Management of women with cervical cancer precursor lesions

Obstetrics and Gynecology Clinics of North America

Volumn 29, Issue 4, 2002, Pages 787-816

  Cox, J Thomas ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; FLUOROURACIL;

ALGORITHM; CANCER GRADING; COLPOSCOPY; CRYOTHERAPY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST; DISEASE COURSE; FEMALE; FOLLOW UP; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HYSTERECTOMY; IMMUNE RESPONSE; OBSERVER VARIATION; PAPANICOLAOU TEST; PRACTICE GUIDELINE; PRECANCER; PRIORITY JOURNAL; REVIEW; SENSITIVITY AND SPECIFICITY; UTERINE CERVIX CANCER; UTERINE CERVIX CARCINOMA IN SITU; WART VIRUS;

CERVICAL INTRAEPITHELIAL NEOPLASIA; FEMALE; HEALTH BEHAVIOR; HUMANS; PRACTICE GUIDELINES; UTERINE CERVICAL NEOPLASMS;

EID: 0036924922     PISSN: 08898545     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0889-8545(02)00047-5     Document Type: Review

References (134)

1. Peng YM, Peng YS, Childers JM, Hatch KD, Roe DJ, Lin Y, et al. Concentrations of carotenoids, tocopherols, and retinol in paired plasma and cervical tissue of patients with cervical cancer, precancer, and noncancerous diseases. Cancer Epidemiol Biomarkers Prev 1998;7:347-50.
2. Palan PR, Mikhail MS, Goldberg GL, Basu J, Runowicz CD, Romney SL. Plasma levels of beta-carotene, lycopene, canthaxanthin, retinol, and alpha- and tau-tocopherol in cervical intraepithelial neoplasia and cancer. Clin Cancer Res 1996;2:181-5.
3. Comerci Jr JT, Runowicz CD, Fields AL, Romney SL, Palan PR, Kadish AS, et al. Induction of transforming growth factor beta-1 in cervical intraepithelial neoplasia in vivo after treatment with beta-carotene. Clin Cancer Res 1997;3:157-60.
4. Lehtinen M, Luostarinen T, Youngman LD, Anttila T, Dillner J, Hakulinen T, et al. Low levels of serum vitamins A and E in blood and subsequent risk for cervical cancer: Interaction with HPV seropositivity. Nutr Cancer 1999;34:229-34.
5. Sedjo RL, Inserra P, Abrahamsen M, Harris RB, Roe DJ, Baldwin S, et al. Human papillomavirus persistence and nutrients involved in the methylation pathway among a cohort of young women. Cancer Epidemiol Biomarkers Prev 2002;11:353-9.
6. Alberg AJ, Selhub J, Shah KV, Viscidi RP, Comstock GW, Helzlsouer KJ. The risk of cervical cancer in relation to serum concentrations of folate, vitamin B12, and homocysteine. Cancer Epidemiol Biomarkers Prev 2000;9:761-4.
7. Palan PR, Chang CJ, Mikhail MS, Ho GY, Basu J, Romney SL. Plasma concentrations of micronutrients during a nine-month clinical trial of beta-carotene in women with precursor cervical cancer lesions. Nutr Cancer 1998;30:46-52.
8. Moore TO, Moore AY, Carrasco D, Vander Straten M, Arany I, Au W, et al. Human papillomavirus, smoking, and cancer. J Cutan Med Surg 2001;5:323-8.
9. Acladious NN, Sutton C, Mandal D, Hopkins R, Zaklama M, Kitchener H. Persistent human papillomavirus infection and smoking increase risk of failure of treatment of cervical intraepithelial neoplasia (CIN). Int J Cancer 2002;98:435-9.
10. Bjork S, Hagstrom HG. Of what significance is abnormal result of smear test? Anxiety because of insufficient information in connection with abnormal result of cervical smear test. Lakartidningen 2001;98:2796-800.
11. Jones MH, Singer A, Jenkins D. The mildly abnormal cervical smear: Patient anxiety and choice of management. J R Soc Med 1996;89:257-60.
12. Marteau TM. Psychological effects of an abnormal smear result. In: Prendiville W, editor. Large Loop Excision of the Transformation Zone: A Practical Guide to LLETZ. London: Chapman and Hall; 1993. p. 65-72.
13. Doherty IE, Richardson PH. Psychological ascpects of the investigation and treatment of abnormalities of the cervix. In: Luesley D, Jordan J, Richart R, editors. Intraepithelial Neoplasia of the Lower Genital Tract. London: Livingston Ltd; 1995. p. 241-50.
14. Wilkinson C, Jones IM, McBridge J. Anxiety caused by abnormal result of a cervical smear test: A controlled trial. BMJ 1990;300:440.
15. Fallowfield LJ. Counseling for patients with cancer. BMJ 1988;297:727-28.
16. Wright TC, Cox JT, Massad LS, Carlson J, Wilkinson EJ. for the 2001 ASCCP-Sponsored Consensus Workshop. 2001 Consensus Guidelines for the Management of Women with Cervical Cytological Abnormalities and Cervical Cancer Precursors - Part II: Histological Abnormalities (submitted for publication).
17. Nuovo GJ, Banbury R, Calayag PT. Human papillomavirus types and recurrent cervical warts in immunocompromised women. Mod Pathol 1991;4:632-5.
18. Cox JT. Management of cervical intraepithelial neoplasia. Lancet 1999;353:857-9.
19. Ferenczy A, Choukroun D, Arseneau J. Loop electrosurgical excision procedure for squamous intraepithelial lesions of the cervix: Advantages and potential pitfalls. Obstet Gynecol 1996;87:332-7.
20. Wright TC, Gagnon S, Richart RM, Ferenczy A. Treatment of cervical intraepithelial neoplasia using the loop electrosurgical excision procedure. Obstet Gynecol 1992;79:173-8.
21. Mitchell MF, Tortolero-Lunn G, Cook E, et al. A randomized clinical trial of cryotherapy, loop electrosurgical excision for treatment of squamous intraepithelial lesions of the cervix. Obstet Gyneol 1998;92:737-44.
22. Kwikkel HJ, Helmerhorst TJM, Bezemer PD, Quaak MJ, Stolk JG. Laser or cryotherapy for cervical intraepithelial neoplasia: A randomized study to compare efficacy and side effects. Gynecol Oncol 1985;22:23-31.
23. Ferenczy A. Comparison of cryo and carbon dioxide laser therapy for cervical intraepithelial neoplasia. Obstet Gynecol 1985;66:793.
24. 2 laser versus cryotherapy, a randomized clinical trial. Acta Obstet Gynecol Scand 1987;66:531-6.
25. 2 laser in treatment of carcinoma in situ (CIN III) of the uterine cervix. Gynecol Oncol 1985;22:195.
26. Townsend DE, Richart RM. Cryotherapy and carbon-dioxide laser management of cervical intraepithelial neoplasia: A controlled comparison. Obstet Gynecol 1983;61:75-8.
27. Berget A, Andreasson B, Bock JE. Laser and cryosurgery for cervical intraepithelial neoplasia: A randomized trial and long-term follow-up. Acta Obstet Gynecol Scand 1991;70:231-5.
28. Alvarez RD, Helm CW, Edwards RP, Naumann RW, Partridge EE, Shingleton HM, et al. Prospective randomized trial of LLETZ versus laser ablation in patients with cervical intraepithelial neoplasia. Gynecol Oncol 1994;52:175-9.
29. Wright VC, Daris EM. The conservative management of cervical intraepithelial neoplasia: The use of cryosurgery and the carbon dioxide laser. B R J Obstet Gynecol 1981;88:663-8.
30. Gunasekera PC, Phipps JH, Lewis BV. Large-loop excision of the transformation zone (LLETZ) compared to carbon dioxide laser in the treatment of CIN: A superior mode of treatment. Br J Obstet Gynaecol 1990;97:995-8.
31. Martin-Hirsch PL, Paraskevaidis E, Kitchener H. Surgery for cervical intraepithelial neoplasia. Cochrane Database Syst Rev 2000;2:13-8.
32. Buxton EI, Luesley DM, Shafi MI, Rollason M. Colposcopically directed punch biopsy: A potentially misleading investigation. Br J Obstet Gynaecol 1991;98:1273.
33. McIndoe A, Robson M, Tidy J, Mason P, Anderson M. Laser excision rather than vaporization: The treatment of choice for cervical intraepithelial neoplasia. Obstet Gynecol 1989;74:165.
34. Sze E, Rosenzweig B, Birenbaum D, et al. Excisional conisation of the cervix-uteri. J Gynecol Surg 1989;5:325.
35. Giles JA, Walker PC, Chalk PA. The treatment of CIN by radical electrocoagulation diathermy: Five years' experience. Br J Obstet Gynaecol 1987;94:1089.
36. Hammond PH, Edmonds DK. Does treatment for cervical intraepithelial neoplasia affect fertility and pregnancy? Little to worry about. BMJ 1990;301:1344-5.
37. Montz FJ. Impact of therapy for cervical intraepithelial neoplasia on fertility. Am J Obstet Gynecol 1996;175:1129-36.
38. Wright TC, Cox JT, Massad LS, Twiggs LB, Wilkinson EJ for the 2001 ASCCP-Sponsored Consensus Workshop. 2001 Consensus guidelines for the management of women with cervical cytological abnormalities and cervical cancer precursors - Part I. cytological abnormalities. JAMA 2002;287:2120-9.
39. Richart RM, Barron BA. A follow-up study of patients cervical dysplasia. Am J Obstet Gynecol 1969;105:386-92.
40. Shafi MI, Luesley DM, Jordan JA, Dunn JA, Rollason TP, Yates M. Randomised trial of immediate versus deferred treatment strategies for the management of minor cervical cytological abnormalities. Br J Obstet Gynaecol 1997;104:590-4.
41. Cannistra SA, Niloff JM. Cancer of the uterine cervix. New Eng J Med 1996;334:1030-38.
42. Nasiell K, Nasiell M, Vaclavinkova V. Behavior of moderate cervical dysplasia during longterm follow-up. Obstet Gynecol 1983;61:609-14.
43. Ostor AG. Natural history of CIN: A critical review. Int J Gynecol Pathol 1993;12:186-92.
44. Stoler MH, Schiffman M. Interobserver reproducibility of cervical cytologic and histologic interpretations: Realistic estimates from the ASCUS-LSIL Triage Study. JAMA 2001;285:1500-5.
45. Guido R, Solomon D, Schiffman M, Burke L. Comparison of management strategies for women diagnosed as CIN 1 or less postcolposcopic evaluation: Data from the ASCUS and LSIL Triage Study (ALTS), a multicenter randomized trial [abstract]. J Low Gen Tract Dis 2002;6:176.
46. Jones MH, Jenkins D, Cuzick J, et al. Mild cervical dyskaryosis: Safety of cytological surveillance. Lancet 1992;339:1440-43.
47. Freeman-Wang T, Walker P, Linehan J, Coffey C, Glasser B, Sherr L. Anxiety levels in women attending colposcopy clinics for treatment for cervical intraepithelial neoplasia: A randomised trial of written and video information. BJOG 2001;108:482-4.
48. Holowaty P, Miller AB, Rohan T, To T. Natural history of dysplasia of the uterine cervix. J Natl Cancer Inst 1999;91:252-8.
49. Bosch FX, Lorincz A, Munoz N, Meijer CJLM, Shah KV. The causal relation between human papillomavirus and cervical cancer. J Clin Pathol 2002;55:244-65.
50. Nobbenhuis M, Walboomers JM, Helmerhorst T, Rozendaal L. Relation of human papillomavirus status to cervical lesions and consequences for cervical-cancer screening: A prospective study. Lancet 1999;354:20.
51. Solomon D, Schiffman MH, Tarone B for the ALTS Group. Comparison of three management strategies for patients with atypical squamous cells of undetermined significance: Baseline results from a randomized trial. National Cancer Inst 2001;93:293-9.
52. Robertson AJ, Anderson JM, Beck JS, et al. Observer variability in histopathological reporting of cervical biopsy specimens. J Clin Pathol 1989;42:231-8.
53. Ismail SM, Colelough AB, Dinnen JS, et al. Observer variation in histopathological diagnosis and grading of cervical intraepithelial neoplasia. BMJ 1989;298:707-10.
54. Roteli-Martin CM, Derchain SF, Martinez EZ, Siqueira SA, Alves VA, Syrjanen KJ. Morphological diagnosis of HPV lesions and cervical intraepithelial neoplasia (CIN) is highly reproducible. Clin Exp Obstet Gynecol 2001;28:78-80.
55. Shafi MI, Luesley DM. Management of low-grade lesions: Follow-up or treat? Baillieres Clin Obstet Gynaecol 1995;9:121-31.
56. Heatley MK. The prognosis in cervical epithelial changes of uncertain significance is similar to that of cervical intraepithelial neoplasia grade 1. J Clin Pathol 2001;54:474-5.
57. Etherington IJ, Luesley DM, Shafi MI, Dunn J, Hiller L, Jordan JA. Observer variability among colposcopists from the West Midlands region. Br J Obstet Gynaecol 1997;104:1380-4.
58. Sellors JW, Nieminen P, Vesterinen E, Paavonen J. Observer variability in the scoring of colpophotographs. Obstet Gynecol 1990;76:1006-8.
59. Hopman EH, Voorhorst FJ, Kenemans P, Meyer CJ, Helmerhorst TJ. Observer agreement on interpreting colposcopic images of CIN. Gynecol Oncol 1995;58:206-9.
60. Sideri M, Schettino F, Spinaci L, Spolti N, Crosignani P. Operator variability in disease detection and grading by colposcopy in patients with mild dysplastic smears. Cancer 1995;76:1601-5.
61. Kierkegaard O, Byrjalsen C, Frandsen KH, Hansen KC, Frydenberg M. Diagnostic accuracy of cytology and colposcopy in cervical squamous intraepithelial lesions. Acta Obstet Gynecol Scand 1994;73:648-51.
62. Howe DT, Vincenti AC. Is large loop excision of the transformation zone (LLETZ) more accurate than colposcopically directed punch biopsy in the diagnosis of cervical intraepithelial neoplasia? Br J Obstet Gynaecol 1991;98:588-91.
63. Evaluation of Cervical Cytology. Evidence Report/Technology Assessment No. 5. AHCPR Publication 99-E010; 1999.
64. Fahey MT, Irwig L, Macaskill P. Meta-analysis of Pap test accuracy. Am J Epidemiol 1995;141:680-89.
65. Nanda K, McCrory DC, Myers ER, Bastian LA, Hasselblad V, Hickey JD, et al. Accuracy of the Papanicolaou test in screening for and follow-up of cervical cytologic abnormalities: A systematic review. Ann Intern Med 2000;132:810-9.
66. Robertson JH, Woodend BE, Crozier EH, Hutcjhinson J. Risk of cervical cancer associated with mild dyskaryosis. BMJ 1988;297:18-21.
67. Cooper P, Kirby AJ, Spieglehalter DJ, et al. Management of women with a cervical smear showing a mild degree of dyskaryosis: A review of policy. Cytopathol 1993;3:331-339.
68. Fall RK. Spontaneous resolution rate of grade 1 cervical intraepithelial neoplasia in a private practice population. Am J Obstet Gynecol 1999;181:278-82.
69. Melnikow J, Nuovo J, Willan AR, Chan BK, Howell LP. Natural history of cervical squamous intraepithelial lesions: A meta-analysis. Obstet Gynecol 1998;92:727-35.
70. Duggan MA, McGregor SE, Stuart GC, Morris S, Chang-Poon V, Schepansky A, et al. The natural history of CIN I lesions. Eur J Gynaecol Oncol 1998;19:338-44.
71. Nasiell K, Roger V, Nasiell M. Behavior of mild cervical dysplasia during long-term follow-up. Obstet Gynecol 1986;67:665-69.
72. Luthra UK, Prabhakar AK, Seth P, et al. Natural history of precancerous and early cancerous lesions of the uterine cervix. Acta Cytol 1987;31:226-34.
73. Hartz LE, Fenaughty AM. Management choice and adherence to follow-up after colposcopy in women with cervical intraepithelial neoplasia 1. Obstet Gynecol 2001;98(4):674-8.
74. Abercrombie PD. Improving adherence to abnormal Pap smear follow-up. J Obstet Gynecol Neonatal Nurs 2001;30:80-8.
75. Duncan ID. NHS Cervical Screening Programme: Guidelines for Clinical Practice and Programme Management. Oxford: National Coordinating Network; 1992.
76. Nugent LS, Tamlyn-Leaman K, Isa N, Reardon E, Crumley J. Anxiety and the colposcopy experience. Clin Nurs Res 1993;2:267-77.
77. Bell S, Porter M, Kitchener H, Fraser C, Fisher P, Mann E. Psychological response to cervical screening. Prev Med 1995;24:610-6.
78. Posner T, Vessey M. Prevention of Cervical Cancer: The Patients View. London: Kings Fund; 1988.
79. Ramirez JE, Ramos DM, Clayton L, Kanowitz S, Moscicki AB. Genital human papillomavirus infections: Knowledge, perception of risk, and actual risk in a nonclinic population of young women. J Womens Health 1997;6:113-21.
80. Reed BD, Ruffin MT, Gorenflo DW, Zazove P. The psychosexual impact of human papillomavirus cervical infections. J Fam Pract 1999;48:110-6.
81. Clarke P, Ebel C, Catotti DN, Stewart S. The psychosocial impact of human papillomavirus infection: Implications for health care providers. Int J STD AIDS 1996;7:197-200.
82. Stewart DE, Lickrish GM, Sierra S, Parkin H. The effect of educational brochures on knowledge and emotional distress in women with abnormal Papanicolaou smears. Obstet Gynecol 1993;81:280-2.
83. Meana M, Stewart DE, Lickrish GM, Murphy J, Rosen B. Patient preference for the management of mildly abnormal Papanicolaou smears. J Womens Health Gend Based Med 1999;8:941-7.
84. Kavanagh AM, Broom DH. Women's understanding of abnormal cervical smear test results: A qualitative interview study. BMJ 1997;314:1388-91.
85. Hamm RM, Loemker V, Reilly KL, Johnson G, Dubois P, Staveley-O'Carroll K, et al. A clinical decision analysis of cryotherapy compared with expectant management for cervical dysplasia. J Fam Pract 1998;47:193-201.
86. Wright TC, Ferenczy AF, Kurman RJ. Precancerous lesions of the cervix. In: Kurman RJ, editor. Blaustein's Pathology of the Female Genital Tract. 4th Edition. New York: SpringerVerlag; 1994. p. 229-78.
87. Spitzer M, Chernys AE, Shifrin A, Ryskin M. Indications for cone biopsy: Pathologic correlation. Am J Obstet Gynecol 1998;178:74-9.
88. Jones BA, Davey DD. Quality management in gynecologic cytology using interlaboratory comparison. Arch Pathol Lab Med 2000;124:672-81.
89. Fine BA, Feinstein GI, Sabella V. The pre- and postoperative value of endocervical curettage in the detection of cervical intraepithelial neoplasia and invasive cervical cancer. Gynecol Oncol 1998;71:46-9.
90. Kobak WH, Roman LD, Felix JC, Muderspach LI, Schlaerth JB, Morrow CP. The role of endocervical curettage at cervical conization for high-grade dysplasia. Obstet Gynecol 1995;85:197-201.
91. Nuovo J, Melnikow J, Willan AR, Chan BK. Treatment outcomes for squamous intraepithelial lesions. Int J Gynaecol Obstet 2000;68:25-33.
92. Tidbury P, Singer A, Jenkins D. CIN 3: The role of lesion size in invasion. Br J Obstet Gynaecol 1992;99:583-6.
93. Andersen ES, Nielsen K, Pedersen B. The reliability of preconization diagnostic evaluation in patients with cervical intraepithelial neoplasia and microinvasive carcinoma. Gynecol Oncol 1995;59:143-7.
94. Burke L, Covell L, Antonioli D. Carbon dioxide laser therapy of cervical intraepithelial neoplasia: Factors determining success rate. Lasers Surg Med 1980;1:113-22.
95. Duggan BD, Felix JC, Muderspach LI, et al. Cold-knife conization versus conization by the loop electrosurgical excision procedure: A randomized, prospective study. Am J Obstet Gynecol 1999;180:276-82.
96. Naumann RW, Bell MC, Alvarez RD, et al. LLETZ is an acceptable alternative to diagnostic cold-knife conization. Gynecol Oncol 1994;55:224-8.
97. Economos K, Perez Veridiano N, Delke I, Collado ML, Tancer ML. Abnormal cervical cytology in pregnancy: A 17-year experience. Obstet Gynecol 1993;81:915-8.
98. Connor JP. Noninvasive cervical cancer complicating pregnancy. Obstet Gynecol Clin North Am 1998;25:331-42.
99. Robinson WR, Webb S, Tirpack J, Degefu S, O'Quinn AG. Management of cervical intraepithelial neoplasia during pregnancy with LOOP excision. Gynecol Oncol 1997;64:153-5.
100. Yost NP, Santoso JT, McIntire DD, Iliya FA. Postpartum regression rates of antepartum cervical intraepithelial neoplasia II and III lesions. Obstet Gynecol 1999;93:359-62.
101. Wright TC, Ellerbock TV, Chiasson MA, Van De Vanter N, Sun XW. Cervical intraepithelial neoplasia in women infected with human immunodeficiency virus: Prevalence, risk factors, and validity of Papanicolaou smears. New York Cervical Disease Study. Obstet Gynecol 1994;84:591-7.
102. Sun XW, Kuhn L, Ellerbrock TV, Chiasson MA, Bush TJ, Wright Jr TC. Human papillomavirus infection in women infected with the human immunodeficiency virus. N Engl J Med 1997;337:1343-9.
103. Palefsky JM, Minkoff H, Kalish LA, et al. Cervicovaginal human papillomavirus infection in human immunodeficiency virus-1 (HIV)-positive and high-risk HIV-negative women. J Natl Cancer Inst 1999;91:226-36.
104. Holcomb K, Matthews RP, Chapman JE, et al. The efficacy of cervical conization in the treatment of cervical intraepithelial neoplasia in HIV-positive women. Gynecol Oncol 1999;74:428-31.
105. Ellerbrock TV, Chiasson MA, Bush TJ, Sun XW, Sawo D, Brudney K, et al. Incidence of cervical squamous intraepithelial lesions in HIV-infected women. JAMA 2000;283:1031-7.
106. Massad LS, Ahdieh L, Benning L, Minkoff H, Greenblatt RM, Watts H, et al. Evolution of cervical abnormalities among women with HIV-1: Evidence from surveillance cytology in the women's interagency HIV study. J Acquir Immune Defic Syndr 2001;27:432-42.
107. Tate DR, Anderson RJ. Recurrence of cervical dysplasia in the human immunodeficiency virusseropositive paitent. Obstet Gynecol 2001;97(Suppl 1):S60.
108. Maiman M, Watts DH, Anderson J, et al. Vaginal 5-fluorouracil for high-grade cervical dysplasia in human immunodeficiency virus infection: A randomized trial. Obstet Gynecol 1999;94:954-61.
109. Reich O, Pickel H, Lahousen M, Tamussino K, Winter R. Cervical intraepithelial neoplasia III: Long-term outcome after cold-knife conization with clear margins. Obstet Gynecol 2001;97:428-30.
110. Reich O, Lahousen M, Pickel H, Tamussino K, Winter R. Cervical intraepithelial neoplasia III: Long-term follow-up after cold-knife conization with involved margins. Obstet Gynecol 2002;99:193-6.
111. Soutter WP, de Barros Lopes A, Fletcher A, Monaghan JM, Duncan ID, Paraskevaidis E, et al. Invasive cervical cancer after conservative therapy for cervical intraepithelial neoplasia. Lancet 1997;349:978-80.
112. Kolstad P, Klem V. Long-term followup of 1121 cases of carcinoma in situ. Obstet Gynecol 1976;48:125-9.
113. Anderson MC. Invasive carcinoma of the cervix following local destructive treatment for cervical intraepithelial neoplasia. Br J Obstet Gynaecol 1993;100:657-63.
114. Brown JV, Peters WA, Corwin DJ. Invasive carcinoma after cone biopsy for cervical intraepithelial neoplasia. Gynecol Oncol 1991;40:25-8.
115. Gornall RJ, Boyd IE, Manolitsas T, Herbert A. Interval cervical cancer following treatment for cervical intraepithelial neoplasia. Int J Gynecol Cancer 2000;10:198-202.
116. Flannelly G, Bolger B, Fawzi H, De Lopes AB, Monaghan JM. Follow up after LLETZ: Could schedules be modified according to risk of recurrence? BJOG 2001;108:1025-30.
117. Gardeil F, Barry-Walsh C, Prendiville W, Clinch J, Turner MJ. Persistent intraepithelial neoplasia after excision for cervical intraepithelial neoplasia grade III. Obstet Gynecol 1997;89:419-22.
118. Giacalone PL, Laffargue F, Aligier N, Roger P, Combecal J, Daures JP. Randomized study comparing two techniques of conization: Cold knife versus loop excision. Gynecol Oncol 1999;75:356-60.
119. Chan KS, Yu KM, Lok YH, Sin SY, Tang LC. Conservative management of patients with histological incomplete excision of cervical intraepithelial neoplasia after large loop excision of transformation zone. Chin Med J (Engl) 1997;110:617-9.
120. Narducci F, Occelli B, Boman F, Vinatier D, Leroy JL. Positive margins after conization and risk of persistent lesion. Gynecol Oncol 2000;76:311-4
121. Felix JC, Muderspach LI, Duggan BD, Roman LD. The significance of positive margins in loop electrosurgical cone biopsies. Obstet Gynecol 1994;84:996-1000.
122. Zaitoun AM, McKee G, Coppen MJ, Thomas SM, Wilson PO. Completeness of excision and follow up cytology in patients treated with loop excision biopsy. J Clin Pathol 2000;53:191-6.
123. Murdoch JB, Morgan PR, Lopes A, Monaghan JM. Histological incomplete excision of CIN after large loop excision of the transformation zone (LLETZ) merits careful follow up, not retreatment. Br J Obstet Gynaecol 1992;99:990-3.
124. Lapaquette TK, Dinh TV, Hannigan EV, Doherty MG, Yandell RB, Buchanan VS. Management of patients with positive margins after cervical conization. Obstet Gynecol 1993;82:440-3.
125. Paraskevaidis E, Lolis ED, Koliopoulos G, Alamanos Y, Fotiou S, Kitchener HC. Cervical intraepithelial neoplasia outcomes after large loop excision with clear margins. Obstet Gynecol 2000;95:828-31.
126. Bar-Am A, Daniel Y, Ron IG, Niv J, Kupferminc MJ, Bornstein J, Lessing JB. Combined colposcopy, loop conization, and laser vaporization reduces recurrent abnormal cytology and residual disease in cervical dysplasia. Gynecol Oncol 2000;78:47-51.
127. Lopes A, Mor-Yosef S, Pearson S, Ireland D, Monaghan JM. Is routine colposcopic assessment necessary following laser ablation of cervical intraepithelial neoplasia? Br J Obstet Gynaecol 1990;97:175-7.
128. Paraskevaidis E, Koliopoulos G, Alamanos Y, Malamou-Mitsi V, Lolis ED, Kitchener HC. Human papillomavirus testing and the outcome of treatment for cervical intraepithelial neoplasia. Obstet Gynecol 2001;98:833-6.
129. Strand A, Wilander E, Zehbe I, Rylander E. High risk HPV persists after treatment of genital papillomavirus infection but not after treatment of cervical intraepithelial neoplasia. Acta Obstet Gynecol Scand 1997;76:140-4.
130. Jain S, Tseng CJ, Horng SG, Soong YK, Pao CC. Negative predictive value of human papillomavirus test following conization of the cervix uteri. Gynecol Oncol 2001;82:177-80.
131. Lin CT, Tseng CJ, Lai CH, et al. Value of human papillomavirus deoxyribonucleic acid testing after conization in the prediction of residual disease in the subsequent hysterectomy specimen. Am J Obstet Gynecol 2001;184:940-5.
132. Kucera E, Sliutz G, Czerwenka K, Breitenecker G, Leodolter S, Reinthaller A. Is high-risk human papillomavirus infection associated with cervical intraepithelial neoplasia eliminated after conization by large-loop excision of the transformation zone? Eur J Obstet Gynecol Reprod Biol 2001;100:72-6.
133. Kjellberg L, Wadell G, Bergman F, Isaksson M, Angstrom T, Dillner J. Regular disappearance of the human papillomavirus genome after conization of cervical dysplasia by carbon dioxide laser. Am J Obstet Gynecol 2000;183:1238-42.
134. Cruickshank ME, Sharp L, Chambers G, Smart L, Murray G. Persistent infection with human papillomavirus following the successful treatment of high grade cervical intraepithelial neoplasia. BJOG 2002;109:579-81.