Involvement of CD44 in leukocyte trafficking at the blood-retinal barrier

Journal of Leukocyte Biology

Volumn 72, Issue 6, 2002, Pages 1133-1141

  Xu, Heping ^a   Manivannan, Ayyakkannu ^a   Liversidge, Janet ^a   Sharp, Peter F ^a   Forrester, John V ^a   Crane, Isabel J ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Adhesion molecule; Apoptosis; Experimental autoimmune uveoretinitis; Hyaluronic acid; Inflammation

Indexed keywords

CALCEIN; HERMES ANTIGEN; HYALURONIC ACID; HYALURONIDASE; LIGAND; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY IM7; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; BLOOD RETINA BARRIER; CELL INFILTRATION; CELL INTERACTION; CELL TRANSFER; CELL TRANSPORT; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; IMMUNOLOCALIZATION; LEUKOCYTE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETINA VEIN; SPLEEN CELL; UVEORETINITIS; VENULE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD44; AUTOIMMUNE DISEASES; BLOOD-RETINAL BARRIER; CHEMOTAXIS, LEUKOCYTE; ENDOTHELIUM, VASCULAR; FEMALE; LEUKOCYTE ROLLING; MICE; MICE, INBRED STRAINS; RETINAL VESSELS; RETINITIS; UVEITIS;

ANIMALIA;

EID: 0036914241     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Springer, T. A. (1994) Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell 76, 301-314.
2. Siegelman, M. H., DeGrendele, H. C., Estess, P. (1999) Activation and interaction of CD44 and hyaluronan in immunological systems. J. Leukoc. Biol. 66, 315-321.
3. DeGrendele, H. C., Estess, P., Siegelman, M. H. (1997) Requirement for CD44 in activated T cell extravasation into an inflammatory site. Science 278, 672-675.
4. Estess, P., DeGrendele, H. C., Pascual, V., Siegelman, M. H. (1998) Functional activation of lymphocyte CD44 in peripheral blood is a marker of autoimmune disease activity. J. Clin. Invest. 102, 1173-1182.
5. Pure, E., Cuff, C. A. (2001) A crucial role for CD44 in inflammation. Trends Mol. Med. 7, 213-221.
6. Culty, M., Miyake, K., Kincade, P. W., Sikorski, E., Butcher, E. C., Underhill, C., Silorski, E. (1990) The hyaluronate receptor is a member of the CD44 (H-CAM) family of cell surface glycoproteins. J. Cell Biol. 111, 2765-2774.
7. Zoller, M. (1995) CD44: Physiological expression of distinct isoforms as evidence for organ-specific metastasis formation. J. Mol. Med. 73, 425-438.
8. Borland, G., Ross, J. A., Guy, K. (1998) Forms and functions of CD44. Immunology 93, 139-148.
9. Bourrguignon, L. Y., Iida, N., Welsh, C. F., Zhu, D., Krongrad, A., Pasquale, D. (1995) Involvement of CD44 and its variant isoforms in membrane-cytoskeleton interaction, cell adhesion and tumor metastasis. J. Neurooncol. 26, 201-208.
10. Jones, M., Tussey, L., Athanasou, N., Jackson, D. G. (2000) Heparan sulfate proteoglycan isoforms of the CD44 hyaluronan receptor induced in human inflammatory macrophages can function as paracrine regulators of fibroblast growth factor action. J. Biol. Chem. 275, 7964-7974.
11. Nedvetzki, S., Walmsley, M., Alpert, E., Williams, R. O., Feldmann, M., Naor, D. (1999) CD44 involvement in experimental collagen-induced arthritis (CIA). J. Autoimmun. 13, 39-47.
12. Mikecz, K., Brennan, F. R., Kim, J. H., Glant, T. T. (1995) Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis. Nat. Med. 1, 558-563.
13. Verdrengh, M., Holmdahl, R., Tarkowski, A. (1995) Administration of antibodies to hyaluronanreceptor (CD44) delays the start and ameliorates the severity of collagen II arthritis. Scand. J. Immunol. 42, 353-358.
14. Brocke, S., Piercy, C., Steinman, L., Weissman, I. L., Veromaa, T. (1999) Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment. Proc. Natl. Acad. Sci. USA 96, 6896-6901.
15. Brennan, F. R., O'Neill, J. K., Allen, S. J., Butter, C., Nuki, G., Baker, D. (1999) CD44 is involved in selective leucocyte extravasation during inflammatory central nervous system disease. Immunology 98, 427-435.
16. Weiss, L., Slavin, S., Reich, S., Cohen, P., Shuster, S., Stern, R., Kaganovsky, E., Okon, E., Rubinstein, A. M., Naor, D. (2000) Induction of resistance to diabetes in non-obese diabetic mice by targeting CD44 with a specific monoclonal antibody. Proc. Natl. Acad. Sci. USA 97, 285-290.
17. Caspi, R. R., Chan, C. C., Wiggert, B., Chader, G. J. (1990) The mouse as a model of experimental autoimmune uveoretinitis (EAU). Curr. Eye Res. 9 (Suppl.), 169-174.
18. Forrester, J. V., Liversidge, J., Dua, H. S., Dick, A., Harper, F., Mc-Menamin, P. G. (1992) Experimental autoimmune uveoretinitis: A model system for immunointervention: A review. Curr. Eye Res, 11 (Suppl), 33-40.
19. Xu, H. P., Manivannan, A., Daniels, G., Liversidge, J., Sharp, P. F., Forrester, J. V., Crane, I. J. (2001) Evaluation of leukocyte dynamics in mouse retinal circulation with scanning laser ophthalmoscopy (video report). Br. J. Ophthalmol. Available at: 〉http://bjo.bmjjournals.com/misc/eyemov.shtml〈.
20. Xu, H. P., Manivannan, A., Goatman, K. A., Liversidge, J., Sharp, P. F., Forrester, J. V., Crane, I. J. (2002) Improved leukocyte tracking in mouse retinal and choroidal circulation. Exp. Eye Res. 74, 403-410.
21. Silver, P. B., Chan, C. C., Wiggert, B., Caspi, R. R. (1999) The requirement for pertussis to induce EAU is strain-dependent: B10.RIII, but not B10.A mice, develop EAU and Th1 responses to IRBP without pertussis treatment. Invest. Ophthalmol. Vis. Sci. 40, 2898-2905.
22. Jiang, H. R., Wei, X., Niedbala, W., Lumsden, L., Liew, F. Y., Forrester, J. V. (2001) IL-18 not required for IRBP peptide-induced EAU: Studies in gene-deficient mice. Invest. Ophthalmol. Vis. Sci. 42, 177-182.
23. Caspi, R. R. (1994) Experimental autoimmune uveoretinitis-rat and mouse. In Autoimmune Disease Models: A Guidebook (I. Cohen, A. Miller, eds.), San Diego, CA, Academic, 57-81.
24. Dick, A. D., Cheng, Y. F., Liversidge, J., Forrester, J. V. (1994) Intranasal administration of retinal antigens suppresses retinal antigen-induced experimental autoimmune uveoretinitis. Immunology 82, 625-631.
25. Abbitt, K. B., Rainger, G. E., Nash, G. B. (2000) Effects of fluorescent dyes on selectin and integrin-mediated stages of adhesion and migration of flowing leukocytes. J. Immunol. Methods 239, 109-119.
26. Hua, Q., Knudson, C. B., Knudson, W. (1993) Internalization of hyaluronan by chondrocytes occurs via receptor-mediated endocytosis. J. Cell Sci. 106, 365-375.
27. Parish, N. M., Brennan, F. R., Cooke, A. (1999) Anti-CD44 treatment does not prevent the extravasation of autopathogenic T cells to the thyroid in experimental autoimmune thyroiditis. Immunology 97, 533-539.
28. Chan-Ling, T. (1997) Glial, vascular, and neuronal cytogenesis in whole-mounted cat retina. Microsc. Res. Tech. 36, 1-16.
29. Vermes, I., Haanen, C., Steffens-Nakken, H., Reutelingsperger, C. (1995) A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J. Immunol. Methods 184, 39-51.
30. Mikecz, K., Dennis, K., Shi, M., Kim, J. H. (1999) Modulation of hyaluronan receptor (CD44) function in vivo in a murine model of rheumatoid arthritis. Arthritis Rheum. 42, 659-668.
31. Asari, A., Miyauchi, S., Takahashi, T., Kohno, K., Uchiyama, Y. (1992) Localization of hyaluronic acid, chondroitin sulfate, and CD44 in rabbit cornea. Arch. Histol. Cytol. 55, 503-511.
32. Asari, A., Morita, M., Sekiguchi, T., Okamura, K., Horie, K., Miyauchi, S. (1996) Hyaluronan, CD44 and fibronectin in rabbit corneal epithelial wound healing. Jpn. J. Ophthalmol. 40, 18-25.
33. Kuppner, M. C., Liversidge, J., McKillop-Smith, S., Lumsden, L., Forrester, J. V. (1993) Adhesion molecule expression in acute and fibrotic sympathetic ophthalmia. Curr. Eye Res. 12, 923-934.
34. Nandi, A., Estess, P., Siegelman, M. H. (2000) Hyaluronan anchoring and regulation on the surface of vascular endothelial cells is mediated through the functionally active form of CD44. J. Biol. Chem. 275, 14939-14948.
35. DeGrendele, H. C., Estess, P., Picker, L. J., Siegelman, M. H. (1996) CD44 and its ligand hyaluronate mediate rolling under physiologic flow: A novel lymphocyte-endothelial cell primary adhesion pathway. J. Exp. Med. 183, 1119-1130.
36. Foger, N., Marhaba, R., Zoller, M. (2000) CD44 supports T cell proliferation and apoptosis by apposition of protein kinases. Eur. J. Immunol. 30, 2888-2899.
37. Sugiyama, K., Komada, Y., Deguchi, T., Zhang, X. L., Azuma, E., Ido, M., Yamamoto, H., Sakurai, M. (1999) CD3-mediated T cell activation is inhibited by anti-CD44 monoclonal antibodies directed to the hyaluronan-binding region. Immunol. Invest. 28, 185-200.
38. Shimizu, Y., Van Seventer, G. A., Siraganian, R., Wahl, L., Shaw, S. (1989) Dual role of the CD44 molecule in T cell adhesion and activation. J. Immunol. 143, 2457-2463.