Characterization of intrastriatal recombinant adeno-associated virus- mediated gene transfer of human tyrosine hydroxylase and human GTP- cyclohydrolase I in a rat model of Parkinson's disease

Journal of Neuroscience

Volumn 18, Issue 11, 1998, Pages 4271-4284

  Mandel, R J ^a   Rendahl, K G ^a   Spratt, S K ^a   Snyder, R O ^a   Cohen, L K ^a   Leff, S E ^a  

^a CELL GENESYS INC   (United States)

Author keywords

Gene therapy; GTP cyclohydrolase I; L dihydroxyphenylalanine; Parkinson's disease; Recombinant adeno associated virus; Tyrosine hydroxylase

Indexed keywords

DOPAMINE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; TYROSINE 3 MONOOXYGENASE; VIRUS VECTOR;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DOPAMINE BRAIN LEVEL; DOPAMINE RELEASE; GENE EXPRESSION REGULATION; GENE TARGETING; GENE THERAPY; NONHUMAN; NUCLEOTIDE SEQUENCE; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; RETROVIRUS; TRANSGENE; TRANSGENIC ANIMAL;

EID: 0032101756     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-11-04271.1998     Document Type: Article

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