Stress signals activate natural killer cells

Journal of Experimental Medicine

Volumn 196, Issue 11, 2002, Pages 1399-1402

  Long, Eric O ^a   Rajagopalan, Sumati ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD94 ANTIGEN; CELL RECEPTOR; CYTOKINE; HEAT SHOCK PROTEIN; HLA B ANTIGEN; HLA C ANTIGEN; HLA E ANTIGEN; INTERFERON; LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE; POLYSACCHARIDE; RECEPTOR PROTEIN;

ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; BINDING AFFINITY; CELL ACTIVATION; CELL ACTIVITY; CELL FUNCTION; CELL INTERACTION; CPG ISLAND; HEMATOPOIETIC CELL; HYPOTHESIS; IMMUNOSURVEILLANCE; INFECTION; INFLAMMATION; LIGAND BINDING; LYSIS; MICROORGANISM; MOLECULAR RECOGNITION; NATURAL KILLER CELL; NOTE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SECRETION; SIGNAL TRANSDUCTION; STRESS; TARGET CELL;

ANTIGENS, CD; ANTIGENS, CD94; CHAPERONIN 60; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; KILLER CELLS, NATURAL; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; PROTEIN SORTING SIGNALS; RECEPTORS, IMMUNOLOGIC;

EID: 0037011123     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021747     Document Type: Note

References (29)

1. Bauer, S., V. Groh, J. Wu, A. Steinle, J.H. Phillips, L.L. Lanier, and T. Spies. 1999. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science. 285:727-729.
2. Cosman, D., J. Müllberg, C.L. Sutherland, W. Chin, R. Armitage, W. Fanslow, M. Kubin, and N.J. Chalupny. 2001. ULBPs, novel MHC class I-related molecules bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. Immunity. 14:123-133.
3. Diefenbach, A., E.R. Jensen, A.M. Jamieson, and D.H. Raulet. 2001. Rael and H60 ligands of the NKG2D receptor stimulate tumour immunity. Nature. 413:165-171.
4. Cerwenka, A., J.L. Baron, and L.L. Lanier. 2001. Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo. Proc. Natl. Acad. Sci. USA. 98: 11521-11526.
5. Michaëlsson, J., C. Teixeira de Matos, A. Achour, L.L. Lanier, K. Kärre, and K. Söderström. 2002. HLA-E-mediated presentation of an hsp60 signal peptide prevents natural killer (NK) cell inhibitory receptor engagement: A novel mechanism for NK cell detection of stressed cells. J. Exp. Med. 196:1403-1414.
6. Kärre, K., H.G. Ljunggren, G. Piontek, and R. Kiessling. 1986. Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy. Nature. 319: 675-678.
7. Long, E.O., and S. Rajagopalan. 2000. HLA class I recognition by killer cell Ig-like receptors. Semin. Immunol. 12:101-108.
8. Raulet, D.H., R.E. Vance, and C.W. McMahon. 2001. Regulation of the natural killer cell receptor repertoire. Annu. Rev. Immunol. 19:291-330.
9. Valiante, N.M., M. Uhrberg, H.G. Shilling, K. Lienert- Weidenbach, K.L. Arnett, A. D'Andrea, J.H. Phillips, L.L. Lanier, and P. Parham. 1997. Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors. Immunity. 7:739-751.
10. Moretta, A., C. Bottino, M. Vitale, D. Pende, C. Cantoni, M.C. Mingari, R. Biassoni, and L. Moretta. 2001. Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu. Rev. Immunol. 19:197-223.
11. Cerwenka, A., and L.L. Lanier. 2001. Natural killer cells, viruses, and cancer. Nat. Rev. Immunol. 1:41-49.
12. Groh, V., R. Rhinehart, J. Randolph-Habecker, M.S. Topp, S.R. Riddell, and T. Spies. 2001. Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells. Nat. Immunol. 2:255-260.
13. Das, H., V. Groh, C. Kuijl, M. Sugita, C.T. Morita, T. Spies, and J.F. Bukowski. 2001. MICA engagement by human Vgamma2Vdelta2 T cells enhances their antigen-dependent effector function. Immunity. 15:83-93.
14. Tieng, V., C. Le Bouguénec, L. Du Merle, P. Bertheau, P. Desreumaux, A. Janin, D. Charron, and A. Toubert. 2002. Binding of Escherichia coli adhesin AfaE to CD55 triggers cell-surface expression of the MHC class I-related molecule MICA. Proc. Natl. Acad. Sci. USA. 99:2977-2982.
15. Jamieson, A.M., A. Diefenbach, C.W. McMahon, N. Xiong, J.R. Carlyle, and D.H. Raulet. 2002. The role of the NKG2D immunoreceptor in immune cell activation and natural killing. Immunity. 17:19-29.
16. O'Callaghan, C.A., J. Tormo, B.E. Willcox, V.M. Braud, B.K. Jakobsen, D.I. Stuart, A.J. McMichael, J.I. Bell, and E.Y. Jones. 1998. Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E. Mol. Cell. 1:531-541.
17. Brooks, A.G., F. Borrego, P.E. Posch, A. Patamawenu, C.J. Scorzelli, M. Ulbrecht, E.H. Weiss, and J.E. Coligan. 1999. Specific recognition of HLA-E, but not classical, HLA class I molecules by soluble CD94/NKG2A and NK cells. J. Immunol. 162:305-313.
18. Valés-Gómez, M., H.T. Reyburn, R.A. Erskine, M. López-Botet, and J.L. Strominger. 1999. Kinetics and peptide dependency of the binding of the inhibitory NK receptor CD94/NKG2-A and the activating receptor CD94/NKG2-C to HLA-E. EMBO J. 18:4250-4260.
19. b peptide binding specificity and the capacity of CD94/NKG2A to discriminate between Qa-1-peptide complexes. J. Exp. Med. 192:613-623.
20. Tomasec, P., V.M. Braud, C. Rickards, M.B. Powell, B.P. McSharry, S. Gadola, V. Cerundolo, L.K. Borysiewicz, A.J. McMichael, and G.W.G. Wilkinson. 2000. Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40. Science. 287:1031-1033.
21. Llano, M., N. Lee, F. Navarro, P. García, J.P. Albar, D.E. Geraghty, and M. López-Botet. 1998. HLA-E-bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors: Preferential response to an HLA-G-derived nonAm. Eur. J. Immunol. 28:2854-2863.
22. Romagnani, C., G. Pietra, M. Falco, E. Millo, P. Mazzarino, R. Biassoni, A. Moretta, L. Moretta, and M.C. Mingari. 2002. Identification of HLA-E-specific alloreactive T lymphocytes: A cell subset that undergoes preferential expansion in mixed lymphocyte culture and displays a broad cytolytic activity against allogeneic cells. Proc. Natl. Acad. Sci. USA. 99: 11328-11333.
23. Malnati, M.S., M. Peruzzi, K.C. Parker, W.E. Biddison, E. Ciccone, A. Moretta, and E.O. Long. 1995. Peptide specificity in the recognition of MHC class I by natural killer cell clones. Science. 267:1016-1018.
24. Rajagopalan, S., and E.O. Long. 1997. The direct binding of a p58 killer cell inhibitory receptor to human histocompatibility leukocyte antigen (HLA)-Cw4 exhibits peptide selectivity. J. Exp. Med. 185:1523-1528.
25. Boyington, J.C., S.A. Motyka, P. Schuck, A.G. Brooks, and P.D. Sun. 2000. Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand. Nature. 405:537-543.
26. Fan, Q.R., E.O. Long, and D.C. Wiley. 2001. Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex. Nat. Immunol. 2:452-460.
27. Tormo, J., K. Natarajan, D.H. Margulies, and R.A. Mariuzza. 1999. Crystal structure of a lectin-like natural killer cell receptor bound to its MHC class I ligand. Nature. 402:623-631.
28. Matsumoto, N., M. Mitsuki, K. Tajima, W.M. Yokoyama, and K. Yamamoto. 2001. The functional binding site for the C-type lectin-like natural killer cell receptor Ly49A spans three domains of its major histocompatibility complex class I ligand. J. Exp. Med. 193:147-157.
29. Correa, I., and D.H. Raulet. 1995. Binding of diverse peptides to MHC class I molecules inhibits target cell lysis by activated natural killer cells. Immunity. 2:61-71.