메뉴 건너뛰기




Volumn 370, Issue 3, 1999, Pages 329-336

Tissue-specific effect of clofibrate on rat lipogenic enzyme gene expression

Author keywords

Brown adipose tissue; Clofibrate; Fatty acid synthase; Lipogenesis; Liver; Malic enzyme; mRNA; Rat; White adipose tissue

Indexed keywords

CLOFIBRATE; FATTY ACID SYNTHASE; MALATE DEHYDROGENASE (DECARBOXYLATING); MESSENGER RNA;

EID: 0032963678     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00129-6     Document Type: Article
Times cited : (29)

References (41)
  • 1
    • 0015158730 scopus 로고
    • Inhibition of hepatic triglyceride formation by clofibrate
    • Adams L.L., Webb W.W., Fallon H.J. Inhibition of hepatic triglyceride formation by clofibrate. J. Clin. Invest. 50:1971;2339-2346.
    • (1971) J. Clin. Invest. , vol.50 , pp. 2339-2346
    • Adams, L.L.1    Webb, W.W.2    Fallon, H.J.3
  • 3
    • 0019158343 scopus 로고
    • Disposition of clofibrate in the rat. Acute and chronic administration
    • Baldwin J.R., Witiak D.T., Feller D.R. Disposition of clofibrate in the rat. Acute and chronic administration. Biochem. Pharmacol. 29:1980;3143-3154.
    • (1980) Biochem. Pharmacol. , vol.29 , pp. 3143-3154
    • Baldwin, J.R.1    Witiak, D.T.2    Feller, D.R.3
  • 4
    • 0026577370 scopus 로고
    • Tissue-specific regulation of fatty acid synthesis by thyroid hormone
    • Blennemann B., Moon Y.K., Freake H.C. Tissue-specific regulation of fatty acid synthesis by thyroid hormone. Endocrinology. 130:1992;637-643.
    • (1992) Endocrinology , vol.130 , pp. 637-643
    • Blennemann, B.1    Moon, Y.K.2    Freake, H.C.3
  • 8
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 9
    • 84916721870 scopus 로고
    • Stimulation of hepatic synthesis of fatty acids by clofibrate and by a tetralin phenoxy isobutyric acid
    • Suppl.
    • Duncan C.H., Best M.M. Stimulation of hepatic synthesis of fatty acids by clofibrate and by a tetralin phenoxy isobutyric acid. Circulation. 39-40(III):1969;6. Suppl.
    • (1969) Circulation , vol.3940 , Issue.III , pp. 6
    • Duncan, C.H.1    Best, M.M.2
  • 10
    • 0015154668 scopus 로고
    • Effects of p-chlorophenoxyisobutyric acid (CPIB) on adipose tissue triglycerides synthesis, lipogenesis, and some related enzymes
    • Giocoli G., Tepperman H.M., Tepperman J. Effects of p-chlorophenoxyisobutyric acid (CPIB) on adipose tissue triglycerides synthesis, lipogenesis, and some related enzymes. Proc. Soc. Biol. Med. 138:1971;512-516.
    • (1971) Proc. Soc. Biol. Med. , vol.138 , pp. 512-516
    • Giocoli, G.1    Tepperman, H.M.2    Tepperman, J.3
  • 11
    • 0020533327 scopus 로고
    • Effects of clofibrate, bezafibrate, fenofibrate and probucol on plasma lipolytic enzymes in normolipidaemic subjects
    • Heller F., Harvengt C. Effects of clofibrate, bezafibrate, fenofibrate and probucol on plasma lipolytic enzymes in normolipidaemic subjects. Eur. J. Pharmacol. 25:1983;57-63.
    • (1983) Eur. J. Pharmacol. , vol.25 , pp. 57-63
    • Heller, F.1    Harvengt, C.2
  • 12
    • 0029839416 scopus 로고    scopus 로고
    • Thyromimetic mode of action of peroxisome proliferators: Activation of 'malic' enzyme gene transcription
    • Hertz R., Nikodem V., Ben-Ishai A., Berman I., Bar-Tana J. Thyromimetic mode of action of peroxisome proliferators: activation of 'malic' enzyme gene transcription. Biochem. J. 319:1996;241-248.
    • (1996) Biochem. J. , vol.319 , pp. 241-248
    • Hertz, R.1    Nikodem, V.2    Ben-Ishai, A.3    Berman, I.4    Bar-Tana, J.5
  • 13
    • 0030818756 scopus 로고    scopus 로고
    • Polarity and specific sequence requirements of peroxisome proliferator-activated receptor (PPAR)/retinoid X receptor heterodimer binding to DNA
    • IJpenberg A., Jeannin E., Wahli W., Desvergne B. Polarity and specific sequence requirements of peroxisome proliferator-activated receptor (PPAR)/retinoid X receptor heterodimer binding to DNA. J. Biol. Chem. 272:1997;20108-20117.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20108-20117
    • Ijpenberg, A.1    Jeannin, E.2    Wahli, W.3    Desvergne, B.4
  • 14
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann I., Green S. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature. 347:1990;645-650.
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 15
    • 0026594937 scopus 로고
    • Development changes of lipogenic enzyme activities and lipogenesis in brown adipose tissue and liver of the rat
    • Kochan Z., Swierczynski J. Development changes of lipogenic enzyme activities and lipogenesis in brown adipose tissue and liver of the rat. Comp. Biochem. Physiol. 101B:1992;283-288.
    • (1992) Comp. Biochem. Physiol. , vol.101 , pp. 283-288
    • Kochan, Z.1    Swierczynski, J.2
  • 16
    • 0027381667 scopus 로고
    • Inhibition of lipogenesis in rat brown adipose tissue by clofibrate
    • Kochan Z., Bukato G., Swierczynski J. Inhibition of lipogenesis in rat brown adipose tissue by clofibrate. Biochem. Pharmacol. 46:1993;1501-1506.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 1501-1506
    • Kochan, Z.1    Bukato, G.2    Swierczynski, J.3
  • 17
    • 0018662384 scopus 로고
    • The immediate and long-term effects of clofibrate on the metabolism of the perfused rat liver
    • Laker M.E., Mayes P.A. The immediate and long-term effects of clofibrate on the metabolism of the perfused rat liver. Biochem. Pharmacol. 28:1979;2813-2827.
    • (1979) Biochem. Pharmacol. , vol.28 , pp. 2813-2827
    • Laker, M.E.1    Mayes, P.A.2
  • 18
    • 0015522471 scopus 로고
    • Inhibition of monoacylglycerolphosphate formation by chlorophenoxyisobutyrate and β-benzalbutyrate
    • Lamb R.G., Fallon H.J. Inhibition of monoacylglycerolphosphate formation by chlorophenoxyisobutyrate and β-benzalbutyrate. J. Biol. Chem. 247:1972;1281-1287.
    • (1972) J. Biol. Chem. , vol.247 , pp. 1281-1287
    • Lamb, R.G.1    Fallon, H.J.2
  • 19
    • 0008910860 scopus 로고
    • Disorders of lipid transport
    • In: Weatheral, D.J., Ledingham, J.G.G., Warrel, D.A. (Eds.), Oxford Univ. Press, Oxford
    • Lewis, B., 1983. Disorders of lipid transport. In: Weatheral, D.J., Ledingham, J.G.G., Warrel, D.A. (Eds.), Oxford Textbook of Medicine. Oxford Univ. Press, Oxford, pp. 985-970.
    • (1983) Oxford Textbook of Medicine , pp. 985-970
    • Lewis, B.1
  • 21
    • 0014690931 scopus 로고
    • Inhibition of hepatic acetyl-CoA carboxylase by hypolipidaemic agents
    • Maragoudakis M.E. Inhibition of hepatic acetyl-CoA carboxylase by hypolipidaemic agents. J. Biol. Chem. 244:1969;5005-5013.
    • (1969) J. Biol. Chem. , vol.244 , pp. 5005-5013
    • Maragoudakis, M.E.1
  • 22
    • 0020040371 scopus 로고
    • Bezafibrate and clofibrate: Effects on plasma lipids, lipoproteins and apoproteins compared in familial hypercholesterolemia
    • Martini S., Valerio G., Fellin R., Baggio G., Gasparotto A., Baiocchi M.R., Baldo G., Crepaldi G. Bezafibrate and clofibrate: effects on plasma lipids, lipoproteins and apoproteins compared in familial hypercholesterolemia. Curr. Ther. Res. 31:1982;354-361.
    • (1982) Curr. Ther. Res. , vol.31 , pp. 354-361
    • Martini, S.1    Valerio, G.2    Fellin, R.3    Baggio, G.4    Gasparotto, A.5    Baiocchi, M.R.6    Baldo, G.7    Crepaldi, G.8
  • 23
    • 0020517239 scopus 로고
    • Some comparative effects of gemfibrozil, clofibrate, bezafibrate, cholestyramine and compactin on sterol metabolism in rats
    • Maxwell R.E., Nawrocki J.W., Uhlendorf P.D. Some comparative effects of gemfibrozil, clofibrate, bezafibrate, cholestyramine and compactin on sterol metabolism in rats. Atherosclerosis. 48:1983;195-203.
    • (1983) Atherosclerosis , vol.48 , pp. 195-203
    • Maxwell, R.E.1    Nawrocki, J.W.2    Uhlendorf, P.D.3
  • 24
    • 0023688411 scopus 로고
    • The influence of starvation and natural refeeding on the rate of triacylglycerol/fatty acid substrate cycling in brown adipose tissue and different white adipose site of the rat in vivo. The role of insulin and the sympathetic nervous system
    • Mercer S.W., Williamson D.H. The influence of starvation and natural refeeding on the rate of triacylglycerol/fatty acid substrate cycling in brown adipose tissue and different white adipose site of the rat in vivo. The role of insulin and the sympathetic nervous system. Biosci. Rep. 8:1988;147-153.
    • (1988) Biosci. Rep. , vol.8 , pp. 147-153
    • Mercer, S.W.1    Williamson, D.H.2
  • 25
    • 0014088546 scopus 로고
    • The mechanism underlying the hypolipidaemic effects of Atromid S, nicotinic acid and benzmolecene-I
    • Mishkel M.A., Webb W.F. The mechanism underlying the hypolipidaemic effects of Atromid S, nicotinic acid and benzmolecene-I. Biochem. Pharmacol. 16:1967;897-905.
    • (1967) Biochem. Pharmacol. , vol.16 , pp. 897-905
    • Mishkel, M.A.1    Webb, W.F.2
  • 26
    • 0016785105 scopus 로고
    • Effects of ethyl p-chlorophenoxyisobutyrate on carbohydrate and fatty acid metabolism in rat liver
    • Miyazawa S., Sakurai T., Imura M., Hashimoto T. Effects of ethyl p-chlorophenoxyisobutyrate on carbohydrate and fatty acid metabolism in rat liver. J. Biochem. 78:1975;1171-1176.
    • (1975) J. Biochem. , vol.78 , pp. 1171-1176
    • Miyazawa, S.1    Sakurai, T.2    Imura, M.3    Hashimoto, T.4
  • 28
    • 0013926856 scopus 로고
    • Changes in the liver concentrations of the nicotinamide adenine dinucleotide coenzymes and in the activities of oxidoreductase enzymes following treatment of the rat with ethyl chlorophenoxyisobutyrate (Atromid S)
    • Platt D.S., Cockrill B.L. Changes in the liver concentrations of the nicotinamide adenine dinucleotide coenzymes and in the activities of oxidoreductase enzymes following treatment of the rat with ethyl chlorophenoxyisobutyrate (Atromid S). Biochem. Pharmacol. 15:1966;927-935.
    • (1966) Biochem. Pharmacol. , vol.15 , pp. 927-935
    • Platt, D.S.1    Cockrill, B.L.2
  • 29
    • 0030783119 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid suppression of hepatic fatty acid synthase and S14 gene expression does not require peroxisome proliferator-activated receptor α
    • Ren B., Thelen A.P., Peters J.M., Gonzales F.J., Jump D.B. Polyunsaturated fatty acid suppression of hepatic fatty acid synthase and S14 gene expression does not require peroxisome proliferator-activated receptor α J. Biol. Chem. 272:1997;26827-26832.
    • (1997) J. Biol. Chem. , vol.272 , pp. 26827-26832
    • Ren, B.1    Thelen, A.P.2    Peters, J.M.3    Gonzales, F.J.4    Jump, D.B.5
  • 30
    • 0014894763 scopus 로고
    • Growth and liver glycerophosphate dehydrogenase responses to thyroxine and p-chlorophenoxyisobutyrate
    • Richert D.A., Westerfeld W.W. Growth and liver glycerophosphate dehydrogenase responses to thyroxine and p-chlorophenoxyisobutyrate. Endocrinology. 87:1970;1274-1281.
    • (1970) Endocrinology , vol.87 , pp. 1274-1281
    • Richert, D.A.1    Westerfeld, W.W.2
  • 31
    • 0027292101 scopus 로고
    • Acyl-CoA synthetase mRNA expression is controlled by fibric-acid derivatives, feeding and liver proliferation
    • Schoonjans K., Staels B., Grimaldi P., Auwerx J. Acyl-CoA synthetase mRNA expression is controlled by fibric-acid derivatives, feeding and liver proliferation. Eur. J. Biochem. 216:1993;615-622.
    • (1993) Eur. J. Biochem. , vol.216 , pp. 615-622
    • Schoonjans, K.1    Staels, B.2    Grimaldi, P.3    Auwerx, J.4
  • 32
    • 0030602866 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation
    • Schoonjans K., Staels B., Auwerx J. The peroxisome proliferator-activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation. Biochim. Biophys. Acta. 1302:1996;93-109.
    • (1996) Biochim. Biophys. Acta , vol.1302 , pp. 93-109
    • Schoonjans, K.1    Staels, B.2    Auwerx, J.3
  • 33
    • 0029994543 scopus 로고    scopus 로고
    • Role of the peroxisome proliferator-activated receptors (PPARs) in mediating the effects of fibrates and fatty acids on gene expression
    • Schoonjans K., Staels B., Auwerx J. Role of the peroxisome proliferator-activated receptors (PPARs) in mediating the effects of fibrates and fatty acids on gene expression. J. Lipid Res. 37:1996;907-925.
    • (1996) J. Lipid Res. , vol.37 , pp. 907-925
    • Schoonjans, K.1    Staels, B.2    Auwerx, J.3
  • 36
    • 0017177024 scopus 로고
    • Acute effect in vivo of anti-insulin serum on rates of fatty acid synthesis activities of acetyl-Coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose of fed rats
    • Stansbie D., Brownsey R.W., Crettaz M., Denton R.M. Acute effect in vivo of anti-insulin serum on rates of fatty acid synthesis activities of acetyl-Coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose of fed rats. Biochem. J. 160:1976;413-416.
    • (1976) Biochem. J. , vol.160 , pp. 413-416
    • Stansbie, D.1    Brownsey, R.W.2    Crettaz, M.3    Denton, R.M.4
  • 37
    • 0019187194 scopus 로고
    • Fatty acid synthesis in brown adipose tissue in relation to whole body synthesis in the cold-acclimated golden hamster (Mesocricetus auratus)
    • Trayhurn P. Fatty acid synthesis in brown adipose tissue in relation to whole body synthesis in the cold-acclimated golden hamster (Mesocricetus auratus). Biochim. Biophys. Acta. 620:1980;10-17.
    • (1980) Biochim. Biophys. Acta , vol.620 , pp. 10-17
    • Trayhurn, P.1
  • 38
    • 0014700414 scopus 로고
    • Effect of clofibrate (ethyl-chlorophenoxyisobutyrate) feeding on glycolytic and lipogenic enzymes and hepatic glycogen synthesis in the rat
    • Zakim D., Paradini R.S., Herman R.H. Effect of clofibrate (ethyl-chlorophenoxyisobutyrate) feeding on glycolytic and lipogenic enzymes and hepatic glycogen synthesis in the rat. Biochem. Pharmacol. 19:1970;305-310.
    • (1970) Biochem. Pharmacol. , vol.19 , pp. 305-310
    • Zakim, D.1    Paradini, R.S.2    Herman, R.H.3
  • 39
    • 0020546645 scopus 로고
    • The effect of clofibrate feeding on the NADP-linked dehydrogenases activity in the rat tissue
    • Zelewski M., Swierczynski J. The effect of clofibrate feeding on the NADP-linked dehydrogenases activity in the rat tissue. Biochim. Biophys. Acta. 785:1983;152-157.
    • (1983) Biochim. Biophys. Acta , vol.785 , pp. 152-157
    • Zelewski, M.1    Swierczynski, J.2
  • 40
    • 0022631036 scopus 로고
    • The influence of prolonged clofibrate treatment on plasma drug concentration and liver NADP-linked enzymes activity
    • Zelewski M., Swierczynski J. The influence of prolonged clofibrate treatment on plasma drug concentration and liver NADP-linked enzymes activity. Gen. Pharmacol. 17:1986;117-119.
    • (1986) Gen. Pharmacol. , vol.17 , pp. 117-119
    • Zelewski, M.1    Swierczynski, J.2
  • 41
    • 0024507541 scopus 로고
    • Clofibrate feeding increases cytoplasmic but not mitochondrial malic enzyme activity in rat kidney cortex
    • Zelewski M., Swierczynski J. Clofibrate feeding increases cytoplasmic but not mitochondrial malic enzyme activity in rat kidney cortex. Cell Biochem. Funct. 7:1989;97-103.
    • (1989) Cell Biochem. Funct. , vol.7 , pp. 97-103
    • Zelewski, M.1    Swierczynski, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.