Integrating multiple paracrine regulators of renal microvascular dynamics

American Journal of Physiology - Renal Physiology

Volumn 274, Issue 3 43-3, 1998, Pages

  Navar, L Gabriel ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Angiotensin II; Arachidonic acid metabolites; Calcium channels; Extracellular adenosine 5' triphosphate; Nitric oxide; Renal autoregulation; Tubuloglomerular feedback mechanism

Indexed keywords

AUTOREGULATION; BLOOD VESSEL TONE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; ENDOTHELIUM CELL; FEEDBACK SYSTEM; GLOMERULUS CAPILLARY; HORMONAL REGULATION; HUMAN; HUMAN CELL; KIDNEY BLOOD FLOW; MACULA DENSA; PRIORITY JOURNAL; REVIEW; VASCULAR SMOOTH MUSCLE;

EID: 0031942974     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.1998.274.3.f433     Document Type: Review

References (101)

1. Arendshorst, W. J., and L. G. Navar. Renal circulation and glomerular hemodynamics. In: Diseases of the Kidney, edited by R. W. Schrier and C. W. Gottschalk. Boston: Little-Brown, 1997, p. 59-106.
2. Aukland, K., and A. H. Oien. Renal autoregulation: models combining tubuloglomerular feedback and myogenic response. Am. J. Physiol. 252 (Renal Fluid Electrolyte Physiol. 21): F768-F783, 1987.
3. Bachmann, S., H. M. Bosse, and P. Mundel. Topography of nitric oxide synthesis by localizing constitutive NO synthases in mammalian kidney. Am. J. Physiol. 268 (Renal Fluid Electrolyte Physiol. 37): F885-F898, 1995.
4. Bell, P. D., M. Franco, and L. G. Navar. Calcium as a mediator of tubuloglomerular feedback. Annu. Rev. Physiol. 49: 275-293, 1987.
5. Bell, P. D., L. G. Navar, D. W. Ploth, and C. B. McLean. Tubuloglomerular feedback responses during perfusion with nonelectrolyte solutions in the rat. Kidney Int. 18: 460-471, 1980.
6. Braam, B., K. D. Mitchell, H. A. Koomans, and L. G. Navar. Relevance of the tubuloglomerular feedback mechanism in pathophysiology. J. Am. Soc. Nephrol. 4: 1257-1274, 1993.
7. Briggs, J. P., and J. Schnermann. Macula densa control of renin secretion and glomerular vascular tone: Evidence for common cellular mechanisms. Renal Physiol. 9: 193-203, 1986.
8. Briggs, J. P., and J. Schnermann. Control of renin release and glomerular vascular tone by the juxtaglomerular apparatus. In: Hypertension: Pathophysiology, Diagnosis, and Management, edited by J. H. Laragh and B. M. Brenner. New York: Raven, 1995, p. 1359-1385.
9. 2+] in renal arterioles. Am. J. Physiol. 265 (Renal Fluid Electrolyte Physiol. 34): F677-F685, 1993.
10. Carmines, P. K., E. W. Inscho, and R. C. Gensure. Arterial pressure effects on preglomerular microvasculature of juxtamedullary nephrons. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F94-F102, 1990.
11. Carmines, P. K., K. D. Mitchell, and L. G. Navar. Effects of calcium antagonists on renal hemodynamics and glomerular function. Kidney Int. 41, Suppl. 36: S-43-S-48, 1992.
12. Carmines, P. K., and L. G. Navar. Disparate effects of Ca channel blockade on afferent and efferent arteriolar responses to ANG II. Am. J. Physiol. 256 (Renal Fluid Electrolyte Physiol. 25): F1015-F1020, 1989.
13. Casellas, D., and L. C. Moore. Autoregulation and tubuloglomerular feedback in juxtamedullary glomerular arterioles. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F660-F669, 1990.
14. Casellas, D., and L. C. Moore. Autoregulation of intravascular pressure in preglomerular juxtamedullary vessels. Am. J. Physiol. 264 (Renal Fluid Electrolyte Physiol. 33): F315-F321, 1993.
15. Casellas, D., and L. G. Navar. In vitro perfusion of juxtamedullary nephrons in rats. Am. J. Physiol. 246 (Renal Fluid Electrolyte Physiol. 15): F349-F358, 1984.
16. Conger, J. D., and S. A. FaIk. KCl and angiotensin responses in isolated rat renal arterioles: effects of diltiazem and low-calcium medium. Am. J. Physiol. 264 (Renal Fluid Electrolyte Physiol. 33): F134-F140, 1993.
17. D'Angelo, G., and G. A. Meininger. Transduction mechanisms involved in the regulation of myogenic activity. Hypertension 23: 1096-1105, 1994.
18. Fleming, J. T., N. Parekh, and M. Steinhausen. Calcium antagonists preferentially dilate preglomerular vessels of hydronephrotic kidney. Am. J. Physiol. 253 (Renal Fluid Electrolyte Physiol. 22): F1157-F1163, 1987.
19. Franco, M., P. D. Bell, and L. G. Navar. Evaluation of prostaglandins as mediators of tubuloglomerular feedback. Am. J. Physiol. 254 (Renal Fluid Electrolyte Physiol. 23): F642-F649, 1988.
20. Goormaghtigh, N. L'appareil neuromyo-arteriel juxtaglomerulaire du rein; ses reactions en pathologie et ses rapports avec le tube urinifere. C. R. Soc. Biol. 124: 293-296, 1937.
21. Gordon, E. L., J. D. Pearson, E. S. Dickinson, D. Moreau, and L. L. Slakey. The hydrolysis of extracellular adenine nucleotides by arterial smooth muscle cells. J. Biol. Chem. 264: 18986-18992, 1989.
22. Gottschalk, C. W., and M. Mylle. Micropuncture study of the mammalian urinary concentrating mechanism: Evidence for the countercurrent hypothesis. Am. J. Physiol. 196: 927-936, 1959.
23. Guyton, A. C., J. B. Langston, and G. Navar. Theory for renal autoregulation by feedback at the juxtaglomerular apparatus. Circ. Res. 14, 15, Suppl. 1: I-187-I-197, 1964.
24. Hall, J. E., A. C. Guyton, T. E. Jackson, T. G. Coleman, T. E. Lohmeier, and N. C. Trippodo. Control of glomerular filtration rate by renin-angiotensin system. Am. J. Physiol. 233 (Renal Fluid Electrolyte Physiol. 2): F366-F372, 1977.
25. Harder, D. R., R. Gilbert, and J. H. Lombard. Vascular muscle cell depolarization and activation in renal arteries on elevation of transmural pressure. Am. J. Physiol. 253 (Renal Fluid Electrolyte Physiol. 22): F778-F781, 1987.
26. Harris, R. C. The macula densa: recent developments. J. Hypertens. 14: 815-822, 1996.
27. Harris, R. C., J. A. McKanna, Y. Akai, H. R. Jacobson, R. N. Dubois, and M. D. Breyer. Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. J. Clin.Invest. 94: 2504-2510, 1994.
28. Harrison-Bernard, L. M., and L. G. Navar. Renal cortical and medullary microvascular blood flow autoregulation in rat. Kidney Int. 50, Suppl. 57: S23-S29, 1996.
29. 1 receptor in adult rat kidney using a monoclonal antibody. Am. J. Physiol. 273 (Renal Physiol. 42): F170-F177, 1997.
30. Hayashi, K., M. Epstein, and R. Loutzenhiser. Pressure-induced vasoconstriction of renal microvessels in normotensive and hypertensive rats. Studies in the isolated perfused hydronephrotic kidney. Circ. Res. 65: 1475-1484, 1989.
31. Hársing, L., S. Fonyódi, M. Kabát, and G. Y. Kövér. Effect of phlorizin and of mercurial diuretics on renal hemodynamics. Acta Physiol. 12: 363-371, 1957.
32. Heller, J., and V. Horacek. Autoregulation of superficial nephron function in the alloperfused dog kidney. Pflügers Arch. 382: 99-104, 1979.
33. Heller, J., and V. Horacek. The effect of two different calcium antagonists on the glomerular haemodynamics in the dog. Pflügers Arch. 415: 751-755, 1990.
34. Heyeraas, K. J., and K. Aukland. Interlobular arterial resistance: influence of renal arterial pressure and angiotensin II. Kidney Int. 31: 1291-1298, 1987.
35. Holstein-Rathlou, N.-H., and D. J. Marsh. Renal blood flow regulation and arterial pressure fluctuations: A case study in nonlinear dynamics. Physiol. Rev. 74: 637-681, 1994.
36. Horowitz, A., C. B. Menice, R. Laporte, and K. G. Morgan. Mechanisms of smooth muscle contraction. Physiol. Rev. 76: 967-1003, 1996.
37. Ibarrola, A. M., E. W. Inscho, R. C. Vari, and L. G. Navar. Influence of adenosine receptor blockade on renal function and renal autoregulation. J. Am. Soc. Nephrol. 2: 991-999, 1991.
38. Imig, J. D., and L. G. Navar. Afferent arteriolar response to arachidonic acid: involvement of metabolic pathways. Am. J. Physiol. 271 (Renal Fluid Electrolyte Physiol. 40): F87-F93, 1996.
39. Imig, J. D., L. G. Navar, R. J. Roman, K. K. Reddy, and J. R. Falck. Actions of epoxygenase metabolites on the preglomerular vasculature. J. Am. Soc. Nephrol. 7: 2364-2370, 1996.
40. Imig, J. D., A.-P. Zou, P. R. O. de Montellano, Z. Sui, and R. J. Roman. Cytochrome P-450 inhibitors alter afferent arteriolar responses to elevations in pressure. Am. J. Physiol. 266 (Heart Circ. Physiol. 35): H1879-H1885, 1994.
41. Imig, J. D., A.-P. Zou, D. E. Stec, D. R. Harder, J. R. Falck, and R. J. Roman. Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles. Am. J. Physiol. 270 (Regulatory Integrative Comp. Physiol. 39): R217-R227, 1996.
42. 2-purinoceptor activation. Am. J. Physiol. 271 (Renal Fluid Electrolyte Physiol. 40): F1077-F1085, 1996.
43. Inscho, E. W., M. J. Mason, A. C. Schroeder, P. C. Deichmann, K. D. Stiegler, and J. D. Imig. Agonist-induced calcium regulation in freshly isolated renal microvascular smooth muscle cells. J. Am. Soc. Nephrol. 8: 569-579, 1997.
44. Inscho, E. W., K. D. Mitchell, and L. G. Navar. Extracellular ATP in the regulation of renal microvascular function. FASEB J. 8: 319-328, 1994.
45. Inscho, E. W., K. Ohishi, A. K. Cook, T. P. Belott, and L. G. Navar. Calcium activation mechanisms in the renal microvascular response to extracellular ATP. Am. J. Physiol. 268 (Renal Fluid Electrolyte Physiol. 37): F876-F884, 1995.
46. Inscho, E. W., K. Ohishi, and L. G. Navar. Effects of ATP on pre- and postglomerular juxtamedullary microvasculature. Am. J. Physiol. 263 (Renal Fluid Electrolyte Physiol. 32): F886-F893, 1992.
47. Ito, S., O. A. Carretero, and R. D. Murray. Possible role of adenosine in the macula densa mechanism of renin release in rabbits. J. Clin. Invest. 76: 1412-1417, 1985.
48. Ito, S., and Y. Ren. Evidence for the role of nitric oxide in macula densa control of glomerular hemodynamics. J. Clin. Invest. 92: 1093-1098, 1993.
49. Kirchheim, H. R., H. Ehmke, E. Hackenthal, W. Lowe, and P. Persson. Autoregulation of renal blood flow, glomerular filtration rate and renin release in conscious dogs. Pflügers Arch. 410: 441-449, 1987.
50. Lee, M. W., and D. L. Severson. Signal transduction in vascular smooth muscle: diacylglycerol second messengers and PKC action. Am. J. Physiol. 267 (Cell Physiol. 36): C659-C678, 1994.
51. Loutzenhiser, R., L. Chilton, and G. Trottier. Membrane potential measurements in renal afferent and efferent arterioles: actions of angiotensin II. Am. J. Physiol. 273 (Renal Physiol. 42): F307-F314, 1997.
52. Loutzenhiser, R., and M. Epstein. Effects of calcium channel antagonists on renal hemodynamics. Am. J. Physiol. 249 (Renal Fluid Electrolyte Physiol. 18): F619-F629, 1985.
53. Loutzenhiser, R., and M. Epstein. The renal hemodynamic effects of calcium antagonists. In: Calcium Antagonists and the Kidney, edited by M. Epstein and R. Loutzenhiser. Philadelphia, PA: Hanley & Belfus, 1990, p. 33-73.
54. Loutzenhiser, R., M. Epstein, and C. Horton. Inhibition by diltiazem of pressure-induced afferent vasoconstriction in the isolated perfused rat kidney. Am. J. Cardiol. 59: 72A-75A, 1987.
55. Loutzenhiser, R., K. Hayashi, and M. Epstein. Divergent effects of KCl-induced depolarization on afferent and efferent arterioles. Am. J. Physiol. 257 (Renal Fluid Electrolyte Physiol. 26): F561-F564, 1989.
56. Maddox, D. A., W. M. Deen, and B. M. Brenner. Glomerular filtration. In: Handbook of Physiology. Renal Physiology. Bethesda, MD: Am. Physiol. Soc., 1992, sect. 8, vol. I, chapt. 13, p. 545-638.
57. Majid, D. S. A., and L. G. Navar. Suppression of blood flow autoregulation plateau during nitric oxide blockade in canine kidney. Am. J. Physiol. 262 (Renal Fluid Electrolyte Physiol. 31): F40-F46, 1992.
58. McGiff, J. C. Cytochrome P-450 metabolism of arachidonic acid. Annu. Rev. Pharmacol. Toxicol. 31: 339-369, 1991.
59. Meininger, G. A., and M. J. Davis. Cellular mechanisms involved in the vascular myogenic response. Am. J. Physiol. 263 (Heart Circ. Physiol. 32): H647-H659, 1992.
60. Mitchell, K. D., and L. G. Navar. Tubuloglomerular feedback responses during peritubular infusions of calcium channel blockers. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F537-F544, 1990.
61. Mitchell, K. D., and L. G. Navar. Modulation of tubuloglomerular feedback responsiveness by extracellular ATP. Am. J. Physiol. 264 (Renal Fluid Electrolyte Physiol. 33): F458-F466, 1993.
62. Mitchell, K. D., and L. G. Navar. Intrarenal actions of angiotensin II in the pathogenesis of experimental hypertension. In: Hypertension: Pathophysiology, Diagnosis, and Management, edited by J. H. Laragh and B. M. Brenner. New York: Raven, 1995, p. 1437-1450.
63. Mundel, P., S. Bachmann, M. Bader, A. Fischer, W. Kummer, B. Mayer, and W. Kriz. Expression of nitric oxide synthase in kidney macula densa cells. Kidney Int. 42: 1017-1019, 1992.
64. Narayanan, J., M. Imig, R. J. Roman, and D. R. Harder. Pressurization of isolated renal arteries increases inositol trisphosphate and diacylglycerol. Am. J. Physiol. 266 (Heart Circ. Physiol. 35): H1840-H1845, 1994.
65. Navar, L. G. Renal autoregulation: perspectives from whole kidney and single nephron studies. Am. J. Physiol. 234 (Renal Fluid Electrolyte Physiol. 3): F357-F370, 1978.
66. Navar, L. G., P. D. Bell, and T. J. Burke. Role of a macula densa feedback mechanism as a mediator of renal autoregulation. Kidney Int. 22, Suppl. 12: S157-S164, 1982.
67. Navar, L. G., W. J. Champion, and C. E. Thomas. Effects of calcium channel blockade on renal vascular resistance responses to changes in perfusion pressure and angiotensin-converting enzyme inhibition in dogs. Circ. Res. 58: 874-881, 1986.
68. Navar, L. G., A. P. Evan, and L. Rosivall. Microcirculation of the kidneys. In: The Physiology and Pharmacology of the Microcirculation, edited by N. Mortillaro. New York: Academic, 1983, p. 397-488.
69. Navar, L. G., E. W. Inscho, D. S. A. Majid, J. D. Imig, L. M. Harrison-Bernard, and K. D. Mitchell. Paracrine regulation of the renal microcirculation. Physiol. Rev. 76: 425-536, 1996.
70. Navar, L. G., L. Lewis, A. Hymel, B. Braam, and K. D. Mitchell. Tubular fluid concentrations and kidney contents of angiotensins I and II in anesthetized rats. J. Am. Soc. Nephrol. 5: 1153-1158, 1994.
71. Nelson, M. T., J. B. Patlak, J. F. Worley, and N. B. Standen. Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone. Am. J. Physiol. 259 (Cell Physiol. 28): C3-C18, 1990.
72. Ohishi, K., P. K. Carmines, E. W. Inscho, and L. G. Navar. EDRF-angiotensin II interactions in rat juxtamedullary afferent and efferent arterioles. Am. J. Physiol. 263 (Renal Fluid Electrolyte Physiol. 32): F900-F906, 1992.
73. Ono, H., H. Kokubun, and K. Hashimoto. Abolition by calcium antagonists of the autoregulation of renal blood flow. Naunyn Schmiedebergs Arch. Pharmacol. 285: 201-207, 1974.
74. Osswald, H. The role of adenosine in the regulation of glomerular filtration rate and renin secretion. Trends Pharmacol. Sci. 5: 94-97, 1984.
75. Rembold, C. M. Regulation of contraction and relaxation in arterial smooth muscle. Hypertension 20: 129-137, 1992.
76. Robertson, C. R., W. M. Deen, J. L. Troy, and B. M. Brenner. Dynamics of glomerular ultrafiltration in the rat. III. Hemodynamics and autoregulation. Am. J. Physiol. 223: 1191-1200, 1972.
77. Roman, R. J., and D. R. Harder. Cellular and ionic signal transduction mechanisms for the mechanical activation of renal arterial vascular smooth muscle. J. Am. Soc. Nephrol. 4: 986-996, 1993.
78. Roman, R. J., and D. R. Harder. Cytochrome P450 metabolites of arachidonic acid in the control of vascular tone. In: Mechanoreception by the Vascular Wall, edited by G. M. Rubanyi. Mount Kisco, NY: Futura, 1993, p. 155-172.
79. Rosivall, L., P. Youngblood, and L. G. Navar. Renal autoregulatory efficiency during angiotensin-converting enzyme inhibition in dogs on a low sodium diet. Renal Physiol. 9: 18-28, 1986.
80. Sanchez-Ferrer, C. F., R. J. Roman, and D. R. Harder. Pressure-dependent contraction of rat juxtamedullary afferent arterioles. Circ. Res. 64: 790-798, 1989.
81. Schnermann, J., and J. Briggs. The juxtaglomerular apparatus. In: The Kidney: Physiology and Pathophysiology, edited by D. W. Seldin and G. Giebisch. New York: Raven, 1992, p. 1249-1289.
82. Schnermann, J., and J. P. Briggs. Restoration of tubuloglomerular feedback in volume-expanded rats by angiotensin II. Am. J. Physiol. 259 (Renal Fluid Electrolyte Physiol. 28): F565-F572, 1990.
83. Schnermann, J., J. P. Briggs, and C. P. Weber. Tubuloglomerular feedback, prostaglandins, and angiotensin in the autoregulation of glomerular filtration rate. Kidney Int. 25: 53-64, 1984.
84. Schnermann, J., and D. Marver. ATPase activity in macula densa cells of the rabbit kidney. Pflügers Arch. 407: 82-86, 1986.
85. 1 receptor blockade. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F553-F561, 1990.
86. 1A receptor-deficient mice. Am. J. Physiol. 273 (Renal Physiol. 42): F315-F320, 1997.
87. Spielman, W. S., and L. J. Arend. Adenosine receptors and signaling in the kidney. Hypertension 17: 117-130, 1991.
88. Steinhausen, M., M. Blum, J. T. Fleming, F. G. Holz, N. Parekh, and D. L. Wiegman. Visualization of renal autoregulation in the split hydronephrotic kidney of rats. Kidney Int. 35: 1151-1160, 1989.
89. Takenaka, T., L. M. Harrison-Bernard, E. W. Inscho, P. K. Carmines, and L. G. Navar. Autoregulation of afferent arteriolar blood flow in juxtamedullary nephrons. Am. J. Physiol. 267 (Renal Fluid Electrolyte Physiol. 36): F879-F887, 1994.
90. Thompson, C. I., and W. S. Spielman. Renal hemodynamic effects of exogenously administered adenosine and polyadenylic acid. Am. J. Physiol. 263 (Renal Fluid Electrolyte Physiol. 32): F816-F823, 1992.
91. Thorup, C., and A. E. G. Persson. Inhibition of locally produced nitric oxide resets tubuloglomerular feedback mechanism. Am. J. Physiol. 267 (Renal Fluid Electrolyte Physiol. 36): F606-F611, 1994.
92. Thurau, K. Nature of autoregulation of renal blood flow. In: Proceedings of the Third International Congress of Nephrology, edited by G. E. Schreiner. New York: Karger, 1966, p. 162-173.
93. Tojo, A., S. S. Gross, L. Zhang, C. C. Tisher, H. H. H. W. Schmidt, C. S. Wilcox, and K. M. Madsen. Immunocytochemical localization of distinct isoforms of nitric oxide synthase in the juxtaglomerular apparatus of normal rat kidney. J. Am. Soc. Nephrol. 4: 1438-1447, 1994.
94. Welch, W. J., and C. S. Wilcox. Modulating role for thromboxane in the tubuloglomerular feedback response in the rat. J. Clin. Invest. 81: 1843-1849, 1988.
95. Welch, W. J., and C. S. Wilcox. Feedback responses during sequential inhibition of angiotensin and thromboxane. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F457-F466, 1990.
96. Welch, W. J., and C. S. Wilcox. Potentiation of tubuloglomerular feedback in the rat by thromboxane mimetic: role of macula densa. J. Clin. Invest. 89: 1857-1865, 1992.
97. Wilcox, C. S., and W. J. Welch. TGF and nitric oxide: effects of salt intake and salt-sensitive hypertension. Kidney Int. 49, Suppl. 55: S9-S13, 1996.
98. Wilcox, C. S., W. J. Welch, F. Murad, S. S. Gross, G. Taylor, R. Levi, and H. H. H. W. Schmidt. Nitric oxide synthase in macula densa regulates glomerular capillary pressure. Proc. Natl. Acad. Sci. USA 89: 11993-11997, 1992.
99. Wright, F. S., and J. Schnermann. Interference with feedback control of glomerular filtration by furosemide, triflocin and cyanide. J. Clin. Invest. 53: 1695-1708, 1974.
100. Yared, A., and T. Yoshioka. Autoregulation of glomerular filtration in the young. Semin. Nephrol. 9: 94-97, 1989.
101. Zou, A.-P., J. D. Imig, P. R. Ortiz De Montellano, Z. Sui, J. R. Falck, and R. J. Roman. Effect of P-450 ω-hydroxylase metabolites of arachidonic acid on tubuloglomerular feedback. Am. J. Physiol. 266 (Renal Fluid Electrolyte Physiol. 35): F934-F941, 1994.