Halothane attenuates the cerebroprotective action of several Na+ and Ca2+ channel blockers via reversal of their ion channel blockade

European Journal of Pharmacology

Volumn 452, Issue 2, 2002, Pages 175-181

  Oka, Michiko ^a   Itoh, Yoshinori ^b   Fujita, Takuya ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Ca2+ channel blocker; Cerebral cortex; Halothane; Hypoxia; Na+ channel blocker; Nitric oxide (NO) synthesis

Indexed keywords

ANESTHETIC AGENT; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CINCHOCAINE; CYCLIC AMP; HALOTHANE; ION CHANNEL; LIDOCAINE; NITRIC OXIDE; OMEGA CONOTOXIN; POTASSIUM CHLORIDE; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; TETRODOTOXIN; VERAPAMIL; VERATRIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN PROTECTION; BRAIN SLICE; CONTROLLED STUDY; DRUG EFFECT; HYPOXIC CELL; MALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CALCIUM CHANNEL BLOCKERS; CELL HYPOXIA; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; GLUCOSE; HALOTHANE; MALE; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNEL BLOCKERS;

EID: 0037020451     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)02298-7     Document Type: Article

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