Inhibition of methylcholanthrene-induced carcinogenesis by an interferon γ receptor-dependent foreign body reaction

Journal of Experimental Medicine

Volumn 195, Issue 11, 2002, Pages 1479-1490

  Qin, Zhihai ^a   Kim, Hye Jung ^b   Hemme, Jens ^a,b   Blankenstein, Thomas ^a,b  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Encapsulation; Immune surveillance; Inflammation; Tissue damage; Tissue repair

Indexed keywords

3 METHYLCHOLANTHRENE; GAMMA INTERFERON RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; DNA DAMAGE; ENCAPSULATION; FLOW CYTOMETRY; FOREIGN BODY REACTION; IMMUNOSURVEILLANCE; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; TISSUE INJURY; TISSUE REPAIR;

AGE FACTORS; ANIMALS; BONE MARROW TRANSPLANTATION; CARCINOGENS; CHIMERA; DIFFUSION; DNA DAMAGE; FIBROSARCOMA; FLOW CYTOMETRY; FOREIGN-BODY REACTION; GENE DELETION; INTERFERON TYPE II; METHYLCHOLANTHRENE; MICE; RECEPTORS, INTERFERON; TIME FACTORS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0037013967     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20011887     Document Type: Article

References (65)

1. Chapter 9: Epidemiology of cancer
2. Multistage carcinogenesis in mouse skin
3. Frequent p53 mutations in chemically induced murine fibrosarcoma
4. Analysis of the c-myc, K-ras and p53 genes in methylcholanthrene-induced mouse sarcomas
5. Of mice and men: A critical reappraisal of the two-stage theory of carcinogenesis
6. Fibrogenic cytokines: The role of immune mediators in the development of scar tissue
7. Wound repair: An overview
8. Inflammation and cancer
9. Beobachtungen an experimentellem tumorwachstum
10. The experimental disclosure of latent neoplastic changes in tarred skin
11. Conditional neoplasms and subthreshold neoplastic states: A study of the tar tumors of rabbits
12. The effect of aging and interval between primary and secondary treatment in two-stage carcinogenesis on mouse skin
13. Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis
14. MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis
15. Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy
16. Suppression of intestinal polyposis in Apc δ716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)
17. Immunity and neoplasia in Mollusks
18. Innate immunity of insects
19. Biological mediators of insect immunity
20. Alloimmune memory is absent in Hymeniacidon sinapium, a marine sponge
21. Tissue reaction to foreign materials
22. Asbestos-related cancer and the amphibole hypothesis. The first documentation of the association
23. Cellular responses to interferon-γ
24. Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation
25. Interleukin 3-dependent and -independent mast cells stimulated with IgE and antigen express multiple cytokines
26. Reciprocal regulation of polarized cytokine production by effector B and T cells
27. Tumor rejection by disturbing tumor stroma cell interactions
28. Disturbed MHC regulation in the IFN-γ knockout mouse. Evidence for three states of MHC expression with distinct roles for IFN-γ
29. Immune response in mice that lack the interferon-γ receptor
30. + T cell-mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFN-γ receptor expression by nonhematopoietic cells
31. Interferon-γ elicits arteriosclerosis in the absence of leukocytes
32. Genetic background alters the spectrum of tumors that develop in p53-deficient mice
33. Mechanisms of rejection induced by tumor cell-targeted gene transfer of interleukin 2, interleukin 4, interleukin 7, tumor necrosis factor, or interferon γ
34. Tumor growth inhibition mediated by lymphotoxin: Evidence of B lymphocyte involvement in the antitumor response
35. Tumor suppression after tumor cell-targeted tumor necrosis factor α gene transfer
36. Enhanced growth of primary tumors in cancer-prone mice after immunization against the mutant region of an inherited oncoprotein
37. Regulation of type VI collagen synthesis in transformed mesenchymal cells
38. Down-regulation of collagen XII in transformed mesenchymal cells
39. Preparation and stability of ampouled polycyclic aromatic hydrocarbon solutions
40. Polycyclic aromatic hydrocarbons in human bronchial carcinoma
41. Lung retention and metabolic fate of inhaled benzo(a)pyrene associated with diesel exhaust particles
42. Polycyclic aromatic hydrocarbons retained in rat lung exposed to diesel engine exhaust
43. Determination of polycyclic aromatic hydrocarbons in the lung
44. Average daily respiratory intake of polycyclic aromatic hydrocarbons in ambient air determined by capillary gas chromatography
45. Tumor-promoting phorbol esters cause a stable reduction of dermal collagen in mouse skin
46. Periphere lungenkrebse auf dem boden pleuranaher narben
47. Die narbenkrebse der lungen
48. Scar cancers of the lung: Origin and significance
49. Smoking cessation and mortality trends among 118,000 Californians, 1960-1997
50. Interferon-γ-receptor deficiency in an infant with fatal bacille Calmette-Guerin infection
51. A mutation in the interferon-γ-receptor gene and susceptibility to mycobacterial infection
52. Immunity to intracellular bacteria
53. The concept of immunological surveillance
54. Immune surveillance against virus-induced tumors and nonrejectability of spontaneous tumors: Contrasting consequences of host versus tumor evolution
55. Tumor Immunology
56. Chemical carcinogenesis in nude mice: Comparison between nude mice from homozygous matings and heterozygous matings and effect of age and carcinogen dose
57. MCA sarcomas induced in scid mice are more immunogenic than MCA sarcomas induced in congenic, immunocompetent mice
58. Surveillance, latency and the two levels of MCA-induced tumor immunogenicity
59. Metabolic, molecular genetic and toxicological aspects of the acetylation polymorphism in inbred mice
60. Decreased tumor surveillance in perforin-deficient mice
61. Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice
62. Differential tumor surveillance by natural killer (NK) and NKT cells
63. IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity
64. Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development