Critical role of glutamic acid 202 in the enzymatic activity of stromelysin-1 (MMP-3)

European Journal of Biochemistry

Volumn 268, Issue 3, 2001, Pages 826-831

  Arza, Begoña ^a,b   De Maeyer, Marc ^c   Félez, Jordi ^b   Collen, Désiré ^a,c   Roger Lijnen, H ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b HOSPITAL DURAN I REYNALS   (Spain)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

Matrix metalloproteinases; Site specific mutagenesis; Stromelysin 1

Indexed keywords

4 AMINOPHENYLMERCURIC ACETATE; GLUTAMIC ACID 202; GLUTAMIC ACID DERIVATIVE; PLASMIN; PLASMINOGEN; PROUROKINASE; STROMELYSIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME PURIFICATION; ESCHERICHIA COLI; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ALANINE; ASPARTIC ACID; BINDING SITES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; ESCHERICHIA COLI; GLUTAMIC ACID; HUMANS; HYDROLYSIS; KINETICS; LYSINE; MATRIX METALLOPROTEINASE 3; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHENYLMERCURIC ACETATE; PLASMIN; PLASMINOGEN; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ANALYSIS, DNA; TIME FACTORS; URINARY PLASMINOGEN ACTIVATOR; ZINC;

EID: 0034818299     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2001.01943.x     Document Type: Article

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