Age differences in phosphodiesterase type-IV and its functional response to dopamine D1 receptor modulation in the living brain: A PET study in conscious monkeys

Synapse

Volumn 44, Issue 3, 2002, Pages 139-145

  Harada, Norihiro ^a   Nishiyama, Shingo ^a   Ohba, Hiroyuki ^a   Sato, Kengo ^a   Kakiuchi, Takeharu ^a   Tsukada, Hideo ^a,b  

^a Central Research Laboratory   (Japan)

^b HAMAMATSU PHOTONICS K K   (Japan)

Author keywords

11C rolipram; 11C SCH23390; Dopamine D1 receptor; Monkey brain; Phosphodiesterase type IV; Positron emission tomography

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; CYCLIC AMP; DOPAMINE 1 RECEPTOR; DOPAMINE 1 RECEPTOR BLOCKING AGENT; PHOSPHODIESTERASE IV; ROLIPRAM;

ADOLESCENT; AGED; AGING; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DOSE RESPONSE; FRONTAL CORTEX; MALE; MONKEY; NEUROMODULATION; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RECEPTOR BINDING;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; AGING; ANIMALS; BRAIN; CARBON RADIOISOTOPES; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; MACACA MULATTA; MALE; RECEPTORS, DOPAMINE D1; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0037013703     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/syn.10067     Document Type: Article

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