and methodology for determining biological exposure indices for various work environments
2. Urinary excretion kinetics of 1-hydroxypyrene following intravenous administration of binary and ternary mixtures of polycyclic aromatic hydrocarbons in the rat
3. Evaluation of exposure to polycyclic aromatic hydrocarbons in a coke production and a graphite electrode manufacturing plant: Assessment of urinary excretion of 1-hydroxypyrene as a biological indicator of exposure
4. Toxicological evaluation and risk assessment of chemical mixtures
5. A modeling approach to account for toxicokinetic interactions in the calculation of biological hazard index for chemical mixtures
6. Validation of a physiological modeling framework for simulating the toxicokinetics of chemicals in mixtures
7. Experimental designs and risk assessment in combination toxicology-Panel discussion
8. Exposure to complex mixtures: Implications for biological monitoring
9. In vivo suppression of benzene and styrene oxidation by co-administered toluene in rats and effects of phenobarbital
10. Biological monitoring of workers exposed to ethylbenzene and co-exposed to xylene
11. 1-Hydroxypyrene in human urine after exposure to coal tar and a coal tar derived product
12. 1-Hydroxypyrene in urine as a biological indicator of exposure to polycyclic aromatic hydrocarbons in several work environments
13. Ambient and biological monitoring of cokeoven workers: Determinants of the internal dose of polycyclic aromatic hydrocarbons
14. Exposure to PAH compounds among cokery workers in the oil shale industry
15. Occupational PAH exposure: Urinary 1-hydroxypyrene levels of coke oven workers, aluminum smelter pot-room workers, road pavers, and occupationally non-exposed persons in Sweden
16. Toxicokinetics of organic solvents: A review of modifying factors
17. The relationship between polycyclic aromatic hydrocarbons in air and in urine of workers in a Soderberg potroom
18. Biological monitoring VII: Occupational exposures to mixtures of industrial chemicals
19. The importance of measured end-points in demonstrating the occurrence of interactions: A case study with methylchloroform and *m-xylene
20. Effect of simultaneous exposure to toluene and xylene on their respective biological exposure indices in humans
21. Assessment of occupational health risk from multiple exposure: Review of industrial solvent interaction and implication for biological monitoring of exposure
22. Physiologically-based pharmacokinetic modeling of a mixture of toluene and xylene in humans
23. Physiologically based pharmacokinetic modeling of a ternary mixture of alkyl benzenes in rats and humans
24. The marker concept: 1-pyrenol as a biomarker for occupational exposure to polycyclic aromatic hydrocarbons containing pyrene
25. Patterns of 1-hydroxypyrene excretion in volunteers exposed to pyrene by the dermal route
26. Definitions of monitoring activities and their relevance for the practice of occupational health