1-Methoxy-, 1-deoxy-11-hydroxy- and 11-hydroxy-1-methoxy-Δ8-tetrahydrocannabinols: New selective ligands for the CB2 receptor

Bioorganic and Medicinal Chemistry

Volumn 10, Issue 12, 2002, Pages 4119-4129

  Huffman, John W ^a   Bushell, Simon M ^a   Miller, John R A ^a   Wiley, Jenny L ^b   Martin, Billy R ^b  

^a CLEMSON UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 DEOXY 11 HYDROXY 3 8DELTA TETRAHYDROCANNABINOL; 1 DEOXY 3 (1',1' DIMETHYLBUTYL) 11 HYDROXY 8DELTA TETRAHYDROCANNABINOL; 1 DEOXY 3 (1',1' DIMETHYLETHYL) 11 HYDROXY 8DELTA TETRAHYDROCANNABINOL; 1 DEOXY 3 (1',1' DIMETHYLHEXYL) 11 HYDROXY 8DELTA TETRAHYDROCANNABINOL; 1 DEOXY 3 (1',1' DIMETHYLPENTYL) 11 HYDROXY 8DELTA TETRAHYDROCANNABINOL; 1 DEOXY 3 (1',1' DIMETHYLPROPYL) 11 HYDROXY 8DELTA TETRAHYDROCANNABINOL; 1 METHOXY 3 (1',1' DIMETHYLBUTYL) 11 HYDROXY 8DELTA TETRAHYDROXYCANNABINOL; 1 METHOXY 3 (1',1' DIMETHYLBUTYL) 8DELTA TETRAHYDROCANNABINOL; 1 METHOXY 3 (1',1' DIMETHYLETHYL) 11 HYDROXY 8DELTA TETRAHYDROXYCANNABINOL; 1 METHOXY 3 (1',1' DIMETHYLETHYL) 11 PIVALOYLOXY 8DELTA TETRAHYDROXYCANNABINOL; 1 METHOXY 3 (1',1' DIMETHYLETHYL) 8DELTA TETRAHYDROCANNABINOL; 1 METHOXY 3 (1',1' DIMETHYLHEXYL) 11 HYDROXY 8DELTA TETRAHYDROXYCANNABINOL; 1 METHOXY 3 (1',1' DIMETHYLHEXYL) 11 OXO 8DELTA TETRAHYDROXYCANNABINOL; 1 METHOXY 3 (1',1' DIMETHYLHEXYL) 8DELTA TETRAHYDROCANNABINOL; 1 METHOXY 3 (1',1' DIMETHYLPENTYL) 11 HYDROXY 8DELTA TETRAHYDROXYCANNABINOL; 1 METHOXY 3 (1',1' DIMETHYLPENTYL) 11 OXO 8DELTA TETRAHYDROXYCANNABINOL; 1 METHOXY 3 (1',1' DIMETHYLPENTYL) 8DELTA TETRAHYDROCANNABINOL; 1 METHOXY 3 (1',1' DIMETHYLPROPYL) 11 HYDROXY 8DELTA TETRAHYDROXYCANNABINOL; 1 METHOXY 3 (1',1' DIMETHYLPROPYL) 11 PIVALOYLOXY 8DELTA TETRAHYDROXYCANNABINOL; 1 METHOXY 3 (1',1' DIMETHYLPROPYL) 8DELTA TETRAHYDROCANNABINOL; 1 METHOXY 3 8DELTA TETRAHYDROCANNABINOL; 11 HYDROXY 1 METHOXY 3 8DELTA TETRAHYDROCANNABINOL; 3 (1',1' DIMETHYLBUTYL) 1 METHOXY 11 OXO 8DELTA TETRAHYDROXYCANNABINOL; 3 (1',1' DIMETHYLETHYL) 11 PIVALOYLOXY 8DELTA TETRAHYDROXYCANNABINOL; 3 (1',1' DIMETHYLPROPYL) 11 PIVALOYLOXY 8DELTA TETRAHYDROCANNABINOL; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; LIGAND; TETRAHYDROCANNABINOL DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; DRUG SYNTHESIS; HUMAN; RECEPTOR AFFINITY;

ANIMALS; BRAIN CHEMISTRY; CELL LINE; HUMANS; LIGANDS; MICE; RADIOLIGAND ASSAY; RECEPTORS, CANNABINOID; RECEPTORS, DRUG; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAHYDROCANNABINOL;

EID: 0036973491     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(02)00331-0     Document Type: Article

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