Involvement of gap junctions in bradykinin-induced relaxation of bovine pulmonary supernumerary arteries before and after inhibition of nitric oxide/guanylate cyclase

Clinical Science

Volumn 103, Issue 6, 2002, Pages 553-557

  Tracey, A ^a   MacDonald, A ^a   Shaw, Angus M ^a  

^a GLASGOW CALEDONIAN UNIVERSITY   (United Kingdom)

Author keywords

Carbenoxolone; Endothelium derived hyperpolarizing factor (EDHF); Gap junctions; Guanylate cyclase; Nitric oxide; Vascular endothelium

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; BRADYKININ; CAPTOPRIL; CARBENOXOLONE; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; GUANYLATE CYCLASE; HYDROXOCOBALAMIN; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL TISSUE; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; CATTLE; CONTROLLED STUDY; ENZYME INHIBITION; GAP JUNCTION; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY;

EID: 0036911817     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs1030553     Document Type: Article

References (24)

1. Tracey, A., Bunton, D., MacDonald, A. and Shaw, A. M. (2002) Relaxation to bradykinin in bovine pulmonary supernumerary arteries: role of nitric oxide and a guanylyl cyclase. Br. J. Pharmacol. 137, 538-544
2. Chaytor, A. T., Evans, W. H. and Griffith, T. M. (1998) Central role of heterocellular gap junctional communication in endothelium-dependent relaxations of rabbit arteries. J. Physiol. (Cambridge, U.K.) 508, 561-573
3. Dora, K. A., Martin, P. E. M., Chaytor, A. T., Evans, H., Garland, C. J. and Griffith, T. M. (1999) Role of heterocellular gap junctional communication in endothelium-dependent smooth muscle hyperpolarisation: Inhibition by a connexin-mimetic peptide. Biochem. Biophys. Res. Commun. 254, 27-31
4. Eawards, G., Feletou, M., Gardiner, M. J. and Thollon, C. (1999) Role of gap junctions in the responses to EDHF in rat and guinea-pig small arteries. Br. J. Pharmacol. 128, 1788-1794
5. Yamamoto, Y., Imaeda, K. and Suzuki, H. (1999) Endothelium-dependent hyperpolarisation and intercellular electrical coupling in guinea-pig mesenteric arterioles. J. Physiol. (Cambridge, U.K.) 514, 505-513
6. Christ, G. J. and Barr, L. (2000) The neuronal control of smooth muscle. In A Functional View of Smooth Muscle Control (Barr, L. and Christ, G. J., eds), pp. 345-396, JAI Press, Greenwich, CT
7. Bukauskas, F. F., Jordan, K., Bukauskiene, A. et al. (2000) Clustering of connexin43-enhanced green fluorescent protein gap junction channels and functional coupling in living cells. Proc. Natl. Acad. Sci. U.S.A. 97, 2556-2561
8. Brink, P. R., Valiunas, V. and Christ, G. R. (2000) Homotypic, heterotypic and heteromeric gap junction channels. Curr. Top. Membr. 49, 131-142
9. Beyer, E. C. (1993) Gap junctions. Int. Rev. Cytol. 137C, 1-37
10. Van Kempen, M. J. A. and Jongsma, H. J. (1999) Distribution of connexin 37, connexin 40 and connexin 43 in aorta and coronary artery of several mammals. Histochem. Cell Biol. 112, 479-486
11. Guan, X. J., Wilson, S., Schlender, K. K. and Ruch, R. J. (1996) Gap-junction disassembly and connexin 43 dephosphorylation induced by 18 beta-glycyrrhetinic acid. Mol. Carcinogen. 16, 157-164
12. Danser, A. H. J., Tom, B., de vries, R. and Saxena, P. R. (2000) L-NAME-resistant bradykinin-induced relaxation in porcine coronary arteries is NO-dependent: Effects of ACE inhibition. Br. J. Pharmacol. 131, 195-202
13. Schrammel, A., Behrends, S., Schmidt, K., Koesling, D. and Mayer, B. (1996) Characterization of 1H (1,2,4)-oxadiazolo (4,3-a)quinoxalin-1-one as a heme-site inhibitor of NO-sensitive guanylyl cyclase. Mol. Pharmacol. 50, 1-5
14. Chataigneau, T., Feletou, M., Duhault, J. and Vanhoutte, P. M. (1998) Epoxyeicotrienoic acids, potassium channel blockers and endothelium-dependent hyperpolarization in the guinea-pig carotid artery. Br. J. Pharmacol. 78, 574-580
15. Zygmunt, P. M. and Hogestatt, E. D. (1996) Role of potassium channels in endothelium-dependent relaxation resistant to nitroarginine in the rat hepatic artery. Br. J. Pharmacol. 117, 1600-1606
16. Petersson, J., Zygmunt, P. M. and Hogestatt, E. D. (1997) Characterization of the potassium channels involved in EDHF-mediated relaxation in cerebral arteries. Br. J. Pharmacol. 120, 1344-1350
17. + is an endothelium-derived hyperpolarizing factor in rat arteries. Nature (London) 396, 269-272
18. Cook, N. S. and Quast, U. (1990) Potassium channel pharmacology. In Potassium Channels: Structure, Classification, Function and Therapeutic Potential (Cook, N. S., ed.), pp. 181-325, Halsted Press, New York
19. Nelson, M. T. and Quayle, J. M. (1995) Physiological roles and properties of potassium channels in arterial smooth muscle. Am. J. Physiol. 268, C799-C822
20. Bauersachs, J., Popp, R., Hecker, M., Sauer, E., Fleming, I. and Busse, R. (1996) Nitric oxide attenuates the release of endothelium-derived hyperpolarizing factor. Circulation 94, 3341-3347
21. McCulloch, A. I., Bottrill, F. E., Randall, M. D. and Hiley, C. R. (1997) Characterization and modulation of EDHF-mediated relaxations in the rat isolated superior mesenteric arterial bed. Br. J. Pharmacol. 120, 1431-1438
22. 2+ channels. Br. J. Pharmacol. 117, 1035-1040
23. G-nitro-L-arginine in pulmonary hypertension. Br. J. Pharmacol. 116, 2457-2467
24. Kwak, B. R., Saez, J. C., Wilders, R. et al. (1995) Effects of cGMP-dependent phosphorylation on rat and human connexin 43 gap junction channels. Pflugers Arch. 430, 770-778