-
3
-
-
0022885592
-
-
Razdan, R.K. Pharmacol. Rev., 1986, 38, 75; Devane, W.A.; Breuer, A.; Sheskin, T.; Järbe, T.U.C.; Eisen, M.S.; Mechoulam, R. J. Med. Chem., 1992, 35, 2065.
-
(1986)
Pharmacol. Rev.
, vol.38
, pp. 75
-
-
Razdan, R.K.1
-
4
-
-
0026715999
-
-
Razdan, R.K. Pharmacol. Rev., 1986, 38, 75; Devane, W.A.; Breuer, A.; Sheskin, T.; Järbe, T.U.C.; Eisen, M.S.; Mechoulam, R. J. Med. Chem., 1992, 35, 2065.
-
(1992)
J. Med. Chem.
, vol.35
, pp. 2065
-
-
Devane, W.A.1
Breuer, A.2
Sheskin, T.3
Järbe, T.U.C.4
Eisen, M.S.5
Mechoulam, R.6
-
5
-
-
0027515373
-
-
Munro, S.; Thomas, K. L.; Abu-Shaar, M. Nature, 1993, 365, 61.
-
(1993)
Nature
, vol.365
, pp. 61
-
-
Munro, S.1
Thomas, K.L.2
Abu-Shaar, M.3
-
6
-
-
0025325535
-
-
Matsuda, L.A.; Lolait, S.J.; Brownstein, M.J.; Young, A.C.; Bonner, T.I. Nature, 1990,346, 561.
-
(1990)
Nature
, vol.346
, pp. 561
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, A.C.4
Bonner, T.I.5
-
7
-
-
85031210530
-
-
note
-
Satisfactory analytical data for all compounds have been obtained.
-
-
-
-
9
-
-
0027225185
-
-
Reggio, P.H.; Panu, A.M.; Miles, S. J. Med. Chem., 1993, 36, 1761; Adams, R.; Harfenst, M.; Lowe, S. J. Amer. Chem. Soc. 1949, 71, 1624.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 1761
-
-
Reggio, P.H.1
Panu, A.M.2
Miles, S.3
-
10
-
-
0001065345
-
-
Reggio, P.H.; Panu, A.M.; Miles, S. J. Med. Chem., 1993, 36, 1761; Adams, R.; Harfenst, M.; Lowe, S. J. Amer. Chem. Soc. 1949, 71, 1624.
-
(1949)
J. Amer. Chem. Soc.
, vol.71
, pp. 1624
-
-
Adams, R.1
Harfenst, M.2
Lowe, S.3
-
11
-
-
0019827653
-
-
Martin, B.R.; Balster, R.L.; Razdan, R.K.; Harris, L.S.; Dewey, W.I. Life Sciences; 1981, 29, 565; Mechoulam, R.; Lander, N.; Breuer, A.; Zahalka, J. Tetrahedron: Asymmetry, 1990, 1, 315.
-
(1981)
Life Sciences
, vol.29
, pp. 565
-
-
Martin, B.R.1
Balster, R.L.2
Razdan, R.K.3
Harris, L.S.4
Dewey, W.I.5
-
12
-
-
0024986448
-
-
Martin, B.R.; Balster, R.L.; Razdan, R.K.; Harris, L.S.; Dewey, W.I. Life Sciences; 1981, 29, 565; Mechoulam, R.; Lander, N.; Breuer, A.; Zahalka, J. Tetrahedron: Asymmetry, 1990, 1, 315.
-
(1990)
Tetrahedron: Asymmetry
, vol.1
, pp. 315
-
-
Mechoulam, R.1
Lander, N.2
Breuer, A.3
Zahalka, J.4
-
13
-
-
0000976413
-
-
Brown, H.C.; Joshi, N.N. J. Org. Chem., 1988, 53, 4059. Both enantiomers are now commercially available at 97% ee.
-
(1988)
J. Org. Chem.
, vol.53
, pp. 4059
-
-
Brown, H.C.1
Joshi, N.N.2
-
14
-
-
0017780258
-
-
(a) Dominianni, S.J.; Ryan, C.W.; DeArmitt, C.W. J. Org. Chem., 1977, 42, 344.
-
(1977)
J. Org. Chem.
, vol.42
, pp. 344
-
-
Dominianni, S.J.1
Ryan, C.W.2
DeArmitt, C.W.3
-
15
-
-
37049130615
-
-
(b) Cooper, M.A.; Salmon, J.R.; Whittaker, D.; Scheidegger, U. J. Chem. Soc. (B), 1967, 1259.
-
(1967)
J. Chem. Soc. (B)
, pp. 1259
-
-
Cooper, M.A.1
Salmon, J.R.2
Whittaker, D.3
Scheidegger, U.4
-
17
-
-
0026671288
-
-
(d) Burstein, S.H.; Audette, C.A.; Breuer, A.; Devane, W.A.; Colodner, S.; Doyle, S.A.; Mechoulam, R. J. Med. Chem., 1992, 55, 3135
-
(1992)
J. Med. Chem.
, vol.55
, pp. 3135
-
-
Burstein, S.H.1
Audette, C.A.2
Breuer, A.3
Devane, W.A.4
Colodner, S.5
Doyle, S.A.6
Mechoulam, R.7
-
18
-
-
0015520848
-
-
(e) The same procedure was used for the preparation of the DMH as for the preparation of the pentyl chain: Mechoulam, R.; Braun, P.; Gaoni, Y. J. Amer. Chem. Soc., 1972, 94, 6159;.
-
(1972)
J. Amer. Chem. Soc.
, vol.94
, pp. 6159
-
-
Mechoulam, R.1
Braun, P.2
Gaoni, Y.3
-
20
-
-
0015220609
-
-
We used the procedure described for a similar compound by: Wildes, J.W.; Martin, N.H.; Pitt, C.G.; Wall, M.E. J. Org. Chem., 1971, 36, 721.
-
(1971)
J. Org. Chem.
, vol.36
, pp. 721
-
-
Wildes, J.W.1
Martin, N.H.2
Pitt, C.G.3
Wall, M.E.4
-
21
-
-
0001850107
-
-
Edery, H.; Grunfeld, Y.; Ben-Zvi, Z.; Mechoulam, R. Ann. N.Y. Acad. Sci. 1971, 191, 40; Reggio, P.H.; Seltzman, H.H.; Compton, D.R.; Prescott, Jr, W.R.; Martin, B.R. Mol. Pharmacol. 1990, 38, 854.
-
(1971)
Ann. N.Y. Acad. Sci.
, vol.191
, pp. 40
-
-
Edery, H.1
Grunfeld, Y.2
Ben-Zvi, Z.3
Mechoulam, R.4
-
22
-
-
0025672569
-
-
Edery, H.; Grunfeld, Y.; Ben-Zvi, Z.; Mechoulam, R. Ann. N.Y. Acad. Sci. 1971, 191, 40; Reggio, P.H.; Seltzman, H.H.; Compton, D.R.; Prescott, Jr, W.R.; Martin, B.R. Mol. Pharmacol. 1990, 38, 854.
-
(1990)
Mol. Pharmacol.
, vol.38
, pp. 854
-
-
Reggio, P.H.1
Seltzman, H.H.2
Compton, D.R.3
Prescott W.R., Jr.4
Martin, B.R.5
-
23
-
-
85031223377
-
-
note
-
3 according to ref. 10a.
-
-
-
-
24
-
-
85031218959
-
-
note
-
Compound 6 was prepared by treatment of 1 with diethyl chlorophosphonate according to ref. 10a.
-
-
-
-
25
-
-
0025876678
-
-
Huffman, J.W.; Joyner, H.H.; Lee, M.D.; Jordan, R.D.; Pennington, W.T. J. Org. Chem., 1991, 56, 2081.
-
(1991)
J. Org. Chem.
, vol.56
, pp. 2081
-
-
Huffman, J.W.1
Joyner, H.H.2
Lee, M.D.3
Jordan, R.D.4
Pennington, W.T.5
-
26
-
-
0027430992
-
-
CP-55940 is a non-tricyclic ring system. Melvin, L.S.; Milne, G.M.; Johnson, M.R.; Subramaniam, B.; Wilken, G.H.; Howlett, A.C. Mol. Pharmacol. 1994, 44, 1008.
-
(1994)
Mol. Pharmacol.
, vol.44
, pp. 1008
-
-
Melvin, L.S.1
Milne, G.M.2
Johnson, M.R.3
Subramaniam, B.4
Wilken, G.H.5
Howlett, A.C.6
-
27
-
-
85031230874
-
-
1981 Canadian Patent, 1 114 828
-
Mechoulam, R.; Lander, N.; Dikstein, S.; Shalita, B.; 1981 Canadian Patent, 1 114 828.
-
-
-
Mechoulam, R.1
Lander, N.2
Dikstein, S.3
Shalita, B.4
-
29
-
-
0025230635
-
-
Fu, J.; Snieckus, V. Tetrahedron Lett., 1990, 31, 1665. Alo, B.I.; Kandil, A.; Paul, P.A.; Sharp, M.J.; Siddiqui, M.A.; Snieckus, V. J. Org. Chem., 1991, 56, 3763.
-
(1990)
Tetrahedron Lett.
, vol.31
, pp. 1665
-
-
Fu, J.1
Snieckus, V.2
-
30
-
-
0025816845
-
-
Fu, J.; Snieckus, V. Tetrahedron Lett., 1990, 31, 1665. Alo, B.I.; Kandil, A.; Paul, P.A.; Sharp, M.J.; Siddiqui, M.A.; Snieckus, V. J. Org. Chem., 1991, 56, 3763.
-
(1991)
J. Org. Chem.
, vol.56
, pp. 3763
-
-
Alo, B.I.1
Kandil, A.2
Paul, P.A.3
Sharp, M.J.4
Siddiqui, M.A.5
Snieckus, V.6
|