Upregulation of fatty acid synthase gene expression in experimental chronic renal failure

Metabolism: Clinical and Experimental

Volumn 51, Issue 12, 2002, Pages 1605-1610

  Szolkiewicz, Marek ^a   Nieweglowski, Tomasz ^a   Korczynska, Justyna ^a   Sucajtys, Elzbieta ^a   Stelmanska, Ewa ^a   Goyke, Elzbieta ^a   Swierczynski, Julian ^a   Rutkowski, Boleslaw ^a  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; CYTOKINE; FATTY ACID SYNTHASE; INSULIN; LIPID; LIPOPROTEIN; LIPOPROTEIN LIPASE; LIVER TRIACYLGLYCEROL LIPASE; MESSENGER RNA; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ALCOHOL PRODUCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC KIDNEY FAILURE; CLEARANCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVITY; ENZYME MECHANISM; EPIDIDYMIS FAT; GENE EXPRESSION REGULATION; HYPERTRIGLYCERIDEMIA; HYPOTHESIS; INSULIN BLOOD LEVEL; LIPID METABOLISM; LIPOGENESIS; LIPOPROTEIN BLOOD LEVEL; LIVER; MALE; NEPHRECTOMY; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; RAT STRAIN; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION; WESTERN BLOTTING;

EID: 0036912310     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1053/meta.2002.36302     Document Type: Article

References (36)

1. Lacour B, Drueke T: Lipid metabolism, in Massry SG, Glassok, RC (eds): Textbook of Nephrology. Baltimore, MD, Williams & Wilkins, 1995, pp 1395-1404
2. Bagdade JD, Porte D, Bierman EL: Hypertriglicerydemia: A metabolic consequence of chronic renal failure. N Engl J Med 279: 181-185, 1968
3. Grundy SM: Management of hyperlipidemia of kidney disease. Kidney Int 37:847-853, 1990
4. Wanner C, Frommherz K, Horl WH: Hyperlipoproteinemia in chronic renal failure: Pathophysiological and therapeutic aspects. Cardiology 78:202-217, 1991
5. Attman PO: Hyperlipoproteinemia in renal failure: Pathogenesis and perspectives for intervention. Nephrol Dial Transplant 8:294-295, 1993
6. Massay ZA, Jungers P, Roullet JB, et al: Disturbances of apolipoprotein distribution in lipoproteins of uremic patients. J Nephrol 6:153-158, 1993
7. Attman PO, Samuelsson O, Alaupovic P: Lipoprotein metabolism and renal failure. Am J Kidney Dis 21:573-592, 1993
8. Chan MK, Persaud J, Varghese Z, et al: Pathogenetic roles of post-heparin lipases in lipid abnormalities in hemodialysis patients. Kidney Int 25:812-818, 1984
9. Vaziri ND, Liang K: Down-regulation of VLDL receptor expression in chronic experimental renal failure. Kidney Int 51:913-919, 1997
10. Liang K, Vaziri ND: Acquired VLDL receptor deficiency in experimental nephrosis. Kidney Int 51:1761-1765, 1997
11. Arnadottir M: Pathogenesis of dyslipoproteinemia in renal insufficiency: The role of lipoprotein lipase and hepatic lipase Scand J Clin Lab Invest 57:1-11, 1997
12. Vaziri ND, Liang K: Down-regulation of tissue lipoprotein lipase expression in experimental chronic renal failure. Kidney Int 50:1928-1935, 1996
13. Cheung AK, Parker ChJ, Ren K, et al: Increase lipase inhibition in uremia: Identification of pre-β-HDL as a major inhibitor in normal and uremic plasma Kidney Int 49:1360-1371, 1996
14. Liang K, Vaziri ND: Down-regulation of hepatic lipase expression in experimental nephrotic syndrome Kidney Int 51:1933-1937, 1997
15. Arnadottir M, Thysell H, Dallongeville J, et al: Evidence that reduced lipoprotein lipase activity is not a primary pathogenetic factor for hypertriglyceridemia in renal failure. Kidney Int 48:779-784, 1995
16. Chan MK, Varghese Z, Persaud JW, et al: Hyperlipidemia in patients on maintenance hemo- and peritoneal dialysis: The relative pathogenetic roles of triglyceride production and triglyceride removal. Clin Nephrol 17:183-190, 1982
17. Girard J, Ferre O, Foufelle F: Mechanisms by which carbohydrate regulate expression of genes for glycolytic and lipogenic enzymes. Annu Rev Nutr 17:325-352, 1997
18. Maack T, Johnson V, Kau ST, et al: Renal filtration, transport, and metabolism of low-molecular-weight proteins: A review. Kidney Int 16:251-270, 1979
19. Feingold KR, Soued M, Serio MK, et al: The effect of diet on tumor necrosis factor stimulation of hepatic lipogenesis. Metabolism 39:623-632, 1990
20. Grunfeld C, Dinarello CA, Feingold KR: Tumor necrosis factor-alpha, interleukin-1 and interferon alpha stimulate triglyceride synthesis in HepG2 cells. Metabolism 40:894-898, 1991
21. Guarnieri G, Toigo G, Fiotti N, et al. Mechanisms of malnutrition in uremia. Kidney Int 52:S41-S44, 1997 (suppl 62)
22. Bagdade JD, Yee E, Wilson DE, et al: Hyperlipidemia in renal failure: Studies of plasma lipoproteins, hepatic trigliceride production, and tissue lipoprotein lipase in a chronically uremic rat model. J Lab Clin Med 91:176-186, 1978
23. Heuck CC, Liersch M, Ritz E, et al: Hyperlipoproteinemia in experimental chronic renal insufficiency in the rat. Kidney Int 14:142-150, 1978
24. Swierczynski J, Korczynska J, Szolkiewicz M, et al: Low leptin mRNA level in adipose tissue and normoleptinemia in experimental chronic renal failure. Exp Nephrol 9:54-59, 2001
25. Kochan Z, Karbowska J, Swierczynski J: Unusual increase of lipogenesis in rat white adipose tissue after multiple cycles of starvation-refeeding. Metabolism 46:10-17, 1997
26. Karbowska J, Kochan Z, Zelewski L, et al: Tissue specific effect of clofibrate on rat lipogenic enzyme gene expression. Eur J Pharmacol 370:329-336, 1999
27. Trayhurn P, Duncan JS, Rayner DV: Acute cold-induced suppression of ob (obese) gene expression in white adipose tissue of mice: Mediation by the sympathetic system. Biochem J 311:729-733, 1995
28. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159, 1987
29. Kochan Z, Karbowska J, Swierczynski J: Effect of clofibrate on malic enzyme and leptin mRNA levels in rat brown and white adipose tissue Horm Metab Res 31:538-542, 1999
30. Zelewski M, Swierczynski J: Comparative studies on lipogenic enzyme activities in brown adipose tissue and liver of rat during starvation-refeeding transition and cold exposure. Comp Biochem Physiol 97B:59-63, 1990
31. Stansbie D, Brownsey RW, Crettaz M, et al: Acute effect in vivo of anti-insulin serum on rates of fatty acid synthesis and activities of acetyl-coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose tissue of fed rats. Biochem J 160:413-416, 1976
32. Verschoor L, Lammers R, Birkenhager JC: Triglyceride turnover in severe chronic non-nephrotic renal failure. Metabolism 27:879-883, 1978
33. Kochan Z, Goyke E, Karbowska J, Slominska E, Swierczynski J: The decrease of rat postprandial plasma triacylglycerol concentration after multiple cycles of starvation refeeding. Horm Metab Res 33:26-29, 2001
34. Jokinen EV, Landschulz KT, Wyne KL, et al: Regulation of the very low density lipoprotein receptor by thyroid hormone in rat skeletal muscle. J Biol Chem 269:26411-26418, 1994
35. Nogalska A, Swierczynski J: The age-related differences in obese and fatty acids synthase gene expression in white adipose tissue of rat. Biochim Biophys Acta 1533:73-80, 2001
36. Hasty AH, Shimano H, Osuga Ji J, et al: Severe hypercholesterolemia, hypertriglicerydemia and atherosclerosis in mice lacking both leptin and the low density lipoprotein receptor. J Biol Chem 276:37402-37408, 2001