A kinetic trap is an intrinsic feature in the folding pathway of single-chain Fv fragments

Biophysical Chemistry

Volumn 96, Issue 2-3, 2002, Pages 273-284

  Hoyer, Wolfgang ^a   Ramm, Kathrin ^a   Plückthun, Andreas ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Domain interface; Kinetic trap; Protein folding; ScFv

Indexed keywords

M PROTEIN; PROLINE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; GUANIDINE; IMMUNOGLOBULIN FRAGMENT; IMMUNOGLOBULIN FV;

ARTICLE; ISOMERISM; KINETICS; MODEL; MUTATION; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN INTERACTION; RIBOSOME; SIGNAL TRANSDUCTION; CHEMISTRY; DRUG EFFECT; GENETICS; HUMAN; ISOLATION AND PURIFICATION; PROTEIN DENATURATION; PROTEIN RENATURATION; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; SPECTROSCOPY;

GUANIDINE; HUMANS; IMMUNOGLOBULIN FRAGMENTS; KINETICS; MUTAGENESIS, SITE-DIRECTED; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN RENATURATION; PROTEIN STRUCTURE, TERTIARY; SPECTRUM ANALYSIS;

EID: 0037007446     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-4622(02)00022-4     Document Type: Article

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