Recruitment of Scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein

Current Biology

Volumn 12, Issue 7, 2002, Pages 531-539

  Mathew, Dennis ^a   Gramates, L Sian ^a   Packard, Mary ^a   Thomas, Ulrich ^b   Bilder, David ^c   Perrimon, Norbert ^c   Gorczyca, Michael ^a   Budnik, Vivian ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b LEIBNIZ INSTITUTE FOR NEUROBIOLOGY   (Germany)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISCS LARGE 1 PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; GUANYLATE KINASE; INSECT PROTEIN; MEMBRANE PROTEIN; NUCLEOSIDE MONOPHOSPHATE KINASE; SCRIBBLE PROTEIN, DROSOPHILA; TUMOR SUPPRESSOR PROTEIN;

ANIMAL; ARTICLE; DROSOPHILA MELANOGASTER; GENETICS; METABOLISM; SYNAPSE;

ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GUANYLATE KINASE; INSECT PROTEINS; MEMBRANE PROTEINS; NUCLEOSIDE-PHOSPHATE KINASE; SYNAPSES; TUMOR SUPPRESSOR PROTEINS;

EID: 0037006796     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)00758-3     Document Type: Article

References (44)

1. Molecular determinants of presynaptic active zones
2. Drosophila larval neuromuscular junction: Molecular components and mechanisms underlying synaptic plasticity
3. SAP90 binds and clusters kainate receptors causing incomplete desensitization
4. Heteromultimerization and NMDA receptor-clustering activity of Chapsyn-110, a member of the PSD-95 family of proteins
5. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95
6. A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II
7. Citron, a Rho-target, interacts with PSD-95/SAP-90 at glutamatergic synapses in the thalamus
8. Binding of neuroligins to PSD-95
9. Synaptic clustering of the cell adhesion molecule fasciclin II by discs-large and its role in the regulation of presynaptic structure
10. Essential role for dlg in synaptic clustering of Shaker K+ channels in vivo
11. GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules
12. SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density
13. Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin
14. Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP/GKAP family
15. Localization of postsynaptic density-93 to dendritic microtubules and interaction with microtubule-associated protein 1A
16. GAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytes
17. Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP
18. Identification of an intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95
19. An intramolecular interaction between Src homology 3 domain and guanylate kinase-like domain required for channel clustering by postsynaptic density-95/SAP90
20. Intramolecular interactions regulate SAP97 binding to GKAP
21. Regulation of synapse structure and function by the Drosophila tumor suppressor gene dlg
22. Synaptic targeting and localization of discs-large is a stepwise process controlled by different domains of the protein
23. Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors
24. Localization of apical epithelial determinants by the basolateral PDZ protein Scribble
25. Using the 2-hybrid system to detect protein-protein interactions
26. The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions
27. Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex
28. N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases
29. Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffold
30. Drosophila kelch is an oligomeric ring canal actin organizer
31. Recognition of unique carboxyl-terminal motifs by distinct PDZ domains
32. The Drosophila tumor suppressor gene, dlg, is involved in structural plasticity at a glutamatergic synapse
33. Insulin-like receptor and insulin-like peptide are localized at neuromuscular junctions in Drosophila
34. Genetic dissection of structural and functional components of synaptic plasticity. I. Fasciclin II controls synaptic stabilization and growth
35. Watching a synapse grow: Noninvasive confocal imaging of synaptic growth in Drosophila
36. Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins
37. Regulation of DLG localization at synapses by CaMKII-dependent phosphorylation
38. Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins
39. Structure of the enabled/VASP homology 1 domain-peptide complex: A key component in the spatial control of actin assembly
40. Synaptic scaffolding proteins in rat brain. Ankyrin repeats of the multidomain Shank protein family interact with the cytoskeletal protein alpha-fodrin
41. Conversion of lacZ enhancer trap lines to GAL4 lines using targeted transposition in Drosophila melanogaster
42. Mutational analysis of Drosophila synaptotagmin demonstrates its essential role in Ca(2+)-activated neurotransmitter release
43. Paralysis and early death in cysteine string protein mutants of Drosophila
44. Invertebrate synapsins: A single gene codes for several isoforms in Drosophila