메뉴 건너뛰기




Volumn 142, Issue 4, 1998, Pages 949-961

A large PEST-like sequence directs the ubiquitination, endocytosis, and vacuolar degradation of the yeast a-factor receptor

Author keywords

Endocytosis; Pheromone; Receptors; Saccharomyces cerevisiae; Ubiquitin

Indexed keywords

ADENOSINE TRIPHOSPHATASE; RECEPTOR; UNCLASSIFIED DRUG; YEAST A FACTOR RECEPTOR;

EID: 0032563560     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.142.4.949     Document Type: Article
Times cited : (84)

References (41)
  • 1
    • 15444350364 scopus 로고
    • Yeast peptide pheromones, a-factor and α-factor, activate a common response mechanism in their target cells
    • Bender, A., and G.F. Sprague. Jr. 1986. Yeast peptide pheromones, a-factor and α-factor, activate a common response mechanism in their target cells. Cell. 15:919-933.
    • (1986) Cell , vol.15 , pp. 919-933
    • Bender, A.1    Sprague Jr., G.F.2
  • 2
    • 0026019441 scopus 로고
    • Half-life of the plasma membrane ATPase and its activating system in resting yeast cells
    • Benito, B., E. Moreno, and R. Lagunas. 1991. Half-life of the plasma membrane ATPase and its activating system in resting yeast cells. Biochim. Biophys. Acta. 1063:265-268.
    • (1991) Biochim. Biophys. Acta , vol.1063 , pp. 265-268
    • Benito, B.1    Moreno, E.2    Lagunas, R.3
  • 3
    • 0023484186 scopus 로고
    • 5-Fluoroorotic acid as a selective agent in yeast molecular genetics
    • Boeke, J.D., J. Trueheart, J. Natsoulis, and G.R. Fink. 1987. 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol. 154:164-175.
    • (1987) Methods Enzymol. , vol.154 , pp. 164-175
    • Boeke, J.D.1    Trueheart, J.2    Natsoulis, J.3    Fink, G.R.4
  • 4
    • 12044260162 scopus 로고
    • Mutations that alter the third cytoplasmic loop of the a-factor receptor lead to a constitutive and hypersensitive phenotype
    • Boone, C., N.G. Davis, and G. Sprague, Jr. 1993. Mutations that alter the third cytoplasmic loop of the a-factor receptor lead to a constitutive and hypersensitive phenotype. Proc. Natl. Acad. Sci. USA. 90:9921-9925.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9921-9925
    • Boone, C.1    Davis, N.G.2    Sprague Jr., G.3
  • 5
    • 0028018268 scopus 로고
    • The ubiquitin-proteosome proteolytic pathway
    • Ciechanover, A. 1994. The ubiquitin-proteosome proteolytic pathway. Cell. 79: 13-21.
    • (1994) Cell , vol.79 , pp. 13-21
    • Ciechanover, A.1
  • 6
    • 0024150158 scopus 로고
    • Response of yeast a cells to a-factor pheromone: Topology of the receptor and identification of a component of the response pathway
    • Clark, K.L., N.G. Davis, D.K. Wiest, J.-J. Hwang-Shum, and G.F. Sprague, Jr. 1988. Response of yeast a cells to a-factor pheromone: topology of the receptor and identification of a component of the response pathway. Cold Spring Harbor Symp. Quant. Biol. 53:611-620.
    • (1988) Cold Spring Harbor Symp. Quant. Biol. , vol.53 , pp. 611-620
    • Clark, K.L.1    Davis, N.G.2    Wiest, D.K.3    Hwang-Shum, J.-J.4    Sprague Jr., G.F.5
  • 7
    • 0027175829 scopus 로고
    • Cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors
    • Davis, N.G., J.L. Horecka, and G.F. Sprague, Jr. 1993. Cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors. J. Cell Biol. 122:53-65.
    • (1993) J. Cell Biol. , vol.122 , pp. 53-65
    • Davis, N.G.1    Horecka, J.L.2    Sprague Jr., G.F.3
  • 8
    • 0030041980 scopus 로고    scopus 로고
    • The yeast multidrug transporter Pdr5 of the plasma membrane is ubiquitinated prior to endocytosis and degradation in the vacuole
    • Egner, R., and K. Kuchler. 1996. The yeast multidrug transporter Pdr5 of the plasma membrane is ubiquitinated prior to endocytosis and degradation in the vacuole. FEBS (Fed. Eur. Biochem. Soc.) Lett. 378:177-181.
    • (1996) FEBS (Fed. Eur. Biochem. Soc.) Lett. , vol.378 , pp. 177-181
    • Egner, R.1    Kuchler, K.2
  • 9
    • 0025838227 scopus 로고
    • Epitope-tagged ubiquitin: A new probe for analyzing ubiquitin function
    • Ellison, M.J., and M. Hochstrasser. 1991. Epitope-tagged ubiquitin: a new probe for analyzing ubiquitin function. J. Biol. Chem. 266:21150-21157.
    • (1991) J. Biol. Chem. , vol.266 , pp. 21150-21157
    • Ellison, M.J.1    Hochstrasser, M.2
  • 10
    • 0030881952 scopus 로고    scopus 로고
    • Ubiquitin Lys63 is involved in ubiquitination and endocytosis of a yeast plasma membrane protein
    • Galan, J., and R. Haguenauer-Tsapis. 1997. Ubiquitin Lys63 is involved in ubiquitination and endocytosis of a yeast plasma membrane protein. EMBO (Eur. Mol. Biochem. Organ.) J. 16:5847-5854.
    • (1997) EMBO (Eur. Mol. Biochem. Organ.) J. , vol.16 , pp. 5847-5854
    • Galan, J.1    Haguenauer-Tsapis, R.2
  • 11
    • 15844424064 scopus 로고    scopus 로고
    • Ubiquitination mediated by the Npi1p/Rsp5p ubiquitin-protein ligase is required for endocytosis of the yeast uracil permease
    • Galan, J.M., V. Moreau, B. Andre, C. Volland, and R. Haguenauer-Tsapis. 1996. Ubiquitination mediated by the Npi1p/Rsp5p ubiquitin-protein ligase is required for endocytosis of the yeast uracil permease. J. Biol. Chem. 271: 10946-10952.
    • (1996) J. Biol. Chem. , vol.271 , pp. 10946-10952
    • Galan, J.M.1    Moreau, V.2    Andre, B.3    Volland, C.4    Haguenauer-Tsapis, R.5
  • 12
    • 0030855771 scopus 로고    scopus 로고
    • The ankyrin repeat-containing protein Akr1p is required for the endocytosis of yeast pheromone receptors
    • Givans, S.A., and G.F. Sprague, Jr. 1997. The ankyrin repeat-containing protein Akr1p is required for the endocytosis of yeast pheromone receptors. Mol. Biol. Cell. 8:1317-1327.
    • (1997) Mol. Biol. Cell. , vol.8 , pp. 1317-1327
    • Givans, S.A.1    Sprague Jr., G.F.2
  • 13
    • 0030797998 scopus 로고    scopus 로고
    • Linkage of the ubiquitin-conjugating system and the endocytic pathway in ligand-induced internalization of the growth hormone receptor
    • Gowers, R., P. van Kerkhof, A.L. Schwartz, and G.J. Strous. 1997. Linkage of the ubiquitin-conjugating system and the endocytic pathway in ligand-induced internalization of the growth hormone receptor. EMBO (Eur. Mol. Biochem. Organ.) J. 16:4851-4858.
    • (1997) EMBO (Eur. Mol. Biochem. Organ.) J. , vol.16 , pp. 4851-4858
    • Gowers, R.1    Van Kerkhof, P.2    Schwartz, A.L.3    Strous, G.J.4
  • 14
    • 0009447741 scopus 로고
    • Evidence that the yeast STE3 gene encodes a receptor for peptide pheromone a-factor
    • Hagen, D.C., G. McCaffrey, and G.F. Sprague, Jr. 1986. Evidence that the yeast STE3 gene encodes a receptor for peptide pheromone a-factor. Proc. Natl. Acad. Sci. USA. 83:1418-1422.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 1418-1422
    • Hagen, D.C.1    McCaffrey, G.2    Sprague Jr., G.F.3
  • 16
    • 0028971506 scopus 로고
    • NP11, an essential yeast gene involved in induced degradation of Gap1 and Fur4 permeases, encodes the Rsp5 ubiquitin-protein ligase
    • Hein, C., J.-Y. Springael, C. Volland, R. Haguenauer-Tsapis, and B. Andre. 1995. NP11, an essential yeast gene involved in induced degradation of Gap1 and Fur4 permeases, encodes the Rsp5 ubiquitin-protein ligase. Mol. Microbiol 18:77-87.
    • (1995) Mol. Microbiol , vol.18 , pp. 77-87
    • Hein, C.1    Springael, J.-Y.2    Volland, C.3    Haguenauer-Tsapis, R.4    Andre, B.5
  • 17
    • 0030054178 scopus 로고    scopus 로고
    • Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis
    • Hicke, L., and H. Riezman. 1996. Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis. Cell. 84:277-287.
    • (1996) Cell , vol.84 , pp. 277-287
    • Hicke, L.1    Riezman, H.2
  • 18
    • 0032550179 scopus 로고    scopus 로고
    • Cyloplasmic tail phosphorylation of the α-factor receptor is required for ubiquitination and internalization
    • Hicke, L., B. Zanolari, and H. Riezman. 1998. Cyloplasmic tail phosphorylation of the α-factor receptor is required for ubiquitination and internalization. J. Cell Biol. 141:359-371.
    • (1998) J. Cell Biol. , vol.141 , pp. 359-371
    • Hicke, L.1    Zanolari, B.2    Riezman, H.3
  • 19
    • 0030457014 scopus 로고    scopus 로고
    • Ubiquitin-dependent protein degradation
    • Hochstrasser, M. 1996. Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30:405-439.
    • (1996) Annu. Rev. Genet. , vol.30 , pp. 405-439
    • Hochstrasser, M.1
  • 20
    • 0028277963 scopus 로고
    • The ABC-transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants
    • Kolling, R., and C.P. Hollenberg. 1994. The ABC-transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants. EMBO (Eur. Mol. Biochem. Organ.) J. 13:3261-3271.
    • (1994) EMBO (Eur. Mol. Biochem. Organ.) J. , vol.13 , pp. 3261-3271
    • Kolling, R.1    Hollenberg, C.P.2
  • 21
    • 0040123316 scopus 로고    scopus 로고
    • The linker region of the ABC-transporter Ste6 mediates ubiquitination and fast turnover of the protein
    • Kolling, R., and S. Losko. 1997. The linker region of the ABC-transporter Ste6 mediates ubiquitination and fast turnover of the protein. EMBO (Eur. Mol). Biochem. Organ.) J. 16:2251-2261.
    • (1997) EMBO (Eur. Mol). Biochem. Organ. J. , vol.16 , pp. 2251-2261
    • Kolling, R.1    Losko, S.2
  • 22
    • 0023613953 scopus 로고
    • Rapid and efficient sitespecific mutagenesis without phenotypic selection
    • Kunkel, T.A., J.D. Roberts, and R.A. Zakour. 1987. Rapid and efficient sitespecific mutagenesis without phenotypic selection. Methods Enzymol. 154: 367-382.
    • (1987) Methods Enzymol. , vol.154 , pp. 367-382
    • Kunkel, T.A.1    Roberts, J.D.2    Zakour, R.A.3
  • 23
    • 0031950846 scopus 로고    scopus 로고
    • Role of the ubiquitin-proteosome system in the vacuolar degradation of Ste6p. the a-factor transporter in Saccharomyces cerevisiae
    • Loaza, D., and S. Michaelis. 1998. Role of the ubiquitin-proteosome system in the vacuolar degradation of Ste6p. the a-factor transporter In Saccharomyces cerevisiae. Mol. Cell. Biol. 18:779-789.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 779-789
    • Loaza, D.1    Michaelis, S.2
  • 24
    • 0031055949 scopus 로고    scopus 로고
    • Catabolite inactivation of the yeast maltose transporter requires ubiquitin-ligase npi1/rsp5 and ubiquitin-hydrolase npi2/doa4
    • Lucero, P., and R. Lagunas. 1997. Catabolite inactivation of the yeast maltose transporter requires ubiquitin-ligase npi1/rsp5 and ubiquitin-hydrolase npi2/doa4. FEMS (Fed. Eur. Microbiol. Soc.) Microbiol. Lett. 147:273-277.
    • (1997) FEMS (Fed. Eur. Microbiol. Soc.) Microbiol. Lett. , vol.147 , pp. 273-277
    • Lucero, P.1    Lagunas, R.2
  • 25
    • 0031961993 scopus 로고    scopus 로고
    • A PEST-like sequence mediates phosphorylation and efficient ubiquitination of yeast uracil permease
    • Marchal, C., R. Haguenauer-Tsapis, and D. Urban-Grimal. 1998. A PEST-like sequence mediates phosphorylation and efficient ubiquitination of yeast uracil permease. Mol. Cell. Biol. 18:314-321.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 314-321
    • Marchal, C.1    Haguenauer-Tsapis, R.2    Urban-Grimal, D.3
  • 26
    • 0029752791 scopus 로고    scopus 로고
    • Endocytosis and molecular sorting
    • Mellman, I. 1996. Endocytosis and molecular sorting. Annu. Rev. Cell Dev. Biol. 12:575-625.
    • (1996) Annu. Rev. Cell Dev. Biol. , vol.12 , pp. 575-625
    • Mellman, I.1
  • 27
    • 0023891818 scopus 로고
    • Protein transport to the vacuole and receptor-mediated endocytosis by clathrin heavy chain-deficient yeast
    • Payne, G.S., D. Baker, E. van Tuinen, and R. Schekman. 1988. Protein transport to the vacuole and receptor-mediated endocytosis by clathrin heavy chain-deficient yeast. J. Cell Biol. 106:1453-1461.
    • (1988) J. Cell Biol. , vol.106 , pp. 1453-1461
    • Payne, G.S.1    Baker, D.2    Van Tuinen, E.3    Schekman, R.4
  • 28
    • 0027455339 scopus 로고
    • end3 and end4: Two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cerevisiae
    • Raths, S., J. Rohrer, F. Crausaz, and H. Riezman. 1993. end3 and end4: Two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cerevisiae. J. Cell Biol. 120:55-65.
    • (1993) J. Cell Biol. , vol.120 , pp. 55-65
    • Raths, S.1    Rohrer, J.2    Crausaz, F.3    Riezman, H.4
  • 29
    • 0030200110 scopus 로고    scopus 로고
    • PEST sequences and regulation by proteolysis
    • Rechsteiner, M., and S.W. Rogers. 1996. PEST sequences and regulation by proteolysis. Trends Biochem. Sci. 21:267-271.
    • (1996) Trends Biochem. Sci. , vol.21 , pp. 267-271
    • Rechsteiner, M.1    Rogers, S.W.2
  • 30
    • 0030476867 scopus 로고    scopus 로고
    • Actin-, myosin- and ubiquitin-dependent endocytosis
    • Riezman, H., A. Munn, M.I. Geli, and L. Hicke. 1996. Actin-, myosin- and ubiquitin-dependent endocytosis. Experientia (Basel). 52:1033-1041.
    • (1996) Experientia (Basel) , vol.52 , pp. 1033-1041
    • Riezman, H.1    Munn, A.2    Geli, M.I.3    Hicke, L.4
  • 31
    • 0022971952 scopus 로고
    • Amino acid sequences common to rapidly degraded proteins: The PEST hypothesis
    • Rogers, S., R. Wells, and M. Rechsteiner. 1986. Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis. Science. 234:364-368.
    • (1986) Science , vol.234 , pp. 364-368
    • Rogers, S.1    Wells, R.2    Rechsteiner, M.3
  • 32
    • 0027207946 scopus 로고
    • Identification of a novel sequence mediating regulated endocytosis of the G-protein-coupled α-pheromone receptor in yeast
    • Rohrer, J., H. Benedetti, B. Zanolari, and H. Riezman. 1993. Identification of a novel sequence mediating regulated endocytosis of the G-protein-coupled α-pheromone receptor in yeast. Mol. Biol. Cell. 4:511-521.
    • (1993) Mol. Biol. Cell , vol.4 , pp. 511-521
    • Rohrer, J.1    Benedetti, H.2    Zanolari, B.3    Riezman, H.4
  • 33
    • 0023545322 scopus 로고
    • A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector
    • Rose, M.D., P. Novick, J.H. Thomas, D. Botstein, and G.R. Fink. 1987. A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene. 60:237-243.
    • (1987) Gene , vol.60 , pp. 237-243
    • Rose, M.D.1    Novick, P.2    Thomas, J.H.3    Botstein, D.4    Fink, G.R.5
  • 34
    • 0029781462 scopus 로고    scopus 로고
    • Ubiquitination of the yeast a-factor receptor
    • Roth, A.F., and N.G. Davis. 1996. Ubiquitination of the yeast a-factor receptor. J. Cell Biol. 134:661-674.
    • (1996) J. Cell Biol. , vol.134 , pp. 661-674
    • Roth, A.F.1    Davis, N.G.2
  • 35
    • 0030957355 scopus 로고    scopus 로고
    • Clathrin-coated vesicle formation and protein sorting: An integrated process
    • Schmid, S.L. 1997. Clathrin-coated vesicle formation and protein sorting: an integrated process. Annu. Rev. Biochem. 66:511-548.
    • (1997) Annu. Rev. Biochem. , vol.66 , pp. 511-548
    • Schmid, S.L.1
  • 36
    • 0024669291 scopus 로고
    • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski, R.S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics. 122:19-27.
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.2
  • 37
    • 0029765099 scopus 로고    scopus 로고
    • The ubiquitin conjugation system is required for ligand-induced endocytosis and degradation of the growth hormone receptor
    • Strous, G.J., P. van Kerkhof, R. Govers, A. Ciechanover, and A.L. Schwartz. 1996. The ubiquitin conjugation system is required for ligand-induced endocytosis and degradation of the growth hormone receptor. EMBO (Eur. Mol. Biochem. Organ.) J. 15:3806-3812.
    • (1996) EMBO (Eur. Mol. Biochem. Organ.) J. , vol.15 , pp. 3806-3812
    • Strous, G.J.1    Van Kerkhof, P.2    Govers, R.3    Ciechanover, A.4    Schwartz, A.L.5
  • 38
    • 0027752442 scopus 로고
    • Clathrin facilitates the internalization of seven transmembrane segment receptors for mating pheromones in yeast
    • Tan, P.K., N.G. Davis, G.F. Sprague, Jr., and G.S. Payne. 1993. Clathrin facilitates the internalization of seven transmembrane segment receptors for mating pheromones in yeast. J. Cell Biol. 123:1707-1716.
    • (1993) J. Cell Biol. , vol.123 , pp. 1707-1716
    • Tan, P.K.1    Davis, N.G.2    Sprague Jr., G.F.3    Payne, G.S.4
  • 39
    • 0030459065 scopus 로고    scopus 로고
    • The sequence NPFXD defines a new class of endocytosis signal in Saccharomyces cerevisiae
    • Tan, P.K., J.P. Howard, and G.S. Payne. 1996. The sequence NPFXD defines a new class of endocytosis signal in Saccharomyces cerevisiae. J. Cell Biol. 135: 1789-1800.
    • (1996) J. Cell Biol. , vol.135 , pp. 1789-1800
    • Tan, P.K.1    Howard, J.P.2    Payne, G.S.3
  • 40
    • 0031603760 scopus 로고    scopus 로고
    • A function for monoubiquitination in the internalization of a G protein-coupled receptor
    • Terrell, J., S. Shih, R. Dunn, and L. Hicke. 1998. A function for monoubiquitination in the internalization of a G protein-coupled receptor. Mol. Cell. 1:193-202.
    • (1998) Mol. Cell , vol.1 , pp. 193-202
    • Terrell, J.1    Shih, S.2    Dunn, R.3    Hicke, L.4
  • 41
    • 1842374437 scopus 로고    scopus 로고
    • MDP1, a Saccharomyces cerevisiae gene involved in mitochondrial/cytoplasmic protein distribution, is identical to the ubiquitin-protein ligase gene RSP5
    • Zolladek, T., A. Tobiasz, G. Vaduva, M. Boguta, N.C. Martin, and A.K. Hopper. 1997. MDP1, a Saccharomyces cerevisiae gene involved in mitochondrial/cytoplasmic protein distribution, is identical to the ubiquitin-protein ligase gene RSP5. Genetics. 145:595-603.
    • (1997) Genetics , vol.145 , pp. 595-603
    • Zolladek, T.1    Tobiasz, A.2    Vaduva, G.3    Boguta, M.4    Martin, N.C.5    Hopper, A.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.