Allergenicity assessment of foods derived from genetically modified plants

Food Technology

Volumn 50, Issue 2, 1996, Pages 83-88

  Fuchs, Roy L ^a   Astwood, James D ^a  

^a MONSANTO COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0002810940     PISSN: 00156639     EISSN: None     Source Type: Trade Journal    
DOI: None     Document Type: Article

References (70)

1. Anonymous. 1990. "The United States Pharmacopeia, Vol. XMII, N-F XVII." United States Pharmacopeial Convention, Inc., Rockville, Md.
2. Anonymous. 1994. Transcripts from the Conference on Scientific Issues Related to Potential Allergenicity in Transgenic Food Crops." Docket 94N-0053, Food and Drug Admin., Washington, D.C.
3. Arshad, S.H., Malmberg, E., Kraft, K., and Hide, D.W. 1991. Clinical and immunological characteristics of Brazil nut allergy. Clin. Exp. Allergy 21: 373-376.
4. Asselin, J., Amiot, J., Gauthier, S.F., Mourad,W., and Hebert, J. 1988. Immunogenicity and allergenicity of whey protein hydrolysates. J. Food Sci. 53: 1208-1211.
5. Asselin, J., Hebert, J., and Amiot, J. 1989. Effects of in vitro proteolysis on the allergenicity of major whey proteins. J. Food Sci. 54: 1037-1039.
6. Astwood, J.D. 1995. Unpublished data. Dept. of Regulatory Science, Monsanto Co., St. Louis.
7. Astwood, J.D., Mohapatra, S.S., Ni, H., and Hill, R.D. 1995. Pollen allergen homologues in barley and other crop species. Clin. Exp. Allergy 25: 150-157.
8. Baldo, BA. 1984. Milk Allergies. Austral. J. Dairy Technol. 39: 120-128.
9. Barnett, D, and Howden, M.E.H. 1986. Partial characterization of an allergenic glycoprotein from peanut (Arachis hypogaea L.). Biochem. Biophys. Acta 882: 97-105.
10. Barnett, D., Baldo, B.A., and Howden, M.E.H. 1983. Multiplicity of allergens in peanuts. J. Allergy Clin. Immunol. 72: 61-68.
11. Burks, A.W. and Fuchs, R.L. 1995. Assessment of the endogenous allergens in glyphosate-tolerant and commercial soybean varieties. J. Allergy Clin. Immunol. In press.
12. Burks, A.W., Sampson, H.A., and Buckley, R.H. 1986. Anaphylactic reactions following gammaglobulin administration in patients with hypogammaglobulinemia: Detection of IgE antibodies to IgA. New Eng. J. Med. 314: 560-564.
13. Burks, A.W., Brooks, J.R., and Sampson, H.A. 1988. Allergenicity of major component proteins of soybean determined by enzyme-linked immunosorbent assay (ELISA) and immunoblotting in children with atopic dermatitis and positive soy challenges. J. Allergy Clin. Immunol. 81: 1135-1142.
14. Burks, A.W., Cockrell, G., Connaughton, C., Guin, J., Allen, W., and Helm, R.M. 1994. Identification of peanut agglutinin and soybean trypsin inhibitor as minor legume allergens. Intl. Arch. Allergy Immunol. 105: 143-149.
15. Bush, R.K., Taylor, S.L., Nordlee, J.A., and Busse, W.W. 1985. Soybean oil is not allergenic to soybean-sensitive individuals. J. Allergy Clin. Immunol. 76: 242-245.
16. Ciba-Geigy. 1994. Petition for determination of nonregulated status of Ciba Seeds' corn genetically engineered to express the Cry IA(b) protein from Bacillus thuringiensis subspecies kurstaki. Petition to USDA/APHIS.
17. Elsayed, S. and Apold, J. 1983. Immunochemical analysis of cod fish allergen M: Locations of the immunoglobulin binding sites as demonstrated by native and synthetic peptides. Allergy 38:449-459.
18. Elsayed, S., Apold, J., Holen, E., Vik, H., Florvaag, E., and Dybendal, T. 1991. The structural requirements of epitopes with IgE binding capacity demonstrated by three major allergens from fish, egg and tree pollen. Scand. J. Clin. Lab. Invest. 51: 17-31.
19. EPA. 1994. Proposed policy; Plant-pesticides subject to the Federal Insecticide, Fungicide, and Rodenticide Act and the Federal Food, Drug and Cosmetic Act. Environmental Protection Agency, Fed. Reg. 59: 60496-60518.
20. FDA. 1992. Statement of policy: Foods derived from new plant varieties. Food and Drug Admin., Fed. Reg. 57: 22984-23005.
21. Fiske, H.J. and Dandekar, A.M. 1993. The introduction and expression of transgenes in plants. Sci. Hort. 55: 5-36.
22. Fuchs, R.L., Ream, J.E., Hammond, B.C., Naylor, M.W., Leimbruber, R.M., and Berberich, S.A. 1993. Safety assessment of the neomycin phosphotransferase II (NPTII) protein. Bio/Tech. 11: 1543-1547.
23. Fuchs, R.L., Rogan, G.J., Keck, P.J., Love, S.L., and Lavrik, P.B. 1995. Safety evaluation of Colorado potato beetle-protected potatoes. In WHO (1995), pp. 63-78
24. Gardner, M.L.G. 1988. Gastrointestinal absorption of intact proteins. Ann. Rev. Nutr. 8: 329-50.
25. Gillespie, D.N., Nakajima, M.D.S., and Gleich, M.D. 1976. Detection of allergy to nuts by the radioallergosorbent tests. J. Allergy Clin. Immunol. 57: 302-309.
26. Halsey, A.B., Martin, M.E., Ruff, M.E., Jacobs, P.O., and Jacobs, R.L. 1986. Sunflower oil is not allergenic to sunflower seed-sensitive patients. J. Allergy Clin. Immunol. 78: 408-410.
27. Höfte, H. and Whiteley, H.H. 1989. Insecticidal crystal proteins of Bacillus thuringiensis. Microbiol. Rev. 53: 242-255.
28. Kemp, A.S., Mellis, C.M., Barnett, D., Sharota, E., and Simpson, J. 1985. Skin test, RAST and clinical reactions to peanut allergens in children. Clin. Allergy 15: 73-78.
29. King, T.P., Norman, P.S., and Connell, J.J. 1967. Isolation and characterization of allergens from ragweed pollen, IV. Biochemistry 6: 1992-2000.
30. King, T.P., Hoffman, D., Lowenstein, H., Marsh, D.G., Platts-Mills, T.A.E., and Thomas, W. 1994. Allergen nomenclature. Intl. Arch. Allergy Immunol. 105: 224-233.
31. Kortekangas-Savolainen, O., Savolainen, J., and Einarsson, R. 1993. Gastrointestinal stability of baker's yeast allergens: An in vitro study. Clin. Exp. Allergy 23: 587-590.
32. Langeland, T. 1982. A clinical and immunological study of allergy to hen's egg white. III. Allergens in hen's egg white studies by crossed radioimmunoelectrophoresis (CRIE). Allergy 37: 521-530.
33. Lebenthal, E. 1975. Cow's milk protein allergy. Pediatr. Clinics N. Am. 22: 827-833.
34. Marquez, U.M.L. and Lajolo, FM. 1981. Composition and digestibility of albumins, globulins, and glutelins from Phaseolus vulgaris. J. Agric. Food Chem. 29: 1068-1074.
35. Matsuda, T., Alvarez, A.M., and Tada, Y. 1993. Gene engineering for hypo-allergenic rice: Repression of allergenic protein synthesis in seeds of transgenic rice plants by antisense RNA. In Proc. of Intl. Workshop on Life Science in Production and Food - Consumption of Agricultural Products, Tsukuba, Japan, Oct. 24-28.
36. Metcalfe, D.D. 1985. Food allergens. Clin. Rev. Allergy 3: 331-349.
37. Metcalfe, D.D. 1992. The nature and mechanisms of food allergies and related diseases. Food Technol. 46: 136-139.
38. Nielson, S.S. 1988. Degradation of bean proteins by endogenous and exogenous proteases - A review. Cereal Chem. 65: 435-442.
39. Nordlee, J.A., Taylor, S.L., Townsend, J.A., and Thomas, L.A. 1994. High methionine Brazil nut protein binds human IgE. J. Allergy Chn. Immunol. 93: 209.
40. Nordlee, J.A., Taylor, S.L., Townsend, J.A., Thomas, L.A., and Townsend, R. 1995. Investigations of the allergenicity of Brazil nut 2S storage protein in transgenic soybean. In Proc. of OECD Workshop on Food Safety Evaluation, Oxford, England. Sept. 12-15, 1994. pp. 121-125
41. Noteborn, H.P.J.M. and Kuiper, H.A. 1995. Safety evaluation of transgenic tomatoes expressing Bt endotoxin. In "Application of the Principles of Substantial Equivalence to the Safety Evaluation of Foods and Food Components from Plants Derived by Modern Biotechnology, pp. 51-62. World Health Org., Food Safety Unit, Geneva, Switzerland.
42. OECD. 1995. Proc. of Workshop on Safety Evaluation of Foods, Environmental Health and Safety Div., Org. for Economic Cooperation and Development, Paris.
43. Ogawa, T., Bando, N., Tsuji, H., Okajima, H., Nishikawa, K., and Sasaoka. K. 1991. Investigation of the IgE binding proteins in soybeans by immunoblotting with the sera of the soybean-sensitive patients with atopic dermatitis. J. Nutr. Sci. Vitarmnol. 37: 555-565.
44. O'Hehir, R.E., Garman, R.D., Greenstein, J.L., and Lamb, J.R. 1991. The specificity and regulation of T-cell responsiveness to allergens. Ann. Rev. Immunol. 9: 67-95.
45. Onaderra, M., Monsalve, R.I., Mancheno, J.M., Villalba, M., Martinez Del Pozo A., Gavilanes, G., and Rodriguez, R. 1994. Food mustard allergen interaction with phospholipid vesicles. Eur. J. Biochem. 225: 609-615.
46. Padgette, S.R., Re, D.B., Barry, G.F., Eichholtz, D.E., Delannay, X., Fuchs, R.L., Kishore, G.M., and Fraley, R.T. 1996. New weed control opportunities: Development of soybeans with roundup tolerance. In "Herbicide-Resistant Crops: Agricultural, Economic, Environmental, Regulatory and Technological Aspects," ed. S.O. Duke, pp. 53-84. CRC Press, Boca Raton, Fla.
47. Pearson, W. and Lipman, D. 1988. Improved tools for biological sequence comparison. Proc. Natl. Acad. Sci. USA 85: 2444-2448.
48. Pederson, H.S. and Djurtoft. R. 1989. Antigenic and allergenic properties of acidic and basic peptide chains from glycinin. Food Agric. Immunol. 1: 101-109.
49. Perlak, F.J., Fuchs, R.L., Dean, D.A., McPherson S.L., and Fischhoff, D.A. 1991. Modification of the coding sequence enhances plant expression of insect cotton protein genes. Proc. Natl. Acad. Sci. USA 88: 3324-3328.
50. Perlak, F., Stone, T.B., Muskopf, Y.M., Petersen, L.J., Parker, G.B., McPherson, S.A, Wyman, J., Love, S., Reed, G., Biever, D., and Fischhoff, D. 1993. Genetically improved potatoes - Protection from damage by Colorado potato beetles. Plant Molec. Biol. 22: 313-321.
51. Reed, A.J., Magin, KM., Anderson, J.S., Austin, G.A., Rangwala, T., Linde, D.C., Love, J.N., Rogers, S.G., and Fuchs, R.L. 1995. Delayed ripening tomato plants expressing the enzyme 1-aminocyclopropane-1-carboxylic acid deaminase: I. Molecular characteristics, enzyme expression and fruit ripening traits. J. Agric. Food Chem. In press.
52. Rothbard, J.B. and Gefter, M.L. 1991. Interactions between immunogenic peptides and MHC proteins. Ann. Rev. Immunol. 9: 527-565.
53. Sachs, M.I., Jones, R.T., and Yunginger, J.W. 1981. Isolation and partial characterization of major peanut allergen. J. Allergy Clin. Immunol. 67: 27-34.
54. Sampson, H.A. 1992. Food hypersensitivity: Manifestations, diagnosis, and natural history. Food Technol. 46: 141-144.
55. Sampson, H.A. and Albergo, R. 1984. Comparison of results of skin tests, RAST, and double-blind placebo-controlled food challenges in children with atopic dermatitis. J. Allergy Clin. Immunol. 74: 26-33.
56. Savilahti, E. and Kuitunen, M. 1992. Allergenicity of cow milk proteins. J. Pediatr. 121: s12-s20.
57. Sheehy, R.E., Kramer, M., and Hiatt, W.R. 1988. Reduction of polygalacturonase in tomato fruit by antisense RNA. Proc. Natl. Acad. Sci. USA 85: 8805-8809.
58. Shibasaki, M., Suzuki, S., Tajima, S., Nemoto, H., and Kuroume, T. 1980. Allergenicity of major component proteins of soybean. Intl. Arch. Allergy Appl. Immunol. 61: 441-448.
59. Smith, A.M. and Chapman, M.D. 1995. Reduction of IgE antibody binding to rder p 2 variants generated by site-directed mutagenesis. Paper 42 presented at Intl. Symp. on Molecular Biology of Allergens and the Atopic Immune Response, Quebec, Feb 18.
60. Tattrie, N.H. and Yaguchi, M. 1973. Protein content of various processed edible oils. J. Inst. Can. Sci. Technol. Aliment 6: 289-290.
61. Taylor, S.L. 1986. Immunologic and allergic properties of cows' milk proteins in humans. J. Food Protect. 49: 239-250.
62. Taylor, S.L. 1992. Chemistry and detection of food allergens. Food Technol. 39: 146-152.
63. Taylor, S.L., Busse,W.W., Sachs, M.I., Parker, J.L., and Yunginger, J.W. 1981. Peanut oil is not allergenic to peanut-sensitive individuals. J. Allergy Clin. Immunol. 68: 372-375.
64. Taylor, S.L., Lemanske, R.F. Jr., Bush, R.M, and Busse, W.W. 1987. Food allergens: Structure and immunologic properties. Ann. Allergy 59: 93-99.
65. Taylor, S.L., Nordlee, J.A., and Bush, R.K. 1992. Food allergies. In "Food Safety Assessment," ACS Symp. Series 484, ed. J.W. Finley, S.F. Robinson, and D.J. Armstrong, pp. 316-329. Am. Chem. Soc., Washington, D.C.
66. Tilch, C. and Elias, P.S. 1984. Investigation of the mutagenicity of ethyl phenylglycidate. Mut. Res. 138: 1-8.
67. WHO. 1993. Health aspects of marker genes in genetically modified plants. World Health Org., Food Safety Unit, Geneva, Switzerland.
68. WHO. 1995. Application of the principles of substantial equivalence to the safety evaluation of foods and food components from plants derived by modern biotechnology. World Health Org., Food Safety Unit, Geneva, Switzerland.
69. Zhang, L, Olsen, E., Kisil, F.T., Hill, R.D., Sehon, A.H., and Mohapatra, S.S. 1992. Mapping of antibody binding epitopes of a recombinant Poa p IX allergen. Molec. Immun. 29: 1383-1389.
70. Zikakis, J.P., Rzucidlo, S.J., and Biasotto, N.O. 1977. Persistance of bovine milk xanthine oxidase activity after gastric digestion in vivo and in vitro. J. Dairy Sci. 60: 533-541.