Comparison of the amide proton exchange behavior of the rapidly formed folding intermediate and the native state of an antibody scFv fragment

FEBS Letters

Volumn 407, Issue 1, 1997, Pages 42-46

  Freund, Cristian ^a   Gehrig, Peter ^a   Holak, Tad A ^b   Plückthun, Andreas ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

H d exchange experiment; Mass spectrometry; Nuclear magnetic resonance; scFv fragment

Indexed keywords

AMIDE; ANTIBODY; PROTON;

ARTICLE; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING;

AMIDES; AMINO ACID SEQUENCE; ANTIBODIES; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTONS;

EID: 0031582218     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)00306-2     Document Type: Article

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