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Volumn 12, Issue 21, 2002, Pages 3111-3115
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Indoline and piperazine containing derivatives as a novel class of mixed D2/D4 receptor antagonists. Part 2: Asymmetric synthesis and biological evaluation
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Author keywords
[No Author keywords available]
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Indexed keywords
(4 CHLOROBENZYL)PIPERAZINE;
2 [4 (4 CHLOROBENZYL)PIPERAZIN 1 YL] 1 (2 METHY 2,3 DIHYDROINDOL 1 YL)ETHANONE;
2 [4 (4 METHYLBENZYL)PIPERAZIN 1 YL] 1 (2 METHY 2,3 DIHYDROINDOL 1 YL)ETHANONE;
ACETONITRILE;
CLOZAPINE;
DICHLOROMETHANE;
DOPAMINE 2 RECEPTOR;
DOPAMINE 4 RECEPTOR;
DOPAMINE RECEPTOR BLOCKING AGENT;
EMONAPRIDE;
ESTER DERIVATIVE;
HALOPERIDOL;
INDOLINE 2 CARBOXYLIC ACID METHYL ESTER;
KETONE DERIVATIVE;
PIPERAZINE DERIVATIVE;
POTASSIUM CARBONATE;
QUINPIROLE;
TRIFLUOROACETIC ACID;
UNCLASSIFIED DRUG;
ANIMAL EXPERIMENT;
ARTICLE;
BEHAVIORAL SCIENCE;
BINDING AFFINITY;
CATALEPSY;
CONTROLLED STUDY;
DRUG EFFICACY;
DRUG HALF LIFE;
DRUG SCREENING;
DRUG SYNTHESIS;
MALE;
NONHUMAN;
PSYCHOSIS;
RAT;
RAT STRAIN;
RECEPTOR AFFINITY;
AMPHETAMINE;
ANIMALS;
ANTIPSYCHOTIC AGENTS;
BINDING, COMPETITIVE;
CATALEPSY;
CENTRAL NERVOUS SYSTEM STIMULANTS;
CLOZAPINE;
DOPAMINE ANTAGONISTS;
DRUG EVALUATION, PRECLINICAL;
DYSKINESIA, DRUG-INDUCED;
HALF-LIFE;
HALOPERIDOL;
HUMANS;
INDICATORS AND REAGENTS;
INDOLES;
MOTOR ACTIVITY;
PIPERAZINES;
RATS;
RATS, SPRAGUE-DAWLEY;
RECEPTORS, DOPAMINE D2;
RECEPTORS, DOPAMINE D4;
RECOMBINANT PROTEINS;
STEREOISOMERISM;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 0037020743
PISSN: 0960894X
EISSN: None
Source Type: Journal
DOI: 10.1016/S0960-894X(02)00656-X Document Type: Article |
Times cited : (58)
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References (12)
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