Prediction of food protein allergenicity: A bio-informatic learning systems approach

In Silico Biology

Volumn 2, Issue 4, 2002, Pages 525-534

  Zorzet, Anna ^a   Gustafsson, Mats ^b   Hammerling, Ulf ^a  

^a NATIONAL FOOD ADMINISTRATION   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Computational toxicology; Food allergy; Risk assessment

Indexed keywords

AMINO ACID; FOOD ALLERGEN; PROTEIN;

ALGORITHM; ALLERGENICITY; AMINO ACID SEQUENCE; ARTICLE; BIOINFORMATICS; CLASSIFICATION; COMPUTER ANALYSIS; DATA BASE; DIGESTION; FOOD ALLERGY; FOOD ANALYSIS; FOOD SAFETY; IMMUNOASSAY; METHODOLOGY; PREDICTION; RISK ASSESSMENT; STANDARD; VALIDATION PROCESS;

ALGORITHMS; ALLERGENS; AMINO ACIDS; COMPUTATIONAL BIOLOGY; DATABASES; FOOD HYPERSENSITIVITY; HUMANS; RISK ASSESSMENT; SOFTWARE;

EID: 0036941115     PISSN: 13866338     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Aalberse, R. C. (2000). Structural biology of allergens. J. Allergy Clin. Immunol. 106, 228-238.
2. Allergen nomenclature. http://www.allergen.org; 2001-10-11.
3. Astwood, J. D., Leach, J. N. and Fuchs, R. L. (1996) Stability of food allergens to digestion in vitro. Nat. Biotechnol. 14, 1269-1273.
4. Bairoch, A. and Apweiler, R. (2000). The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000. Nucleic Acids Res. 28, 45-48.
5. Baldi, P. and Brunak, S. (2001). Bioinformatics: The Machine Learning Approach. MIT Press.
6. Breiteneder, H. and Ebner, C. (2000). Molecular and biochemical classification of plant-derived food allergens. J. Allergy Clin. Immunol. 106, 27-36.
7. Bruijnzeel-Koomen, C., Ortolani, C., Aas, K., Bindslev-Jensen, C., Bjorksten, B., Moneret-Vautrin, D. and Wuthrich, B. (1995). Adverse reactions to food. European Academy of Allergology and Clinical Immunology Subcommittee. Allergy 50, 623-635.
8. ExPASy Molecular Biology Server of the Swiss Institute of Bioinformatics. http://www.expasy.org; 2001-10-11.
9. FAO. (1995). Report of the FAO Technical Consultation on Food Allergies. Food and Agriculture Organization of the United Nations, Rome.
10. FAO. (2001). Evaluation of allergenicity of genetically modified foods. Joint FAO/WHO Expert Consultation on Allergenicity of Foods Derived from Biotechnology. Food and Agricultural Organization of the United Nations (FAO), Rome, Italy.
11. Farrp Allergen Database. http://www.allergenonline.com; 2001-10-11.
12. Fuchs, R. L. and Astwood, J. D. (1996). Allergenicity assessment of foods derived from genetically modified plants. Food Technol. 50, 83-88.
13. Gendel, S. M. (1998). The use of amino acid sequence alignments to assess potential allergenicity of proteins used in genetically modified foods. Adv. Food Nutr. Res. 42, 45-62.
14. Hastie, T., Tibshirani, R. and Friedman, J. (2001). The Elements of Statistical Learning: Data Mining, Inference and Prediction. Springer-Verlag, New York.
15. Hefle, S.L., Nordlee, J. A. and Taylor, S. L. (1996). Allergenic foods. Crit. Rev. Food Sci. Nutr. 36 Suppl., S69-S89.
16. Hileman, R. E., Silvanovich, A., Goodman, R. E., Rice, E. A., Holleschak, G., Astwood, J. D. and Hefle, S. L. (2002). Bioinformatic methods for allergenicity assessment using a comprehensive allergen database. Int. Arch. Allergy Immunol. 128, 280-291.
17. IFT, (2000). IFT Expert Report in Biotechnology and Foods: Introduction. Food Technol. 54, 124-136.
18. Melo, V. M. M., Xavier-Filho, J., Lima, M. S. and Prouvost-Dannon, A. (1994). Allergenicity and tolerance to proteins from Brazil nut (Bertholletia excelsa H. B. K.). Food Agric. Immunol. 6, 185-195.
19. Metcalfe, D. D., Astwood, J. D., Townsend, R., Sampson, H. A., Taylor, S. L. and Fuchs, R. L. (1996). Assessment of the allergenic potential of foods derived from genetically engineered crop plants. Crit. Rev. Food Sci. Nutr. 36 Suppl., S165-S186.
20. Moneret-Vautrin, D. A. and Kanny, G. (1995). [Food-induced anaphylaxis. A new French multicenter study]. Bull. Acad. Natl. Med. 179, 161-172, 178-184; discussion 173-167.
21. Nordlee, J. A., Taylor, S. L., Townsend, J. A., Thomas, L. A. and Bush, R. K. (1996). Identification of a Brazil-nut allergen in transgenic soybeans. N. Engl. J. Med. 334, 688-692.
22. Pearson, W. R. (1995). Comparison of methods for searching protein sequence databases. Protein Sci. 4, 1145-1160.
23. Pearson, W. R. (2000). Flexible sequence similarity searching with the FASTA3 program package. Methods Mol. Biol. 132, 185-219.
24. Pearson, W. R. and Lipman, D. J. (1988). Improved tools for biological sequence comparison. Proc. Natl. Acad. Sci. USA 85, 2444-2448.
25. Sampson, H. A. (1999). Food allergy. Part 1: Immunopathogenesis and clinical disorders. J. Allergy Clin. Immunol. 103, 717-728.
26. Sampson, H. A. (2000). Food anaphylaxis. Br. Med. Bull. 56, 925-935.
27. Sandberg, M., Eriksson, L., Jonsson, J., Sjostrom, M. and Wold, S. (1998). New chemical descriptors relevant for the design of biologically active peptides. A multivariate characterization of 87 amino acids. J. Med. Chem. 41, 2481-2491.
28. Stone, M. (1974). Cross-validatory choice and assessment of statistical predictions. J. Royal Statistical Society 36, 111-147.
29. Taylor, S. L. (1997). Assessment of the allergenicity of genetically modified foods. Agbiotech News Information 9, 229N-234N.
30. Taylor, S. L. (2002). Protein allergenicity assessment of foods produced through agricultural biotechnology. Annu. Rev. Pharmacol. Toxicol. 42, 99-112.
31. The Allergen Database. http://www.csl.gov.uk/allergen; 2001-10-11.
32. The Allergen Sequence Database. http://www.iit.edu/~sgendel/foodallr.htm; 2001-10-11.
33. The Protall Database. http://www.ifr.bbsrc.ac.uk/protall; 2001-10-15.
34. Wal, J. M. (1999). Assessment of allergic potential of (novel) foods. Nahrung 43, 168-174.