Central nervous system sodium channels are significantly suppressed at clinical concentrations of volatile anesthetics

Anesthesiology

Volumn 84, Issue 5, 1996, Pages 1223-1233

  Rehberg, Benno ^a   Xiao, Yong Hong ^a   Duch, Daniel S ^b  

^a Department of Anesthesiology ^*  (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Anesthetic mechanisms: anesthetic protein interaction; Anesthetics, volatile: desflurane; diethylether; enflurane; halothane; isoflurane; sevoflurane; Brain, central nervous system: sodium channel inactivation, sodium channels; Measurement techniques: patch clamp

Indexed keywords

DESFLURANE; ENFLURANE; ETHER; HALOTHANE; INHALATION ANESTHETIC AGENT; ISOFLURANE; SEVOFLURANE; SODIUM CHANNEL;

ANIMAL CELL; ARTICLE; CELL MEMBRANE POTENTIAL; CENTRAL NERVOUS SYSTEM; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; HYPERPOLARIZATION; INHALATION ANESTHESIA; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; SODIUM CURRENT;

ANESTHETICS, INHALATION; ANIMALS; BRAIN; CHO CELLS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; RATS; SODIUM CHANNELS;

EID: 0029991260     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199605000-00025     Document Type: Article

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