Glucose is required to maintain high ATP-levels for the energy-utilizing steps during PDT-induced apoptosis

Photochemistry and Photobiology

Volumn 76, Issue 6, 2002, Pages 695-703

  Oberdanner, Christian Benno ^a   Kiesslich, Tobias ^a   Krammer, Barbara ^a   Plaetzer, Kristjan ^a  

^a UNIVERSITY OF SALZBURG   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CASPASE 3; TETRASULFOPHTHALOCYANINE ALUMINUM;

APOPTOSIS; ARTICLE; CARBOHYDRATE ANALYSIS; CELL ASSAY; CELL LEVEL; CELL NUCLEUS; CONTROLLED STUDY; ENERGY; ENERGY RESOURCE; ENZYME ACTIVATION; GLYCOLYSIS; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; MONITORING; PHOTODYNAMIC THERAPY; SQUAMOUS CELL CARCINOMA;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; CASPASE 3; CASPASES; DNA FRAGMENTATION; GLUCOSE; GLYCOLYSIS; HUMANS; INDOLES; MEMBRANE POTENTIALS; MITOCHONDRIA; ORGANOMETALLIC COMPOUNDS; PHOTOCHEMOTHERAPY; RADIATION-SENSITIZING AGENTS; SKIN NEOPLASMS; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0036985057     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1562/0031-8655(2002)076<0695:GIRTMH>2.0.CO;2     Document Type: Article

References (57)

1. Kessel, D. and Y. Luo (1999) Photodynamic therapy: a mitochondrial inducer of apoptosis. Cell Death Differ. 6(1), 28-35.
2. Fabris, C., G. Valduga, G. Miotto, L. Borsetto, G. Jori, S. Garbisa and E. Reddi (2001) Photosensitization with zinc (II) phthalocyanine as a switch in the decision between apoptosis and necrosis. Cancer Res. 61(20), 7495-7500.
3. Sun, J., I. Cecic, C. S. Parkins and M. Korbelik (2002) Neutrophils as inflammatory and immune effectors in photodynamic therapy-treated mouse SCCVII tumours. Photochem. Photobiol. Sci. [First published On the web: 16th July 2002].
4. Reiter, I., B. Krammer and G. Schwamberger (1999) Cutting edge: differential effect of apoptotic Versus necrotic tumor cells on macrophage antitumor activities. J. Immunol. 163(4), 1730-1732.
5. Fadok, V. A., D. L. Bratton, L. Guthrie and P. M. Henson (2001) Differential effects of apoptotic versus lysed cells on macrophage production of cytokines: role of proteases. J. Immunol. 166(1 l), 6847-6854.
6. Oleinick, N. L., R. L. Morris and I. Belichenko (2002) The role of apoptosis in response to photodynamic therapy: what, where, why, and how. Photochem. Photobiol. Sci. 1(1), 1-21.
7. Agárwal, M. L., M. E. Clay, E. J. Harvey, H. H. Evans, A. R. Antunez and N. L. Oleinick (1991) Photodynamic therapy induces rapid cell death by apoptosis in L5178Y mouse lymphoma cells. Cancer Res. 51(21), 5993-5996.
8. Ruck, A., K. Heckelsmiller, R. Kaufmann, N. Grossman, E. Haseroth and N. Akgun (2000) Light-induced apoptosis involves a defined sequence of cytoplasmic and nuclear calcium release in A1PcS4-photosensitized rat bladder RR 1022 epithelial cells. Photochem. Photobiol. 72(2), 210-216.
9. Zaidi, S. I., N. L. Oleinick, M. T. Zaim and H. Mukhtar (1993) Apoptosis during photodynamic therapy-induced ablation of RIF-1 tumors in C3H mice: electron microscopic histopathologic and biochemical evidence. Photochem. Photobiol. 58(6), 771-776.
10. Leist, M., B. Single, A. F. Castoldi, S, Kuhnle and P. Nicotera (1997) Intracellular aderiosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis, J. Exp. Med. 185(8), 1481-1486.
11. Nicotera, P., M. Leist and E. FerrandoMay (1998) Intracellular ATP, a switch in the decision between apoptosis and necrosis. Toxicol. Lett. 103, 139-142.
12. Eguchi, Y., S. Shimizu and Y. Tsujimöto (1997) Intracellular ATP levels determine cell death late by apoptosis or necrosis. Cancer Res. 57(10), 1835-1840.
13. Plaetzer, K., T. Kiesslich, B. Krammer and P. Hammerl (2002) Characterization of the cell death modes and the associated changes in cellular energy supply in response to A1PcS4-PDT. Photochem. Photobiol. Sci. 1(3), 172-177.
14. Liu, X., C. N. Kim, J. Yang, R. Jemmerson and X. Wang (1996) Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86(1), 147-157.
15. Hu, Y., M. A. Benedict, L. Ding and G. Nunez (1999) Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis. Embo J. 18(13) 3586-3595.
16. Saleh, A., S. M. Srinivasula, S. Acharya, R. Fishel and E. S. Alnemri (1999) Cytochrome c and dATP-mediated ollgomerization of Apaf-1 is a prerequisite for procaspase-9 activation. J. Biol. Chem. 274(25), 17941-17945.
17. Zou, H., Y, Li, X. Liu and X. Wang (1999) An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J. Biol. Chem. 274(17), 11549-11556.
18. Eguchi, Y., A. Srinivasan, K. J. Tomaselli, S. Shimizu and Y. Tsujimoto (1999) ATP-dependent steps in apoptotic signal transduction. Cancer Res. 59(9), 2174-2181.
19. Yasuhara, N., Y. Eguchi, T. Tachibana, N. Imamoto, Y. Yoneda and Y. Tsujimoto (1997) Essential role of active nuclear transport in apoptosis. Genes Cells 2(1), 55-64.
20. Mills, J. C., N. L. Stone and R. N. Pittman (1999) Extranuclear apoptosis. The role of the cytoplasm in the execution phase. J. Cell Biol. 146(4), 703-708.
21. Skulachev, V. P. (1999) Mitochondrial physiology and pathology; concepts of programmed death of organelles, cells and organisms. Mol. Aspects Med. 20(3), 139-184.
22. Mitchell, P. (1966) Chemiosmotic coupling in oxidative and photosynthetic phosphorylation. Biol. Rev. Camb. Philos. Soc. 41(3), 445-502.
23. Heiskanen, K. M., M. B. Bhat, H. W. Wang, J. Ma and A. L. Nieminen (1999) Mitochondrial depolarization accompanies cytochrome c release during apoptosis in PC6 cells. J. Biol. Chem. 274(9), 5654-5658.
24. Scarlett, J. L., P. W. Sheard, G. Hughes, E. C. Ledgerwood, H. H. Ku and M. P. Murphy (2000) Changes in mitochondrial membrane potential during staurosporine-induced apoptosis in Jurkat cells. FEBS Lett. 475(3), 267-272.
25. Skulachev, V. P. (1988) Membrane Bioenergetics. Springer-Verlag, Berlin.
26. Tiefenthaler, M., A. Amberger, N. Bacher, B. L. Hartmann, R. Margreiter, R. Kofler and G. Konwalinka (2001) Increased lactate production follows loss of mitochondrial membrane potential during apoptosis of human leukaemia cells. Br. J. Haematol. 114(3), 574-580.
27. Stridh, H., E. Fava, B. Single, P. Nicotera, S. Orrenius and M. Leist (1999) Tributyltin-induced apoptosis requires glycolytic adenosine trisphosphate production. Chem. Res. Toxicol. 12(10), 874-882.
28. Meisenholder, G. W., S. J. Martin, D. R. Green, J. Nordberg, B. M. Babior and R. A. Gottlieb (1996) Events in apoptosis. Acidification is downstream of protease activation and BCL-2 protection. J. Biol. Chem. 271(27), 16260-16262.
29. Hirpara, J. L., M. V. Clement and S. Pervaiz (2001) Intracellular acidification triggered, by mitochondrial-derived hydrogen peroxide is an effector mechanism for drag-induced apoptosis in tumor cells. J. Biol. Chem. 276(1), 514-521.
30. Gottlieb, R. A., J. Nordberg, E. Skowronski and B. M. Babior (1996) Apoptosis induced in Jurkat cells by several agents is preceded by intracellular acidification. Proc. Natl. Acad. Sci. USA 93(2), 654-658.
31. Gottlieb, R. A., H. A. Giesing, J. Y. Zhu, R. L. Engler and B. M. Babior (1995) Cell acidification in apoptosis: granulocyte colony-stimulating factor delays programmed cell death in neutrophils by up-regulating the vacuolar H(+)-ATPase. Proc. Natl. Acad. Sci. USA 92(13), 5965-5968.
32. Nicholson, D. W. (1999) Caspase structure, proteolytic substrates, and function during apoptotic cell death. Cell Death Differ. 6(11), 1028-1042.
33. Earnshaw, W. C., L. M. Martins and S. H. Kaufmann (1999) Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu. Rev. Biochem. 68, 383-424.
34. Ball, D. J., S. Mayhew, D. I. Vernon, M. Griffin and S. B. Brown (2001) Decreased efficiency of trypsinization of cells following photodynamic therapy: evaluation of a role for tissue transglutaminase. Photochem. Photobiol. 73(1), 47-53.
35. Smith, P. K., R. I. Krohn, G. T. Hermanson, A. K. Mallia, F. H. Gartner, M. D. Provenzano, E. K. Fujimoto, N. M. Goeke, B. J. Olson and D. C. Klenk (1985) Measurement of protein using bicinchoninic acid. Anal. Biochem. 150(1), 76-85.
36. Bernardi, P., L. Scorrano, R. Colonna, V. Petronilli and F. Di Lisa (1999) Mitochondria and cell death. Mechanistic aspects and methodological issues. Eur. J. Biochem. 264(3), 687-701.
37. Ormerod, M. G. (2002) Investigating the relationship between the cell cycle and apoptosis using flow cytometry. J. Immunol. Methods 265(1-2), 73-80.
38. Vermes, I., C. Haanen and C. Reutelingsperger (2000) Flow cytometry of apoptotic cell death. J. Immunol. Methods 243(1-2), 167-190.
39. Neufeld, H. A., R. D. Towner and J. Pace (1975) A rapid method for determining ATP by the firefly luciferin-luciferase system. Experientia 31(3), 391-392.
40. Ford, S. R. and F. R. Leach (1998) Bioluminescent assay of the adenylate energy charge. Methods Mol. Biol. 102, 69-81.
41. Hampp, R. (1985) Luminometric method. In Methods of Enzymatic Analysis, Metabolites 2, (Edited by M. Grassl); pp. 370-379. VCH, Weinheim.
42. Reers, M., T. W. Smith and L. B. Chen (1991) J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential. Biochemistry 30(18), 4480-4486.
43. Smiley, S. T., M. Reers, C. Mottola-Hartshom, M. Lin, A. Chen, T. W. Smith, G. D. Steele, Jr. and L. B. Chen (1991) Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc. Natl. Acad. Sci. USA 88(9), 3671-3675.
44. Chiu, S. M. and N. L. Oleinick (2001) Dissociation of mitochondrial depolarization from cytochrome c release during apoptosis induced by photodynamic therapy. Br. J. Cancer 84(8), 1099-1106.
45. Salvioli, S., A. Ardizzoni, C. Franceschi and A. Cossarizza (1997) JC-1, but not DiOC(6)(3) or rhodamine 123, is a reliable fluorescent probe to assess Delta Psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. FEBS Lett. 411(1), 77-82.
46. Kass, G. E., J. E. Eriksson, M. Weis, S. Orrenius and S. C. Chow (1996) Chromatin condensation during apoptosis requires ATP. Biochem. J. 318(Pt 3), 749-752.
47. McConkey, D. J. (1998) Biochemical determinants of apoptosis and necrosis. Toxicol. Lett. 99(3), 157-168.
48. Genini, D., I. Budihardjo, W. Plunkett, X. Wang, C. J. Carrera, H. B. Cottam, D. A. Carson and L. M. Leoni (2000) Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway. J. Biol. Chem. 275(1), 29-34.
49. Daugas, E., S. A. Susin, N. Zamzami, K. F. Ferri, T. Irinopoulou, N. Larochette, M. C. Prevost, B. Leber, D. Andrews, J. Penninger and G. Kroemer (2000) Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis. Faseb. J. 14(5), 729-739.
50. Daugas, E., D. Nochy, L. Ravagnan, M. Loeffler, S. A. Susin, N. Zamzami and G. Kroemer (2000) Apoptosis-inducing factor (ALF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis. FEBS Lett. 476(3), 118-123.
51. Joza, N., S. A. Susin, E. Daugas, W. L. Stanford, S. K. Cho, C. Y. Li, T. Sasaki, A. J. Elia, H. Y. Cheng, L. Ravaghan, K. F. Ferri, N. Zamzami, A. Wakeham, R. Hakem, H. Yoshida, Y. Y. Kong, T. W. Mak, J. C. Zuniga-Pflucker, G. Kroemer and J. M. Penninger (2001) Essential role of tile mitochondrial apoptosis-inducing factor in programmed cell death. Nature 410(6828), 549-554.
52. Loeffler, M., E. Daugas, S. A. Susin, N. Zamzami, D. Metivier, A. L. Nieminen, G. Brothers, J. M. Penninger and G. Kroemer (2001) Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor. Faseb. J. 15(3), 758-767.
53. Susin, S. A., H. K. Lorenzo, N. Zamzami, I. Marzo, B. E. Snow. G. M. Brothers, J. Mangion, E. Jacotot, P. Costantini, M. Loeffler, N. Larochette, D. R. Goodlett, R. Aebersold, D. P. Siderovski, J. M. Penninger and G. Kroemer (1999) Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397(6718), 441-446.
54. Hacker, G. (2000) The morphology of apoptosis. Cell Tissue Res. 301(1), 5-17.
55. Thakkar, N. S. and C. S. Potten (1993) Inhibition of doxorubicin-induced apoptosis in vivo by 2-deoxy-D-glucose. Cancer Res. 53(9), 2057-2060.
56. Sauter, B., M. L. Albert, L. Francisco, M. Larsson, S. Somersan and N. Bhardwaj (2000) Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J. Exp. Med. 191(3), 423-434.
57. Martin, D. S., D. Spriggs and J. A. Koutcher (2001) A concomitant ATP-depleting strategy markedly enhances anticancer agent activity. Apoptosis 6(1-2), 125-131.