Neuroanatomical substrates involved in the anxiogenic-like effect of acute fluoxetine treatment

Neuropharmacology

Volumn 43, Issue 8, 2002, Pages 1238-1248

  Salchner, Peter ^a   Singewald, Nicolas ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Anxiety; C fos; Locus coeruleus noradrenaline; Panic; Social interaction test; SSRI

Indexed keywords

FLUOXETINE; NORADRENALIN; PROTEIN FOS;

AMYGDALOID NUCLEUS; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; BRAIN REGION; CELL ACTIVATION; CONTROLLED STUDY; DISEASE EXACERBATION; DOSE RESPONSE; EMOTIONAL STRESS; ESCAPE BEHAVIOR; FEAR; HYPOTHALAMUS; IMMOBILIZATION STRESS; LOCUS CERULEUS; MALE; NERVE PROJECTION; NEUROANATOMY; NONHUMAN; NORADRENALIN RELEASE; NORADRENERGIC NERVE; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 0036945857     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(02)00329-5     Document Type: Article

References (76)

1. Amsterdam J.D., Hornig-Rohan M., Maislin G. Efficacy of alprazolam in reducing fluoxetine-induced jitteriness in patients with major depression. Journal of Clinical Psychiatry. 55:1994;394-400.
2. Artaiz I., Zazpe A., Del Río J. Characterization of serotonergic mechanisms involved in the behavioural inhibition induced by 5-hydroxytryptophan in a modified light-dark test in mice. Behavioural Pharmacology. 9:1998;103-112.
3. Aston-Jones G., Shipley M.T., Chouvet G., Ennis M., van Bockstaele E., Pieribone V., Shiekhattar R., Akaoka H., Drolet G., Astier B., Charléty P., Valentino R.J., Williams J.T. Afferent regulation of locus coeruleus neurons: anatomy, physiology and pharmacology. Barnes C.D., Pompeiano O. Progress in Brain Research. 1991;Elsevier, Amsterdam.
4. Aston-Jones G., Rajkowski J., Cohen J. Role of locus coeruleus in attention and behavioral flexibility. Biological Psychiatry. 46:1999;1309-1320.
5. 1A receptor antagonist WAY-100635. International Journal of Neuropsychopharmacology. 4:2001;399-408.
6. Barnes, C.D., Pompeiano, O., 1991. In: Pompeiano, O. (Eds.), Neurobiology of the Locus Coeruleus. Elsevier, Amsterdam.
7. Beck C.H.M. Acute treatment with antidepressant drugs selectively increases the expression of c-fos in the rat brain. Journal of Psychiatry and Neuroscience. 20:1995;25-32.
8. Beck C.H.M., Fibiger H.C. Conditioned fear-induced changes in behavior and in the expression of the immediate early gene c-fos: with and without diazepam pretreatment. Journal of Neuroscience. 15:1995;709-720.
9. Berridge C.W., Abercrombie E.D. Relationship between locus coeruleus discharge rates and rates of norepinephrine release within neocortex as assessed by in vivo microdialysis. Neuroscience. 93:1999;1263-1270.
10. Bremner J.D., Krystal J.H., Southwick S.M., Charney D.S. Noradrenergic mechanisms in stress and anxiety: I. Preclinical studies. Synapse. 23:1996;28-38.
11. 1A receptor antagonist, WAY 100,635, in the rat. Neuropharmacology. 39:2000;1222-1236.
12. Buda M., Lachuer J., Devauges V., Barbagli B., Blizard D., Sara S.J. Central noradrenergic reactivity to stress in Maudsley rat strains. Neuroscience Letters. 167:1994;33-36.
13. Butler P.D., Weiss J.M., Stout J.C., Nemeroff C.B. Corticotropin-releasing factor produces fear-enhancing and behavioural activating effects following infusion into the locus coeruleus. Journal of Neuroscience. 10:1990;176-183.
14. Campeau S., Falls W.A., Cullinan W.E., Helmreich D.L., Davis M., Watson S.J. Elicitation and reduction of fear: behavioural and neuroendocrine indices and brain induction of the immediate-early gene c-fos. Neuroscience. 78:1997;1087-1104.
15. Catalano G., Hakala S.M., Catalano M.C. Sertraline-induced panic attacks. Clinical Neuropharmacology. 23:2000;164-168.
16. Charney D.S., Bremner J.D., Redmond D.E. Jr. Noradrenergic neural substrates for anxiety and fear. Clinical associations based on preclinical research. Bloom F.E., Kupfer D.J. Psychopharmacology: the Fourth Generation of Progress. 1995;387-395 Raven Press, New York.
17. Charney D.S., Grillon C., Bremner J.D. The neurobiological basis of anxiety and fear: circuits, mechanisms, and neurochemical interactions (part I). Neuroscientist. 4:1998;35-44.
18. Den Boer J.A., Westenberg H.G.M. Involvement of serotonin receptor subtypes in panic disorder: a critical appraisal of the evidence. Westenberg H.G.M., Den Boer J.A., Murphy D.L.M. Advances in the Neurobiology of Anxiety Disorders. 1996;139-172 Wiley, Chichester.
19. 2C receptors. Neuropharmacology. 39:2000;1114-1117.
20. Duncan G.E., Knapp D.J., Breese G.R. Neuroanatomical characterization of Fos induction in rat behavioral models of anxiety. Brain Research. 713:1996;79-91.
21. 1A receptor function. Pharmacology, Biochemistry and Behavior. 62:1999;695-701.
22. Florin-Lechner S.M., Druhan J.P., Aston-Jones G., Valentino R.J. Enhanced norepinephrine release in prefrontal cortex with burst stimulation of the locus coeruleus. Brain Research. 742:1996;89-97.
23. Fuller R.W. Uptake inhibitors increase extracellular serotonin concentration measured by brain microdialysis. Life Sciences. 55:1994;163-167.
24. Gorman J.M. The use of newer antidepressants for panic disorder. Journal of Clinical Psychiatry. 58:(Suppl. 14):1997;54-58.
25. Grant M.M., Weiss J.M. Effects of chronic antidepressant drug administration and electroconvulsive shock on locus coeruleus electrophysiologic activity. Biological Psychiatry. 49:2001;117-129.
26. Griebel G., Moreau J.-L., Jenck F., Misslin R., Martin J.R. Acute and chronic treatment with 5-HT reuptake inhibitors differentially modulate emotional responses in anxiety models in rodents. Psychopharmacology. 113:1994;463-470.
27. Griebel G., Blanchard D.C., Agnes R.S., Blanchard R.J. Differential modulation of antipredator defensive behavior in Swiss-Webster mice following acute or chronic administration of imipramine and fluoxetine. Psychopharmacology. 120:1995;57-66.
28. Griebel G., Blanchard D.C., Blanchard R.J. Predator-elicited flight responses in Swiss-Webster mice: an experimental model of panic attacks. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 20:1996;185-205.
29. Handley S.L. 5-Hydroxytryptamine pathways in anxiety and its treatment. Pharmacology and Therapeutics. 66:1995;103-148.
30. Handley S.L., McBlane J.W. 5HT drugs in animal models of anxiety. Psychopharmacology. 112:1993;13-20.
31. Harro J., Oreland L. Depression as a spreading adjustment disorder of monoaminergic neurons: a case for primary implication of the locus coeruleus. Brain Research Reviews. 38:2001;79-128.
32. Hervás I., Artigas F. Effect of fluoxetine on extracellular 5-hydroxytryptamine in rat brain. Role of 5-HT autoreceptors. European Journal of Pharmacology. 358:1998;9-18.
33. Hoffman G.E., Smith M.S., Verbalis J.G. c-fos and related immediate early gene products as markers of activity in neuroendocrine systems. Frontiers in Neuroendocrinology. 14:1993;173-213.
34. Iwamoto G.A., Wappel S.M., Fox G.M., Buetow K.A., Waldrop T.G. Identification of diencephalic and brainstem cardiorespiratory areas activated during exercise. Brain Research. 726:1996;109-122.
35. Kawahara Y., Kawahara H., Westerink B.H.C. Tonic regulation of the activity of noradrenergic neurons in the locus coeruleus of the conscious rat studied by dual-probe microdialysis. Brain Research. 823:1999;42-48.
36. Kent J.M., Coplan J.D., Gorman J.M. Clinical utility of the selective serotonin reuptake inhibitors in the spectrum of anxiety. Biological Psychiatry. 44:1998;812-824.
37. Knapp D.J., Duncan G.E., Crews F.T., Breese G.R. Induction of Fos-like proteins and ultrasonic vocalizations during ethanol withdrawal: further evidence for withdrawal-induced anxiety. Alcoholism, Clinical and Experimental Research. 22:1998;481-493.
38. Koks S., Beljajev S., Koovit I., Abramov U., Bourin M., Vasar E. 8-OH-DPAT, but not deramciclane, antagonizes the anxiogenic-like action of paroxetine in an elevated plus-maze. Psychopharmacology. 153:2001;365-372.
39. Kovács K.J. c-Fos as a transcription factor: a stressful (re)view from a functional map. Neurochemistry International. 33:1998;287-297.
40. Libet B., Gleason C.A. The human locus coeruleus and anxiogenesis. Brain Research. 634:1994;178-180.
41. Lightowler S., Kennett G.A., Williamson I.J., Blackburn T.P., Tulloch I.F. Anxiolytic-like effect of paroxetine in a rat social interaction test. Pharmacology, Biochemistry and Behavior. 49:1994;281-285.
42. Lino-de-Oliveira C., Sales A.J., Del Bel E.A., Silveira M.C.L., Guimaraes F.S. Effects of acute and chronic fluoxetine treatments on restraint stress-induced Fos expression. Brain Research Bulletin. 55:2001;747-754.
43. Lipinski J.F. Jr., Mallya G., Zimmerman P., Pope H.G. Jr. Fluoxetine-induced akathasia: clinical and theoretical implications. Journal of Clinical Psychiatry. 50:1989;339-342.
44. McQuade R., Stanford S.C. Differences in central noradrenergic and behavioural responses of Maudsley non-reactive and Maudsley reactive inbred rats on exposure to an aversive novel environment. Journal of Neurochemistry. 76:2001;21-28.
45. Morgan J.I., Curran T. Stimulus-transcription coupling in neurons: role of cellular immediate-early genes. Trends in Neuroscience. 12:1989;459-462.
46. Page M.E., Abercrombie E.D. An analysis of the effects of acute and chronic fluoxetine on extracellular norepinephrine in the rat hippocampus during stress. Neuropsychopharmacology. 16:1997;419-425.
47. Palmer A.A., Printz M.P. Airpuff startle stress elicited fos expression in brain cardiovascular areas of young SHR and WKY rats. Clinical and Experimental Hypertension. 21:1999;1061-1081.
48. Palmer A.A., Printz M.P. Strain differences in fos expression following airpuff startle in spontaneously hypertensive and Wistar Kyoto rats. Neuroscience. 89:1999;965-978.
49. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates. 1998;Academic Press, Sydney.
50. Philippu A., Prast H., Singewald N. Identification and dynamics of neuronal modulation and function in brain structures and nuclei by continuous determination of transmitter release rates using the push-pull superfusion technique: a compelling approach to in vivo brain research. Scientia Pharmaceutica. 64:1996;609-618.
51. A-receptors in rodents. Functional Neurology. 6:1991;393-403.
52. Rasmussen K., Jacobs B.L. Single unit activity of locus coeruleus neurons in the freely moving cat. II. Conditioning and pharmacologic studies. Brain Research. 371:1986;335-344.
53. Redmond D.E. Jr. Studies of the nucleus locus coeruleus in monkeys and hypothesis for neuropsychopharmacology. Meltzer H.Y. Psychopharmacology: The Third Generation of Progress. 1987;967-975 Raven Press, New York.
54. Sanchéz C., Meier E. Behavioral profiles of SSRIs in animal models of depression, anxiety and aggression. Are they all alike? Psychopharmacology. 129:1997;197-205.
55. Salchner P., Singewald N. Effects of fluoxetine on emotional stress-induced c-Fos expression and noradrenaline release in the rat locus coeruleus. European Journal of Neuroscience. 12:(Suppl. 11):2000;52.
56. Segal M. Serotonergic innervation of the locus coeruleus from the dorsal raphe and its action on responses to noxious stimuli. Journal of Physiology. 286:1979;401-415.
57. Senba E., Ueyama T. Stress-induced expression of immediate early genes in the brain and peripheral organs of the rat. Neuroscience Research. 29:1997;183-207.
58. Sills T.L., Greenshaw A.J., Baker G.B., Fletcher P.J. Acute fluoxetine treatment potentiates amphetamine hyperactivity and amphetamine-induced nucleus accumbens dopamine release: possible pharmacokinetic interaction. Psychopharmacology. 141:1999;421-427.
59. Silva R.C.B., Brandao M.L. Acute and chronic effects of gepirone and fluoxetine in rats tested in the elevated plus-maze: an ethological analysis. Pharmacology Biochemistry and Behavior. 65:2000;209-216.
60. Silva M.T., Alves C.R., Santarem E.M. Anxiogenic-like effect of acute and chronic fluoxetine on rats tested on the elevated plus-maze. Brazilian Journal of Medical and Biological Research. 32:1999;333-339.
61. Silveira M.C.L., Sandner G., Graeff F.G. Induction of Fos immunoreactivity in the brain by exposure to the elevated plus-maze. Behavioural Brain Research. 56:1993;115-118.
62. Singewald N., Philippu A. Catecholamine release in the locus coeruleus is modified by experimentally induced changes in haemodynamics. Naunyn-Schmiedeberg's Archives of Pharmacology. 347:1993;21-27.
63. Singewald N., Philippu A. Release of neurotransmitters in the locus coeruleus. Progress in Neurobiology. 56:1998;237-267.
64. Singewald N., Sharp T. Neuroanatomical targets of panicogenic drugs in the hindbrain as revealed by Fos immunocytochemistry. Neuroscience. 98:2000;759-770.
65. Singewald N., Zhou G.-Y., Schneider C. Release of excitatory and inhibitory amino acids from the locus coeruleus of conscious rats by cardiovascular stimuli and various forms of acute stress. Brain Research. 704:1995;42-50.
66. Singewald N., Kaehler S., Philippu A. Noradrenaline release in the locus coeruleus of conscious rats is triggered by drugs, stress and blood pressure changes. NeuroReport. 10:1999;1583-1587.
67. Stanford S.C. Central noradrenergic neurones and stress. Pharmacology and Therapeutics. 68:1995;297-342.
68. Sullivan G.M., Coplan J.D., Kent J.M., Gorman J.M. The noradrenergic system in pathological anxiety: a focus on panic with relevance to generalized anxiety and phobias. Biological Psychiatry. 46:1999;1205-1218.
69. Szabo S.T., de Montigny C., Blier P. Modulation of noradrenergic neuronal firing by selective serotonin reuptake blockers. British Journal of Pharmacology. 126:1999;568-571.
70. Tanaka M., Yoshida M., Emoto H., Ishii H. Noradrenaline systems in the hypothalamus, amygdala and locus coeruleus are involved in the provocation of anxiety: basic studies. European Journal of Pharmacology. 405:2000;397-406.
71. To C.T., Bagdy G. Anxiogenic effect of central CCK administration is attenuated by chronic fluoxetine or ipsapirone treatment. Neuropharmacology. 38:1999;279-282.
72. To C.T., Anheuer Z.E., Bagdy G. Effects of acute and chronic fluoxetine treatment on CRH-induced anxiety. NeuroReport. 10:1999;553-555.
73. Torres G., Horowitz J.M., Laflamme N., Rivest S. Fluoxetine induces the transcription of genes encoding c-fos, corticotropin-releasing factor and its type 1 receptor in rat brain. Neuroscience. 87:1998;463-477.
74. Van Bockstaele E.J., Bajic D., Proudfit H., Valentino R.J. Topographic architecture of stress-related pathways targeting the noradrenergic locus coeruleus. Physiology and Behavior. 73:2001;273-283.
75. Vissing J., Andersen M., Diemer N.H. Exercise-induced changes in local cerebral glucose utilization in the rat. Journal of Cerebral Blood Flow and Metabolism. 16:1996;729-736.
76. Weiss J.M., Stout J.C., Aaron M.F., Quan N., Owens M.J., Butler P.D., Nemeroff C.B. Depression and anxiety: role of the locus coeruleus and corticotropin-releasing factor. Brain Research Bulletin. 35:1994;561-572.