Distinct role of nitric oxide and endothelium-derived hyperpolarizing factor in renal microcirculation: Studies in the isolated perfused hydronephrotic kidney

Nephron

Volumn 92, Issue 4, 2002, Pages 905-913

  Ozawa, Yuri ^a   Hayashi, Koichi ^a   Nagahama, Takahiko ^a   Fujiwara, Keiji ^a   Kanda, Takeshi ^a   Homma, Koichiro ^a   Saruta, Takao ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

Afferent arteriole; Interlobular artery; Nitric oxide; Renal microcirculation; WEndothelium derived hyperpolarizing factor

Indexed keywords

ACETYLCHOLINE; APAMIN; CHARYBDOTOXIN; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NORADRENALIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIOLE; ARTERY DILATATION; ARTICLE; BLOOD VESSEL DIAMETER; BLOOD VESSEL TONE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DATA ANALYSIS; HYDRONEPHROSIS; KIDNEY CIRCULATION; MALE; MICROCIRCULATION; NONHUMAN; PRIORITY JOURNAL; RAT; VASOCONSTRICTION;

ACETYLCHOLINE; ANIMALS; APAMIN; ARTERIES; BIOLOGICAL FACTORS; CHARYBDOTOXIN; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HYDRONEPHROSIS; KIDNEY; MALE; MICROCIRCULATION; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NOREPINEPHRINE; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; RATS; RATS, WISTAR; VASOCONSTRICTOR AGENTS; VASODILATION; VASODILATOR AGENTS;

EID: 0036967207     PISSN: 00282766     EISSN: None     Source Type: Journal    
DOI: 10.1159/000065460     Document Type: Article

References (29)

1. Furchgott RF: The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980;288: 373-376.
2. Beetens JR, van Hove C, Rampart M, Herman AG: Acetylcholine stimulates the release of prostacyclin by rabbit aorta endothelium. J Pharm Pharmacol 1983;35:251-252.
3. Hecker M, Bara AT, Bauersachs J, Busse R: Characterization of endothelium-derived hyperpolarizing factor as a cytochrome P450-derived arachidonic acid metabolite in mammals. J Physiol 1994;481:407-414.
4. Ito S, Johnson CS, Carretero OA: Modulation of angiotensin II-induced vasoconstriction by endothelium-derived relaxing factor in the isolated microperfused rabbit afferent arteriole. J Clin Invest 1991;87:1656-1663.
5. Hayashi K, Epstein M, Loutzenhiser R: Enhanced myogenic responsiveness of renal interlobular arteries in spontaneously hypertensive rats. Hypertension 1992;19:153-160.
6. Ito S, Juncos LA, Nushiro N, Johnson CS, Carretero OA: Endothelium-derived relaxing factor modulates endothelin action in afferent arterioles. Hypertension 1992;17:1052-1056.
7. Arima S, Endo Y, Yaoita H, Omata K, Ogawa S, Tsunoda K, Abe M, Takeuchi K, Abe K, Ito S: Possible role of P-450 metabolite of arachidonic acid in vasodilator mechanism of angiotensin II type 2 receptor in the isolated microperfused rabbit afferent arteriole. J Clin Invest 1997;100:2816-2823.
8. Hayashi K, Loutzenhiser R, Epstein M, Suzuki H, Saruta T: Multiple factors contribute to acetylcholine-induced renal afferent arteriolar vasodilation during myogenic and norepinephrine- and KCl-induced vasoconstriction: Studies in the isolated perfused hydronephrotic kidney. Circ Res 1994;75:821-828.
9. Hayashi K, Matsuda H, Nagahama T, Fujiwara K, Ozawa Y, Kubota E, Honda M, Tokuyama H, Saruta T: Impaired nitric oxide-independent dilation of renal afferent arterioles in spontaneously hypertensive rats. Hypertens Res 1999;2:31-33.
10. Takenaka T, Suzuki H, Okada H, Hayashi K, Ozawa Y, Saruta T: Biophysical signals underlying myogenic responses in rat interlobular artery. Hypertension 1998;32:1060-1065.
11. Urakami-Harasawa L, Shimokawa H, Nakashima M, Egashira K, Takeshita A: Importance of endothelium-derived hyperpolarizing factor in human arteries. J Clin Invest 1997;100:2793-2799.
12. Nishikawa Y, Stepp DW, Chilian WM: In vivo location and mechanism of EDHF-mediated vasodilation in canine coronary microcirculation. Am J Physiol 1999;277:H1252-H1259.
13. Loutzenhiser R, Hayashi K, Epstein M: Atrial natriuretic peptide reverses afferent arteriolar vasoconstriction and potentiates efferent arteriolar vasoconstriction in the isolated perfused rat kidney. J Pharmacol Exp Ther 1988;246: 522-528.
14. Loutzenhiser R, Hayashi K, Epstein M: Divergent effects of KCl-induced depolarization on afferent and efferent arterioles. Am J Physiol 1989;257:F561-F564.
15. + channels in mediating heterogeneous microvascular responses to acetylcholine in different vascular beds. J Pharmacol Exp Ther 1997;282:1473-1479.
16. Zygmunt PM, Hogestatt ED: Role of potassium channels in endothelium-dependent relaxation resistant to nitroarginine in the rat hepatic artery. Br J Pharmacol 1996;117:1600-1606.
17. Epstein M, Flamenbaum W, Loutzenhiser R: Characterization of the renin-angiotensin system in the isolated perfused kidney. Renal Physiol 1980;2:244-256.
18. Navar LG: Integrating multiple paracrines regulators of renal microvascular dynamics. Am J Physiol 1998;274:F433-F444.
19. Campbell WB, Gebremedhin D, Pratt PF, Harder DR: Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors. Circ Res 1996;78:415-423.
20. Cowan CL, Palacino JJ, Najibi S, Cohen RA: Potassium channel-mediated relaxation to acetylcholine in rabbit arteries. J Pharmacol Exp Ther 1993;266:1482-1489.
21. Roman RJ, Maier KG, Sun C-W, Harder DR, Alonso-Galicia M: Renal and cardiovascular actions of 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids. Clin Exp Pharmacol Physiol 2000;27:855-865.
22. Feletou M, Vanhoutte PM: Endothelium-dependent hyperpolarization of vascular smooth muscle cells. Acta Pharmacol Sin 2000;21:1-18.
23. Fujii K, Tominaga M, Ohmori S, Kobayashi K, Koga T, Takata Y, Fujishima M: Decreased endothelium-dependent hyperpolarization to acetylcholine in smooth muscle of the mesenteric artery of spontaneously hypertensive rats. Circ Res 1992;70:660-669.
24. Shimokawa H, Yasutake H, Fujii K, Owada MK, Nakaike R, Fukumoto Y, Takayanagi T, Nagao I, Egashira K, Fujishima M, Takeshita A: The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation. J Cardiovasc Pharmacol 1996;28:703-711.
25. Zygmunt PM, Ryman T, Hogestatt ED: Regional differences in endothelium-dependent relaxation in the rat: Contribution of nitric oxide and nitric oxide-independent mechanisms. Acta Physiol Scand 1995;155:257-266.
26. Brayden JE: Membrane hyperpolarization is a mechanism of endothelium-dependent cerebral vasodilation. Am J Physiol 1990;259: H668-H673.
27. Fisslthaler B, Popp R, Kiss L, Potente M, Harder DR, Fleming I, Busse R: Cytochrome p450 2C is an EDHF synthase in coronary arteries. Nature 1999;401:493-497.
28. + is an endothelium-derived hyperpolarizing factor in rat arteries. Nature 1998;396:269-272.
29. Bauersachs J, Popp R, Hecker M, Sauer E, Fleming I, Busse R: Nitric oxide attenuates the release of endothelium-derived hyperpolarizing factor. Circulation 1996;94:3341-3347.