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Volumn 184, Issue 6 SUPPL. 1, 2002, Pages S47-S50

Conclusions: Drotrecogin alfa (activated) - From bench to practical use at the bedside

Author keywords

[No Author keywords available]

Indexed keywords

DROTRECOGIN;

EID: 0036935265     PISSN: 00029610     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0002-9610(02)01136-4     Document Type: Article
Times cited : (1)

References (34)
  • 1
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
    • Angus D.C., Linde-Zwirble W.T., Lidicker J., et al. Epidemiology of severe sepsis in the United States analysis of incidence, outcome, and associated costs of care . Crit Care Med. 29:2001;1303-1310.
    • (2001) Crit Care Med , vol.29 , pp. 1303-1310
    • Angus, D.C.1    Linde-Zwirble, W.T.2    Lidicker, J.3
  • 2
    • 0033054742 scopus 로고    scopus 로고
    • Clinical trials for severe sepsis: Past failures and future hopes
    • Opal S.M., Cross A.S. Clinical trials for severe sepsis past failures and future hopes . Infect Dis Clin North Am. 13:1999;285-297.
    • (1999) Infect Dis Clin North Am , vol.13 , pp. 285-297
    • Opal, S.M.1    Cross, A.S.2
  • 3
    • 0023239471 scopus 로고
    • Effect of high-dose glucocorticoid therapy on mortality in patients with signs of systemic sepsis
    • Effect of high-dose glucocorticoid therapy on mortality in patients with signs of systemic sepsis. N Engl J Med. 317:1987;659-665.
    • (1987) N Engl J Med , vol.317 , pp. 659-665
  • 4
    • 0023252009 scopus 로고
    • A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock
    • Bone R.C., Fisher C.J. Jr, Clemmer T.P., et al. A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock. N Engl J Med. 317:1987;653-658.
    • (1987) N Engl J Med , vol.317 , pp. 653-658
    • Bone, R.C.1    Fisher C.J., Jr.2    Clemmer, T.P.3
  • 5
    • 0034607323 scopus 로고    scopus 로고
    • E5 murine monoclonal antiendotoxin antibody in gram-negative sepsis: A randomized controlled trial. E5 Study Investigators
    • Angus D.C., Birmingham M.C., Balk R.A., et al. E5 murine monoclonal antiendotoxin antibody in gram-negative sepsis a randomized controlled trial. E5 Study Investigators . JAMA. 283:2000;1723-1730.
    • (2000) JAMA , vol.283 , pp. 1723-1730
    • Angus, D.C.1    Birmingham, M.C.2    Balk, R.A.3
  • 6
    • 0028557981 scopus 로고
    • Treatment of septic shock with human monoclonal antibody HA-1A. A randomized, double-blind, placebo-controlled trial. CHESS Trial Study Group
    • McCloskey R.V., Straube R.C., Sanders C., et al. Treatment of septic shock with human monoclonal antibody HA-1A. A randomized, double-blind, placebo-controlled trial. CHESS Trial Study Group. Ann Intern Med. 121:1994;1-5.
    • (1994) Ann Intern Med , vol.121 , pp. 1-5
    • McCloskey, R.V.1    Straube, R.C.2    Sanders, C.3
  • 7
    • 0028957549 scopus 로고
    • Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis syndrome. A randomized, controlled, double-blind, multicenter trial. TNF-alpha MAb Sepsis Study Group
    • Abraham E., Wunderink R., Silverman H., et al. Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis syndrome. A randomized, controlled, double-blind, multicenter trial. TNF-alpha MAb Sepsis Study Group. JAMA. 273:1995;934-941.
    • (1995) JAMA , vol.273 , pp. 934-941
    • Abraham, E.1    Wunderink, R.2    Silverman, H.3
  • 8
    • 0034913364 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor therapy in sepsis: Update on clinical trials and lessons learned
    • Reinhart K., Karzai W. Anti-tumor necrosis factor therapy in sepsis update on clinical trials and lessons learned . Crit Care Med. 29:(suppl):2001;S121-S125.
    • (2001) Crit Care Med , vol.29 , Issue.SUPPL.
    • Reinhart, K.1    Karzai, W.2
  • 9
    • 0030746482 scopus 로고    scopus 로고
    • Anti-inflammatory therapies to treat sepsis and septic shock: A reassessment
    • Zeni F., Freeman B., Natanson C. Anti-inflammatory therapies to treat sepsis and septic shock a reassessment . Crit Care Med. 25:1997;1095-1100.
    • (1997) Crit Care Med , vol.25 , pp. 1095-1100
    • Zeni, F.1    Freeman, B.2    Natanson, C.3
  • 10
    • 0026534242 scopus 로고
    • Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of antithrombin III, protein C, and protein S deficiencies
    • Fourrier F., Chopin C., Goudemand J., et al. Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of antithrombin III, protein C, and protein S deficiencies. Chest. 101:1992;816-823.
    • (1992) Chest , vol.101 , pp. 816-823
    • Fourrier, F.1    Chopin, C.2    Goudemand, J.3
  • 11
    • 0033810792 scopus 로고    scopus 로고
    • Protein C levels as a prognostic indicator of outcome in sepsis and related diseases
    • Fisher C.J., Yan S.B. Protein C levels as a prognostic indicator of outcome in sepsis and related diseases. Crit Care Med. 28:2000;S49-S56.
    • (2000) Crit Care Med , vol.28
    • Fisher, C.J.1    Yan, S.B.2
  • 12
    • 0033860427 scopus 로고    scopus 로고
    • Prognostic value of protein C levels in neutropenic patients at high risk of severe septic complications
    • Mesters R.M., Helterbrand J., Utterback B.G., et al. Prognostic value of protein C levels in neutropenic patients at high risk of severe septic complications. Crit Care Med. 28:2000;2209-2216.
    • (2000) Crit Care Med , vol.28 , pp. 2209-2216
    • Mesters, R.M.1    Helterbrand, J.2    Utterback, B.G.3
  • 13
    • 0034834039 scopus 로고    scopus 로고
    • Low levels of protein C are associated with poor outcome in severe sepsis
    • Yan S.B., Helterbrand J.D., Hartman D.L., et al. Low levels of protein C are associated with poor outcome in severe sepsis. Chest. 120:2001;915-922.
    • (2001) Chest , vol.120 , pp. 915-922
    • Yan, S.B.1    Helterbrand, J.D.2    Hartman, D.L.3
  • 14
    • 0026591793 scopus 로고
    • The protein C anticoagulant pathway
    • Esmon C.T. The protein C anticoagulant pathway. Arterioscler Thromb. 12:1992;135-145.
    • (1992) Arterioscler Thromb , vol.12 , pp. 135-145
    • Esmon, C.T.1
  • 15
    • 0033815369 scopus 로고    scopus 로고
    • The protein C pathway
    • Esmon C.T. The protein C pathway. Crit Care Med. 28:2000;S44-S48.
    • (2000) Crit Care Med , vol.28
    • Esmon, C.T.1
  • 16
    • 0035826096 scopus 로고    scopus 로고
    • Efficacy and safety of recombinant human activated protein C for severe sepsis
    • Bernard G.R., Vincent J.L., Laterre P.F., et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med. 344:2001;699-709.
    • (2001) N Engl J Med , vol.344 , pp. 699-709
    • Bernard, G.R.1    Vincent, J.L.2    Laterre, P.F.3
  • 19
    • 0000979612 scopus 로고
    • The quantitative relation between platelet count and hemorrhage in patients with acute leukemia
    • Gaydos L.A., Freireich E.J., Mantel N. The quantitative relation between platelet count and hemorrhage in patients with acute leukemia. N Engl J Med. 266:1962;905-909.
    • (1962) N Engl J Med , vol.266 , pp. 905-909
    • Gaydos, L.A.1    Freireich, E.J.2    Mantel, N.3
  • 20
    • 0032741081 scopus 로고    scopus 로고
    • Optimal dosing and triggers for prophylactic use of platelet transfusions
    • Rinder H.M., Arbini A.A., Snyder E.L. Optimal dosing and triggers for prophylactic use of platelet transfusions. Curr Opin Hematol. 6:1999;437-441.
    • (1999) Curr Opin Hematol , vol.6 , pp. 437-441
    • Rinder, H.M.1    Arbini, A.A.2    Snyder, E.L.3
  • 21
    • 0141610906 scopus 로고    scopus 로고
    • The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting
    • Ibrahim E.H., Sherman G., Wad S., et al. The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting. Chest. 118:2000;146-155.
    • (2000) Chest , vol.118 , pp. 146-155
    • Ibrahim, E.H.1    Sherman, G.2    Wad, S.3
  • 22
    • 0037018951 scopus 로고    scopus 로고
    • The commonality of risk factors for nosocomial colonization/ infection with antimicrobial-resistant Staphylococus aureus, Enterococcus, gram-negative bacilli, Clostridium difficile and Candida
    • Safdar N., Maki D.G. The commonality of risk factors for nosocomial colonization/ infection with antimicrobial-resistant Staphylococus aureus, Enterococcus, gram-negative bacilli, Clostridium difficile and Candida. Ann Intern Med. 136:2002;834-844.
    • (2002) Ann Intern Med , vol.136 , pp. 834-844
    • Safdar, N.1    Maki, D.G.2
  • 23
    • 0000317718 scopus 로고    scopus 로고
    • Management of life-threatening infection in the intensive care unit
    • M.J. Murray, D.B. Coursin, R.G. Pearl, & D.S. Prough. Philadelphia: Lippincott Williams & Wilkins. 50:
    • Maki D.G. Management of life-threatening infection in the intensive care unit. Murray M.J., Coursin D.B., Pearl R.G., Prough D.S. Critical Care Medicine: Preoperative Management. 2nd ed. 2002;616-648 Lippincott Williams & Wilkins, Philadelphia. 50:
    • (2002) Critical Care Medicine: Preoperative Management 2nd ed. , pp. 616-648
    • Maki, D.G.1
  • 24
    • 0034922339 scopus 로고    scopus 로고
    • Source control in the management of sepsis
    • Jimenez M.F., Marshall J.C. Source control in the management of sepsis. Intensive Care Med. 27:(suppl 1):2001;S49-S62.
    • (2001) Intensive Care Med , vol.27 , Issue.SUPPL. 1
    • Jimenez, M.F.1    Marshall, J.C.2
  • 25
    • 0034036640 scopus 로고    scopus 로고
    • Pathogenesis and management of multiple organ dysfunction or failure in severe sepsis and septic shock
    • Balk R.A. Pathogenesis and management of multiple organ dysfunction or failure in severe sepsis and septic shock. Crit Care Clin. 16:2000;337-352.
    • (2000) Crit Care Clin , vol.16 , pp. 337-352
    • Balk, R.A.1
  • 26
    • 0033590515 scopus 로고    scopus 로고
    • Treating patients with severe sepsis
    • Wheeler A.P., Bernard G.R. Treating patients with severe sepsis. N Engl J Med. 340:1999;207-214.
    • (1999) N Engl J Med , vol.340 , pp. 207-214
    • Wheeler, A.P.1    Bernard, G.R.2
  • 27
    • 0032574523 scopus 로고    scopus 로고
    • Fluid resuscitation with colloid or crystalloid solutions in critically ill patients: A systematic review of randomised trials
    • Schierhout G., Roberts I. Fluid resuscitation with colloid or crystalloid solutions in critically ill patients a systematic review of randomised trials . BMJ. 316:1998;961-964.
    • (1998) BMJ , vol.316 , pp. 961-964
    • Schierhout, G.1    Roberts, I.2
  • 28
    • 0033527033 scopus 로고    scopus 로고
    • Effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis
    • Sort P., Navasa M., Arroyo V., et al. Effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis. N Engl J Med. 341:1999;403-409.
    • (1999) N Engl J Med , vol.341 , pp. 403-409
    • Sort, P.1    Navasa, M.2    Arroyo, V.3
  • 29
    • 0035829842 scopus 로고    scopus 로고
    • Early goal-directed therapy in the treatment of severe sepsis and septic shock
    • Rivers E., Nguyen B., Havstad S., et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med. 345:2001;1368-1377.
    • (2001) N Engl J Med , vol.345 , pp. 1368-1377
    • Rivers, E.1    Nguyen, B.2    Havstad, S.3
  • 30
    • 0020960312 scopus 로고
    • Optimum left heart filling pressure during fluid resuscitation of patients with hypovolemic and septic shock
    • Packman M.I., Rackow E.C. Optimum left heart filling pressure during fluid resuscitation of patients with hypovolemic and septic shock. Crit Care Med. 11:1983;165-169.
    • (1983) Crit Care Med , vol.11 , pp. 165-169
    • Packman, M.I.1    Rackow, E.C.2
  • 31
    • 0343360868 scopus 로고    scopus 로고
    • A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care
    • Hebert P.C., Wells G., Blajchman M.A., et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med. 340:1999;409-417.
    • (1999) N Engl J Med , vol.340 , pp. 409-417
    • Hebert, P.C.1    Wells, G.2    Blajchman, M.A.3
  • 32
    • 8044242942 scopus 로고    scopus 로고
    • Applied nutrition in ICU patients. A consensus statement of the American College of Chest Physicians
    • Cerra F.B., Benitez M.R., Blackburn G.L., et al. Applied nutrition in ICU patients. A consensus statement of the American College of Chest Physicians. Chest. 111:1997;769-778.
    • (1997) Chest , vol.111 , pp. 769-778
    • Cerra, F.B.1    Benitez, M.R.2    Blackburn, G.L.3
  • 33
    • 0034066040 scopus 로고    scopus 로고
    • The effect of nutritional supplementation on survival in seriously ill hospitalized adults: An evaluation of the SUPPORT data
    • Borum M.L., Lynn J., Zhong Z., et al. The effect of nutritional supplementation on survival in seriously ill hospitalized adults an evaluation of the SUPPORT data . J Am Geriatr Soc. 48:(5 suppl):2000;S33-S38.
    • (2000) J Am Geriatr Soc , vol.48 , Issue.5 SUPPL.
    • Borum, M.L.1    Lynn, J.2    Zhong, Z.3
  • 34
    • 0035829852 scopus 로고    scopus 로고
    • Intensive insulin therapy in critically ill patients
    • Van den Berghe G., Woutors P., Weekers F., et al. Intensive insulin therapy in critically ill patients. N Engl J Med. 345:2001;1368-1377.
    • (2001) N Engl J Med , vol.345 , pp. 1368-1377
    • Van den Berghe, G.1    Woutors, P.2    Weekers, F.3


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