Halothane and isoflurane preferentially depress a slowly inactivating component of Ca2+ channel current in guinea-pig myocytes

Journal of Physiology

Volumn 494, Issue 1, 1996, Pages 91-103

  Pancrazio, Joseph J ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANESTHETIC AGENT; BARIUM ION; CALCIUM CHANNEL; CALCIUM ION; HALOTHANE; ISOFLURANE;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CHANNEL GATING; COMPUTER SIMULATION; CONTROLLED STUDY; DRUG MECHANISM; GAS CHROMATOGRAPHY; GUINEA PIG; MUSCLE CELL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL;

EID: 0030004319     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.1996.sp021478     Document Type: Article

References (40)

1. 2+ channels in guinea pig heart cells. Journal of Physiology 456, 247-265.
2. 2+ is buffered. Circulation Research 68, 897-902.
3. BAUM, V. C., WETZEL, G. T. & KLITZNER, T. S. (1994). Effects of halothane and ketamine on activation and inactivation of myocardial calcium current. Journal of Cardiovascular Pharmacology 23, 799-805.
4. BOSNJAK, Z. J., SUPAN, F. D. & RUSCH, N. J. (1991). The effects of halothane, enflurane, and isoflurane on calcium current in isolated canine ventricular cells. Anesthesiology 74, 340-345.
5. COLQUHOUN D. & HAWKES, A. G. (1981). On the stochastic properties of single ion channels. Proceedings of the Royal Society of London B 211, 205-235.
6. COLQUHOUN D. & HAWKES, A. G. (1983). The principles of the stochastic interpretation of ion channel mechanisms. In Single Channel Recording, ed. SAKMANN B. & NEHER, E., pp. 135-175, Plenum Press, New York.
7. 2+ release channel of cardiac sarcoplasmic reticulum by volatile anesthetics. Anesthesiology 81, 459-469.
8. DRENGER, B., QUIGG, M. & BLANCK, T. J. J. (1991). Volatile anesthetics depress calcium channel blocker binding to bovine cardiac sarcolemma. Anesthesiology 74, 155-165.
9. ESKINDER, H., RUSCH, N. J., SUPAN, F. D., KAMPINE, J. P. & BOSNJAK, Z. J. (1991). The effects of volatile anesthetics on L-type and T-type calcium channel currents in canine purkinje cells. Anesthesiology 74, 919-926.
10. FIRESTONE, L. L., MILLER, J. C. & MILLER, K. W. (1986). Tables of physical and pharmacological properties of anesthetics. In Molecular and Cellular Mechanisms of Anesthetics, ed. ROTH, S. H. & MILLER, K. W., pp. 455-470. Plenum Press, New York.
11. HAMILL, O. P., MARTY, A., NEHER, E., SAKMANN, B. & SIGWORTH, F. J. (1981). Improved patch-clamp techniques for high-resolution current recordings from cells and cell-free membrane patches. Pflügers Archiv 391, 85-100.
12. 2+ currents in single bullfrog atrial myocytes. Anesthesiology 84, 377-383.
13. 2+ channels. Neuron 12, 1301-1318.
14. KASS, R. S. & SANGUINETTI, M. C. (1984). Calcium channel inactivation in the calf cardiac Purkinje fiber: evidence for voltage-and calcium-mediated mechanisms. Journal of General Physiology 84, 705-726.
15. LEE, K. S., MARBAN, E. & TSIEN, R. W. (1985). Inactivation of calcium channels in mammalian heart cells: joint dependence on membrane potential and intracellular calcium. Journal of Physiology 364, 395-411.
16. LYNCH, C. III (1986). Differential depression of myocardial contractility by halothane and isoflurane in vitro. Anesthesiology 64, 620-631.
17. LYNCH, C. III (1990). Differential depression of myocardial contractility by volatile anesthetics in vitro: comparison with uncouplers of excitation-contraction coupling. Journal of Cardiovascular Pharmacology 15, 655-665.
18. LYNCH, C. III & FRAZER, M. J. (1989). Depressant effects of the volatile anesthetics upon rat and amphibian ventricular myocardium: insights into anesthetic mechanisms of action. Anesthesiology 70, 511-522.
19. LYNCH, C. III, VOGEL, S. & SPERELAKIS, N. (1981). Halothane depression of myocardial slow action potentials. Anesthesiology 55, 360-368.
20. 2+ uptake and Ca-ATPase activity of cardiac sarcoplasmic reticulum. In Anesthesia and Cardiovascular Disease - Advances in Pharmacology 31, ed. BOSNJAK, Z. J. & KAMPINE, J. P., pp. 145-165. Academic Press, San Diego.
21. + channel in guinea pig ventricular myocytes. Journal of Membrane Biology 122, 33-42.
22. 1C) expressed in Xenopus oocytes. Biophysical Journal 66, 1895-1903.
23. NIGGLI, E., MAURER, R. P. & WEINGART, R. (1989). Effects of general anesthetics on current flow across membranes in guinea pig myocytes. American Journal of Physiology 256, C273-281.
24. PANCRAZIO, J. J. (1993). PCS: An IBM-compatible microcomputer program for the analysis and display of voltage-clamp data. Computer Methods and Programs in Biomedicine 40, 175-180.
25. PANCRAZIO, J. J. (1995). Ion channel events simulated with the program SIMSTATE. Computer Methods and Programs in Biomedicine 46, 165-174.
26. PANCRAZIO, J. J., JOHNSON, P. A. & LYNCH, C. III (1994). A major role for calcium-dependent potassium current in action potential repolarization in adrenal chromaffin cells. Brain Research 668, 246-251.
27. PANCRAZIO, J. J. & LYNCH, C. III (1993). Alteration of myocardial calcium current kinetics by halothane. Anesthesiology 75, A618.
28. 2+ overload. Cardiovascular Research 28, 505-514.
29. QIN, Z., SZABO, G. & CAFISO, D. S. (1995). Anesthetics reduce the magnitude of the membrane dipole potential: measurements in lipid vesicles using voltage-sensitive spin probes. Biochemistry 34, 5536-5543.
30. RICHARD, S., CHARNET, P. & NERBONNE, J. M. (1993). Interconversion between distinct gating pathways of the high threshold calcium channel in rat ventricular myocytes. Journal of Physiology 462, 197-228.
31. 2+ channel gating differentially modulated by physiological stimuli. American Journal of Physiology 258, H1872-1881.
32. STEVENS, W. C., CROMWELL, T. H., HALSEY, M. J., EGER, E. I., SHAKESPEARE, T. F. & BALMAN, S. H. (1971). Cardiovascular effects of a new inhalational anesthetic, forane, in human volunteers at a constant arterial carbon dioxide tension. Anesthesiology 35, 8-16.
33. TAKAHASHI, H., PUTTICK, R. M. & TERRAR, D. A. (1994). The effects of propofol and enflurane on single calcium channel currents of guinea-pig isolated ventricular myocytes. British Journal of Pharmacology 111, 1147-1153.
34. TERRAR, D. A. & VICTORY, J. G. G. (1988a). Effects of halothane on membrane currents associated with contraction in single myocytes isolated from guinea-pig ventricle. British Journal of Pharmacology 94, 500-508.
35. TERRAR, D. A. & VICTORY, J. G. G. (1988b). Isoflurane depresses membrane currents associated with contraction in myocytes isolated from guinea pig ventricle. Anesthesiology 69, 742-749.
36. WHEELER, D. M., RICE, R. T., HANSFORD, R. G. & LAKATTA, E. G. (1988). The effect of halothane on the free calcium concentration of isolated rat heart cells. Anesthesiology 69, 578-583.
37. 2+ channel current and accelerates current decay in guinea pig portal vein smooth muscle cells. Journal of Pharmacology and Experimental Therapeutics 271, 1159-1166.
38. 2+ mobilization in single rat ventricular myocytes. Anesthesiology 75, 1075-1086.
39. YUAN, W. L. & BERS, D. M. (1994). Ca-dependent facilitation of cardiac Ca current is due to Ca-calmodulin-dependent protein-kinase. American Journal of Physiology 267, H982-993.
40. ZONG, S., ZHOU, J. & TANABE, T. (1994). Molecular determinants of calcium-dependent inactivation in cardiac L-type calcium channels. Biochemical Biophysical Research Communications 201, 1117-1123.