Catalytic mechanism of matrix metalloproteinases: Two-layered ONIOM study

Inorganic Chemistry

Volumn 41, Issue 22, 2002, Pages 5659-5666

  Pelmenschikov, Vladimir ^a   Siegbahn, Per E M ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONYL DERIVATIVE; CHELATING AGENT; DIPHENYLPIPERIDINE SULFONAMIDE INHIBITOR; ENZYME INHIBITOR; HYDROGEN; LIGAND; MATRIX METALLOPROTEINASE; METAL; NITROGEN; OXYGEN DERIVATIVE; POLYPEPTIDE; PROTEINASE; PROTON; STROMELYSIN; SULFONAMIDE; UNCLASSIFIED DRUG; WATER; ZINC;

ARTICLE; BINDING SITE; BIOLOGY; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; COMPLEX FORMATION; ENERGY; ENZYME DEGRADATION; ENZYME MECHANISM; EXTRACELLULAR MATRIX; HUMAN; HYDROGEN BOND; HYDROLYSIS; INTERMETHOD COMPARISON; MACROMOLECULE; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FAMILY; RIGIDITY; X RAY ANALYSIS; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CATALYSIS; CHELATING AGENTS; COMPUTATIONAL BIOLOGY; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HUMANS; HYDROGEN BONDING; MATRIX METALLOPROTEINASE 3; MODELS, MOLECULAR; PROTEIN CONFORMATION; WATER; ZINC;

EID: 0037020639     PISSN: 00201669     EISSN: None     Source Type: Journal    
DOI: 10.1021/ic0255656     Document Type: Article

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