메뉴 건너뛰기




Volumn 8, Issue 6 SUPPL., 2002, Pages

Gene transfer of β-adrenergic signaling components for heart failure

Author keywords

Adrenergic receptors; Desensitization; G protein coupled receptor kinase; Gene therapy; Heart failure; Transgenic mice

Indexed keywords

BETA ADRENERGIC RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; REGULATOR PROTEIN;

EID: 0036947237     PISSN: 10719164     EISSN: None     Source Type: Journal    
DOI: 10.1054/jcaf.2002.129287     Document Type: Conference Paper
Times cited : (4)

References (32)
  • 1
    • 0000371958 scopus 로고
    • Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure
    • Leimbach WN, Wallin G, Victor RG, Aylward PE, Sundlof G, Mark AL: Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure. Circulation 1986;93:720-729
    • (1986) Circulation , vol.93 , pp. 720-729
    • Leimbach, W.N.1    Wallin, G.2    Victor, R.G.3    Aylward, P.E.4    Sundlof, G.5    Mark, A.L.6
  • 2
    • 0024154085 scopus 로고
    • Regulation of cardiac ion channels by catecholamines, acetylcholine and second messeanger systems
    • Hartzell HC: Regulation of cardiac ion channels by catecholamines, acetylcholine and second messeanger systems. Prog Biophys Mol Biol 1988;53:165-257
    • (1988) Prog Biophys Mol Biol , vol.53 , pp. 165-257
    • Hartzell, H.C.1
  • 3
    • 0027819354 scopus 로고
    • β-adrenoreceptors in cardiac disease
    • Brodde OE: β-adrenoreceptors in cardiac disease. Pharmac Ther 1993;60:405-430
    • (1993) Pharmac Ther , vol.60 , pp. 405-430
    • Brodde, O.E.1
  • 4
    • 0027368165 scopus 로고
    • Structure and mechanism of the G protein-coupled receptor kinases
    • Inglese J, Freedman NJ, Koch WJ, Lefkowitz RJ: Structure and mechanism of the G protein-coupled receptor kinases. J Biol Chem 1993;268:23723-23738
    • (1993) J Biol Chem , vol.268 , pp. 23723-23738
    • Inglese, J.1    Freedman, N.J.2    Koch, W.J.3    Lefkowitz, R.J.4
  • 5
    • 0033982570 scopus 로고    scopus 로고
    • Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart
    • Eckhart AD, Duncan SJ, Penn RB, Benovic JL, Lefkowitz RJ, Koch WJ: Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart. Circ Res 2000;86:43-50
    • (2000) Circ Res , vol.86 , pp. 43-50
    • Eckhart, A.D.1    Duncan, S.J.2    Penn, R.B.3    Benovic, J.L.4    Lefkowitz, R.J.5    Koch, W.J.6
  • 6
    • 0025352299 scopus 로고
    • β-arrestin: A protein that regulates β-adrenergic receptor function
    • Lohse MJ, Benovic JL, Codina J, Caron MG, Lefkowitz RJ: β-arrestin: A protein that regulates β-adrenergic receptor function. Science 1990;248:1547-1550
    • (1990) Science , vol.248 , pp. 1547-1550
    • Lohse, M.J.1    Benovic, J.L.2    Codina, J.3    Caron, M.G.4    Lefkowitz, R.J.5
  • 7
    • 0027481032 scopus 로고
    • The binding site for the βγ subunits of heterotrimeric G proteins on the β-adrenergic receptor kinase
    • Koch WJ, Inglese J, Stone WC, Lefkowitz R: The binding site for the βγ subunits of heterotrimeric G proteins on the β-adrenergic receptor kinase. J Biol Chem 1993;268:8256-8260
    • (1993) J Biol Chem , vol.268 , pp. 8256-8260
    • Koch, W.J.1    Inglese, J.2    Stone, W.C.3    Lefkowitz, R.4
  • 9
    • 0028670476 scopus 로고
    • Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by Gβγ activation of p21ras
    • Koch WJ, Hawes BE, Allen LF, Lefkowitz RJ: Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by Gβγ activation of p21ras. Proc Natl Acad Sci USA 1994;91:12706-12710
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12706-12710
    • Koch, W.J.1    Hawes, B.E.2    Allen, L.F.3    Lefkowitz, R.J.4
  • 10
    • 0028085776 scopus 로고
    • Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates Gβγ-mediated signaling
    • Koch WJ, Hawes BE, Inglese J, Luttrell LM, Lefkowitz RJ: Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates Gβγ-mediated signaling. J Biol Chem 1994;269:6193-6197
    • (1994) J Biol Chem , vol.269 , pp. 6193-6197
    • Koch, W.J.1    Hawes, B.E.2    Inglese, J.3    Luttrell, L.M.4    Lefkowitz, R.J.5
  • 12
    • 0027497584 scopus 로고
    • Altered expression of β-adrenergic receptor kinase and β-1-adrenergic receptors in the failing human heart
    • Ungerer M, Bohm M, Elce JS, Erdmann E, Lohse MJ: Altered expression of β-adrenergic receptor kinase and β-1-adrenergic receptors in the failing human heart. Circulation 1993;87:454-463
    • (1993) Circulation , vol.87 , pp. 454-463
    • Ungerer, M.1    Bohm, M.2    Elce, J.S.3    Erdmann, E.4    Lohse, M.J.5
  • 13
    • 3042917919 scopus 로고
    • Modulation of adrenergic receptors and G-transduction proteins in failing human ventricular myocardium
    • Feldman AM: Modulation of adrenergic receptors and G-transduction proteins in failing human ventricular myocardium. Circulation 1993;87:IV27-IV34
    • (1993) Circulation , vol.87
    • Feldman, A.M.1
  • 15
    • 0027360573 scopus 로고
    • The development of positive inotropic agents for chronic heart failure: How have we gone astray?
    • Packer M: The development of positive inotropic agents for chronic heart failure: How have we gone astray? J Am Coll Cardiol 1993;22:119A-126A
    • (1993) J Am Coll Cardiol , vol.22
    • Packer, M.1
  • 16
    • 0034636080 scopus 로고    scopus 로고
    • Catecholamines, cardiac "β"-adrenergic receptors, and heart failure
    • Lefkowitz RJ, Rockman HA, Koch WJ: Catecholamines, cardiac "β"-adrenergic receptors, and heart failure. Circulation 2000;101:1634-1637
    • (2000) Circulation , vol.101 , pp. 1634-1637
    • Lefkowitz, R.J.1    Rockman, H.A.2    Koch, W.J.3
  • 18
    • 0033535942 scopus 로고    scopus 로고
    • Progressive hypertrophy and heart failure in β-1 adrenergic receptor transgenic mice
    • Engelhardt S, Hein L, Wiesmann F, Lohse MJ: Progressive hypertrophy and heart failure in β-1 adrenergic receptor transgenic mice. Proc Natl Acad Sci USA 1999;96:7059-7064
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7059-7064
    • Engelhardt, S.1    Hein, L.2    Wiesmann, F.3    Lohse, M.J.4
  • 19
    • 0034636061 scopus 로고    scopus 로고
    • Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: Critical role for expression level
    • Liggett SB, Tepe NM, Lorenz JN, Canning AM, Jantz TD, Mitarai S, Yatani A, Dorn GW: Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: Critical role for expression level. Circulation 2000;101:1634-1637
    • (2000) Circulation , vol.101 , pp. 1634-1637
    • Liggett, S.B.1    Tepe, N.M.2    Lorenz, J.N.3    Canning, A.M.4    Jantz, T.D.5    Mitarai, S.6    Yatani, A.7    Dorn, G.W.8
  • 20
    • 0032729995 scopus 로고    scopus 로고
    • Opposing effects of β1- and β2-adrenergic receptors on cardiac myocyte apoptosis: Role of a pertussis toxin-sensitive G protein
    • Communal C, Singh K, Sawyer DB, Colucci WS: Opposing effects of β1- and β2-adrenergic receptors on cardiac myocyte apoptosis: Role of a pertussis toxin-sensitive G protein. Circulation 1999;100:2210-2212
    • (1999) Circulation , vol.100 , pp. 2210-2212
    • Communal, C.1    Singh, K.2    Sawyer, D.B.3    Colucci, W.S.4
  • 21
    • 0032573192 scopus 로고    scopus 로고
    • Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by β-adrenergic receptor stimulation and blockade
    • Iaccarino G, Tomhave ED, Lefkowitz RJ, Koch WJ: Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by β-adrenergic receptor stimulation and blockade. Circulation 1998;98:1783-1789
    • (1998) Circulation , vol.98 , pp. 1783-1789
    • Iaccarino, G.1    Tomhave, E.D.2    Lefkowitz, R.J.3    Koch, W.J.4
  • 23
    • 0030933063 scopus 로고    scopus 로고
    • MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure
    • Arber S, Hunter JJ, Ross J Jr, Hongo M, Sansig G, Borg J, Perriad JC, Chien KR, Caroni P: MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure. Cell 1997;88:393-403
    • (1997) Cell , vol.88 , pp. 393-403
    • Arber, S.1    Hunter, J.J.2    Ross J., Jr.3    Hongo, M.4    Sansig, G.5    Borg, J.6    Perriad, J.C.7    Chien, K.R.8    Caroni, P.9
  • 26
    • 0035826710 scopus 로고    scopus 로고
    • Cardiac βARK1 inhibition prolongs survival and augments β blocker therapy in a mouse model of severe heart failure
    • Harding V, Jones L, Lefkowitz RJ, Koch WJ, Rockman HA: Cardiac βARK1 inhibition prolongs survival and augments β blocker therapy in a mouse model of severe heart failure. Proc Natl Acad Sci USA 2001;98:5809-5814
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5809-5814
    • Harding, V.1    Jones, L.2    Lefkowitz, R.J.3    Koch, W.J.4    Rockman, H.A.5
  • 28
    • 0031018004 scopus 로고    scopus 로고
    • Potentiation of β-adrenergic signaling by adenoviral-mediated gene transfer in adult rabbit ventricular myocytes
    • Drazner MH, Peppel KC, Dyer S, Grant AO, Koch WJ, Lefkowitz RJ: Potentiation of β-adrenergic signaling by adenoviral-mediated gene transfer in adult rabbit ventricular myocytes. J Clin Invest 1996;99:288-296
    • (1996) J Clin Invest , vol.99 , pp. 288-296
    • Drazner, M.H.1    Peppel, K.C.2    Dyer, S.3    Grant, A.O.4    Koch, W.J.5    Lefkowitz, R.J.6
  • 30
    • 0034625008 scopus 로고    scopus 로고
    • Preservation of myocardial β-adrenergic receptor signaling delays the development of heart failure after myocardial infarction
    • White DC, Hata JA, Shah AS, Glower DD, Lefkowitz RJ, Koch WJ: Preservation of myocardial β-adrenergic receptor signaling delays the development of heart failure after myocardial infarction. Proc Natl Acad Sci USA 2000;97:5428-5433
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5428-5433
    • White, D.C.1    Hata, J.A.2    Shah, A.S.3    Glower, D.D.4    Lefkowitz, R.J.5    Koch, W.J.6
  • 31
    • 17344389993 scopus 로고    scopus 로고
    • Intracoronary adenovirus-mediated delivery and overexpression of the β2-adrenergic receptor in the heart: Prospects for molecular ventricular assistance
    • Shah AS, Lilly RE, Kypson AP, Tai O, Hata JA, Pippen A, Silvestry SC, Lefkowitz RJ, Glower DD, Koch WJ: Intracoronary adenovirus-mediated delivery and overexpression of the β2-adrenergic receptor in the heart: Prospects for molecular ventricular assistance. Circulation 2000;101:408-414
    • (2000) Circulation , vol.101 , pp. 408-414
    • Shah, A.S.1    Lilly, R.E.2    Kypson, A.P.3    Tai, O.4    Hata, J.A.5    Pippen, A.6    Silvestry, S.C.7    Lefkowitz, R.J.8    Glower, D.D.9    Koch, W.J.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.