Functional repair of a mutant chloride channel using a trans-splicing ribozyme

Journal of Clinical Investigation

Volumn 110, Issue 12, 2002, Pages 1783-1789

  Rogers, Christopher S ^a   Vanoye, Carlos G ^a   Sullenger, Bruce A ^b   George Jr , Alfred L ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIDE CHANNEL; MEMBRANE PROTEIN; MESSENGER RNA; MUTANT PROTEIN; RIBOZYME;

ARTICLE; CONTROLLED STUDY; GENE MUTATION; GENE TARGETING; GENE THERAPY; HUMAN; HUMAN CELL; INTRON; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; RNA TRANSCRIPTION; SKELETAL MUSCLE; TETRAHYMENA; THOMSEN DISEASE; TRANS SPLICING; WILD TYPE;

ANIMALS; BASE SEQUENCE; CELL LINE; CHLORIDE CHANNELS; DOGS; EXONS; HUMANS; MOLECULAR SEQUENCE DATA; MUSCLE, SKELETAL; MUTATION; MYOTONIA CONGENITA; PATCH-CLAMP TECHNIQUES; PROTOZOAN PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, CATALYTIC; RNA, MESSENGER; TETRAHYMENA; TRANS-SPLICING;

EID: 0036951195     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200216481     Document Type: Article

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