Unusual genetic architecture of natural variation affecting drug resistance in Drosophila melanogaster

Genetical Research

Volumn 80, Issue 3, 2002, Pages 205-213

  Carrillo, Roland ^a   Gibson, Greg ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; DOPAMINE; NICOTINE; OCTOPAMINE; TYRAMINE;

BACKCROSSING; CONTROLLED STUDY; CORRELATION FUNCTION; CROSSING OVER; DROSOPHILA MELANOGASTER; DRUG EXPOSURE; FEMALE; GENE INTERACTION; GENETIC ANALYSIS; GENETIC EPISTASIS; GENETIC LINE; GENETIC VARIABILITY; GENOTYPE; INGESTION; MALE; MULTIDRUG RESISTANCE; NONHUMAN; QUANTITATIVE GENETICS; REVIEW; SENSITIVITY ANALYSIS; SEX DIFFERENCE; STARVATION; SURVIVAL TIME;

ANALYSIS OF VARIANCE; ANIMALS; CROSSES, GENETIC; DROSOPHILA MELANOGASTER; FEMALE; INSECTICIDE RESISTANCE; MALE; VARIATION (GENETICS);

ARACHNIDA; DROSOPHILA MELANOGASTER; HEXAPODA; MELANOGASTER;

EID: 0037000002     PISSN: 00166723     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0016672302005888     Document Type: Review

References (26)

1. Andretic, R., Chaney, S. & Hirsh, J. (1999). Requirement of circadian genes for cocaine sensitization in Drosophila. Science 285, 1066-1068.
2. Ashton, K., Wagoner, A. P., Carrillo, R. & Gibson, G. (2001). Quantitative trait loci for the monoamine-related traits heart rate and headless behavior in Drosophila melanogaster. Genetics 157, 283-294.
3. Bainton, R. J., Tsai, L., Singh, C., Moore, M., Neckameyer, W. S. & Heberlein, U. (2000). Dopamine modulates acute responses to cocaine, nicotine and ethanol in Drosophila. Current Biology 10, 187-194.
4. Clark, A. M. & Clark, E. G. (1968). The genetic effects of caffeine in Drosophila melanogaster. Mutation Research 6, 227-234.
5. Dubnau, J. & Tully, T. (1998). Gene discovery in Drosophila: new insights for learning and memory. Annual Review of Neuroscience 21, 407-444.
6. Evans, W. E. & Relling, M. V. (1999). Pharmacogenomics: translating functional genomics into rational therapeutics. Science 286, 487-491.
7. Fryxell, K. J. (1995). The evolutionary divergence of neurotransmitter receptors and second-messenger pathways. Journal of Molecular Evolution 4, 85-97.
8. Goodwin, S. F., Del Vecchio, M., Velinzon, K., Hogel, C., Russell, S. R., Tully, T. & Kaiser, K. (1997). Defective learning in mutants of the Drosophila gene for a regulatory subunit of cAMP-dependent protein kinase. Journal of Neuroscience 17, 8817-8827.
9. Harshman, L. G., Moore, K. M., Sty, M. A. & Magwire, M. M. (1999). Stress resistance and longevity in selected lines of Drosophila melanogaster. Neurobiology of Aging 20, 521-529.
10. Heberlein, U. (2000). Genetics of alcohol-induced behaviors in Drosophila. Alcohol Research and Health 24, 185-188.
11. Hen, R. (1993). Structural and functional conservation of serotonin receptors throughout evolution. Experientia Supplementa 63, 266-278.
12. Hirsh, J. (1998). Decapitated Drosophila: a novel system for the study of biogenic amines. Advances in Pharmacology 42, 945-948.
13. Hoffmann, A. A., Hallas, R., Sinclair, C. & Mitrovski, P. (2001). Levels of variation in stress resistance in Drosophila among strains, local populations, and geographic regions: patterns for desiccation, starvation, cold resistance, and associated traits. Evolution 55, 1621-1630.
14. Itoyama, M. M., De Campos Bicudo, H. E. M. & Manzato, A. J. (1998). The development of resistance to caffeine in Drosophila prosaltans: productivity and longevity after ten generations of treatment. Cytobios 96, 81-93.
15. Johnson, E., Ringo, J., Bray, N. & Dowse, H. (1998). Genetic and pharmacological identification of ion channels central to the Drosophila cardiac pacemaker. Journal of Neurogenetics 12, 1-24.
16. Kearsey, M. J. & Pooni, H. S. (1996). The Genetical Analysis of Quantitative Traits. New York: Chapman and Hall.
17. Kennington, W. J., Gilchrist, A. S., Goldstein, D. B. & Partridge, L. (2001). The genetic bases of divergence in desiccation and starvation resistance among tropical and temperate populations of Drosophila melanogaster. Heredity 87, 363-372.
18. McLeod, H. L. & Evans, W. E. (2001). Pharmacogenomics: unlocking the human genome for better drug therapy. Annual Review of Pharmacology and Toxicology 41, 101-121.
19. Osborne, K. A., Robichon, A., Burgess, E., Butland, S., Shaw, R., Coulthard, A., Pereira, H. S., Greenspan, R. J. & Sokolowski, M. B. (1997). Natural behavior polymorphism due to a cGMP-dependent protein kinase of Drosophila. Science 277, 834-836.
20. Pietila, K. & Ahtee, L. (2000). Chronic nicotine administration in the drinking water affects the striatal dopamine in mice. Pharmacology Biochemistry and Behavior 66, 95-103.
21. Robbins, J., Aggarwal, R., Nichols, R. & Gibson, G. (1999). Genetic variation affecting heart rate in Drosophila melanogaster. Genetical Research 74, 121-128.
22. Robertson, A. (1959). The sampling variance of the genetic correlation coefficient. Biometrics 15, 469-485.
23. SAS Institute (1995). SAS/STAT User's Guide. Cary, NC: SAS Institute.
24. Sokolowski, M. B. (2001). Drosophila: genetics meets behavior. Nature Reviews Genetics 2, 879-890.
25. Walker, R. J., Brooks, H. L. & Holden-Dye, L. (1996). Evolution and overview of classical transmitter molecules and their receptors. Parasitology 113, S3-S33.
26. Zimmering, S., Kofkoff, R. & Osgood, C. (1977). Survival of caffeine-fed adult males and females from strains of Drosophila melanogaster. Mutation Research 43, 453-456.