Vps10p cycles between the TGN and the late endosome via the plasma membrane in clathrin mutants

Molecular Biology of the Cell

Volumn 13, Issue 12, 2002, Pages 4296-4307

  Deloche, Olivier ^a,b   Schekman, Randy W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; CLATHRIN; GREEN FLUORESCENT PROTEIN; PROTEIN; PROTEIN CYP; PROTEIN TGN; PROTEIN VPS 10P; PROTEINASE; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; DNA; PEP1 PROTEIN, S CEREVISIAE; PHOTOPROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; VESICULAR TRANSPORT PROTEIN;

ARTICLE; CELL FRACTIONATION; CELL MEMBRANE; CELL SURFACE; CELL VACUOLE; ENDOSOME; GOLGI COMPLEX; MEMBRANE TRANSPORT; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TARGETING; PROTEIN TRANSPORT; SPHEROPLAST; STEADY STATE; BIOLOGICAL MODEL; FLUORESCENCE MICROSCOPY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; GENOTYPE; IMMUNOBLOTTING; METABOLISM; MUTATION; PLASMID; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; SERODIAGNOSIS; TIME; TRANS GOLGI NETWORK;

CELL MEMBRANE; CLATHRIN; DNA; ENDOSOMES; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENOTYPE; GOLGI APPARATUS; GREEN FLUORESCENT PROTEINS; IMMUNOBLOTTING; LUMINESCENT PROTEINS; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; MUTATION; PLASMIDS; PRECIPITIN TESTS; PROTEIN BINDING; RECEPTORS, CELL SURFACE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUBCELLULAR FRACTIONS; TIME FACTORS; TRANS-GOLGI NETWORK; VESICULAR TRANSPORT PROTEINS;

EID: 0036911346     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.02-07-0105     Document Type: Article

References (50)

1. Ausubel, F.M., Brent, R., Kingston, R.E., More, D.D., Seidman, J.G., Smith, J.A., and Struhl, K. (1987-1995). Current Protocols in Molecular Biology. New York: John Wiley, and Sons, Inc.
2. Becherer, K.A., Rieder, S.E., Emr, S.D., and Jones, E.W. (1996). Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the lysosome-like vacuole in yeast. Mol. Biol. Cell 7, 579-594.
3. Black, M.W., and Pelham, H.R. (2000). A selective transport route from Golgi to late endosomes that requires file yeast GGA proteins. J. Cell Biol. 151, 587-600.
4. Bryant, N.J., Piper, R.C., Gerrard, S.R., and Stevens, T.H. (1998). Traffic into the prevacuolar/endosomal compartment of Saccharomyces cerevisiae: A VPS45-dependent intracellular route and a VPS45-independent, endocytic route. Eur J. Cell Biol. 76, 43-52.
5. Burd, C.G., Peterson, M., Cowles, C.R., and Emr, S.D. (1997) A novel Sec18p/NSF-dependent complex required for Golgi-to-endosome transport in yeast. Mol. Biol. Cell 8, 1089-1104.
6. Chen, C.Y., and Graham, T.R. (1998). An arf1 Delta synthetic lethal screen identifies a new clathrin heavy chain conditional allele that perturbs vacuolar protein transport in Saccharomyces cerevisiae. Genetics 150, 577-589.
7. Chu, D.S., Pishvaee, B., and Payne, G.S. (1996). The light chain subunit is required for clathrin function in Saccharomyces cerevisiae. J. Biol. Chem. 271, 33123-33130.
8. Chuang, J.S., and Schekman, R.W. (1996). Differential trafficking and timed localization of two chitin synthase proteins, Chs2p and Chs3p. J. Cell Biol. 135, 597-610.
9. Cooper, A.A., and Stevens, T.H. (1996). Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases. J. Cell Biol. 133, 529-541.
10. Davis, N.G., Horecka, J.L., and Sprague, G.F., Jr. (1993). Cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors. J. Cell Biol. 122, 53-65.
11. Deloche, O., Yeung, B.G., Payne, G.S., and Schekman, R. (2001). Vps10p transport from the trans-Golgi network to the endosome is mediated by clathrin-coated vesicles. Mol. Biol. Cell 12, 475-485.
12. Draper, R.K., Goda, Y., Brodsky, F.M., and Pfeffer, S.R. (1990). Antibodies to clathrin inhibit endocytosis but not recycling to the trans Golgi network in vitro. Science 248, 1539-1541.
13. Feldheim, D., Yoshimura, K., Admon, A., and Schekman, R. (1993). Structural and functional characterization of Sec66p, a new submit of the polypeptide translocation apparatus in the yeast endoplasmic reticulum. Mol. Biol. Cell 4, 931-939.
14. Goda, Y., and Pfeffer, S.R. (1991). Identification of a novel, N-ethylmaleimide-sensitive cytosolic factor required for vesicular transport from endosomes to the trans-Golgi network in vitro. J. Cell Biol. 112, 823-831.
15. Guthrie, C., and Fink, G.R. (1991). Guide to yeast genetics and molecular biology. Methods Enzymol. 194, 3-21.
16. Harsay, E., and Bretscher, A. (1995). Parallel secretory pathways to the cell surface in yeast. J. Cell Biol. 131, 297 310.
17. Harsay, E., and Schekman, R. (2002). A subset of yeast vacuolar protein sorting mutants is blocked in one branch of the exocytic pathway. J. Cell Biol. 156, 271-285.
18. Holthuis, J.C., Nichols, B.J., Dhruvakumar, S., and Pelham, H.R. (1998a). Two syntaxin homologues in the TGN/endosomal system of yeast. EMBO J. 77, 113-126.
19. Holthuis, J.C., Nichols, B.J., and Pelham, H.R. (1998b). The syntaxin Tlglp mediates trafficking of chitin synthase III to polarized growth sites in yeast. Mol. Biol. Cell 9, 3383-3397.
20. Humair, D., Hernández Felipe, D., Neuhaus, J.-M., and Paris, N. (2001). Demonstration in yeast of the function of BP-80, a putative plant vacuolar sorting receptor. Plant Cell 13, 781-792.
21. Kornfeld, S. (1992). Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors. Annu. Rev. Biochem. 61, 307-330.
22. Lewis, M.J., Nichols, B.J., Prescianotto-Baschong, C., Riezman, H., and Pelham, H.R. (2000). Specific retrieval of the exocytic SNARE Snc1p from early yeast endosomes. Mol. Biol. Cell 11, 23-38.
23. Marcusson, E.G., Horazdovsky, B.F., Cereghino, J.L., Gharakhanian, E., and Emr, S.D. (1994). The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene. Cell 77, 579-586.
24. Nicoziani, P., Vilhardt, F., Llorente, A., Hilout, L., Courtoy, P.J., Sandvig, K., and van Deurs, B. (2000). Role for dynamin in late endosome dynamics and trafficking of the cation-independent mannose 6-phosphate receptor. Mol. Biol. Cell 11, 481-495.
25. Nothwehr, S.F., Bruinsma, P., and Strawn, L.A. (1999). Distinct domains within Vps35p mediate the retrieval of two different cargo proteins from the yeast prevacuolar/endosomal compartment. Mol. Biol. Cell 10, 875-890.
26. Nothwehr, S.F., Conibear, E., and Stevens, T.H. (1995). Golgi and vacuolar membrane proteins reach the vacuole in vpsl mutant yeast cells via the plasma membrane. J. Cell Biol. 129, 35-46.
27. Nothwehr, S.F., Ha, S.A., and Bruinsma, P. (2000). Sorting of yeast membrane proteins into an endosome-to-Golgi pathway involves direct interaction of their cytosolic domains with Vps35p. J. Cell Biol. 151, 297-310.
28. Nothwehr, S.F., Roberts, C.J., and Stevens, T.H. (1993). Membrane protein retention in the yeast Golgi apparatus: Dipeptidyl aminopeptidase A is retained by a cytoplasmic signal containing aromatic residues. J. Cell Biol. 121, 1197-1209.
29. Payne, G., Baker, D., Van Tuinen, E., and Schekman, R. (1988). Protein transport to the vacuole and receptor-mediated endocytosis by clathrin heavy chain-deficient yeast. J. Cell Biol. 106, 1453-1461.
30. Payne, G.S., and Schekman, R. (1989). Clathrin: A role in the intracellular retention of a Golgi membrane protein. Science 245, 1358-1365.
31. Piper, R., Bryant, N., and Stevens, T. (1997). The membrane protein alkaline phosphatase is delivered to the vacuole by a route that is distinct from the VPS-dependent pathway. J. Cell Biol. 138, 531-546.
32. Pishvaee, B., Costaguta, G., Yeung, B.G., Ryazantsev, S., Greener, T., Greene, L.E., Eisenberg, E., McCaffery, J.M., and Payne, G.S. (2000). A yeast DNA J protein required for uncoating of clathrin-coated vesicles in vivo. Nat. Cell Biol. 2, 958-963.
33. Rad, M.R., Phan, H.L., Kirchrath, L., Tan, P.K., Kirchhausen, T., Hollenberg, C.P., and Payne, G.S. (1995). Saccharomyces cerevisiae Apl2p, a homologue of the mammalian clathrin AP beta subunit, plays a role in clathrin-dependent Golgi functions. J. Cell Sci. 108, 1605-1615.
34. Redding, K., Holcomb, C., and Fuller, R.S. (1991). Immurolocalization of Kex2 protease identifies a putative late Golgi compartment in the yeast Saccharomyces cerevisiae. J. Cell Biol. 113, 527-538.
35. Redding, K., Seeger, M., Payne, G.S., and Fuller, R.S. (1996). The effects of clathrin inactivation on localization of Kex2 protease are independent of the TGN localization signal in the cytosolic tail of Kex2p. Mol. Biol. Cell 7,1667-1677.
36. Roberts, C.J., Nothwehr, S.F., and Stevens, T.H. (1992). Membrane protein sorting in the yeast secretory pathway: Evidence that the vacuole may be the default compartment. J. Cell Biol. 119, 69-83.
37. Roth, A.F., Sullivan, D.M., and Davis, N.G. (1998). A large PEST-like sequence directs the ubiquitination, endocytosis, and vacuolar degradation of the yeast a-factor receptor. J. Cell Biol. 142, 949-961.
38. Rothman, J.H., Raymond, C.K., Gilbert, T., O'Hara, P.J., and Stevens, T.H. (1990). A putative GTP binding protein homologous to interferon-inducible Mx proteins performs an essential function in yeast protein sorting. Cell 61, 1063-1074.
39. Schekman, R., and Orci, L. (1996). Coat proteins and vesicle budding. Science 271, 1526-1533.
40. Schmid, S.L. (1997). Clathrin-coated vesicle formation and protein sorting: An integrated process. Annu. Rev. Biochem. 66, 511-548.
41. Seaman, M.N., Marcusson, E.G., Cereghino, J.L., and Emr, S.D. (1997). Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products. J. Cell Biol. 137, 79-92.
42. Seaman, M.N., McCaffery, J.M., and Emr, S.D. (1998). A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast. J., Cell Biol. 142, 665-681.
43. Seeger, M., and Payne, G.S. (1992). A role for clathrin in the sorting of vacuolar proteins in the Golgi complex of yeast. EMBO J. 11, 2811-2818.
44. Silveira, L.A., Wong, D.H., Masiarz, F.R., and Schekman, R. (1990). Yeast clathrin has a distinctive light chain that is important for cell growth. J. Cell Biol. 111, 1437-1449.
45. Springer, S., Spang, A., and Schekman R. (1999). A primer on vesicle budding. Cell 97, 145-148.
46. Stevens, T., Esmon, B., and Schekman, R. (1982). Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole. Cell 30, 439-448.
47. Tan, P.K., Davis, N.G., Sprague, G.F., and Payne, G.S. (1993). Clathrin facilitates the internalization of seven transmembrane segment receptors for mating pheromones in yeast. J. Cell Biol. 123, 1707-1716.
48. Vater, C.A., Raymond, C.K., Ekena, K., Howald-Stevenson, I., and Stevens, T.H. (1992). The VPS1 protein, a homolog of dynamin required for vacuolar protein sorting in Saccharomyces cerevisiae, is a GTPase with two functionally separable domains. J. Cell Biol. 119, 773-786.
49. Vida, T.A., and Emr, S.D. (1995). A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast. J. Cell Biol. 128, 779-792.
50. Wilcox, C.A., Redding, K., Wright, R., and Fuller, R.S. (1992). Mutation of a tyrosine localization signal in the cytosolic tail of yeast Kex2 protease disrupts Golgi retention and results in default transport to the vacuole. Mol. Biol. Cell 3, 1353-1371.