-
1
-
-
0028920098
-
Prolines and amyloidogenicity in fragments of the Alzheimer's peptide beta/A4
-
Wood SJ, Wetzel R, Martin JD, Hurle MR. Prolines and amyloidogenicity in fragments of the Alzheimer's peptide beta/A4. Biochemistry 1995; 34:724-30.
-
(1995)
Biochemistry
, vol.34
, pp. 724-730
-
-
Wood, S.J.1
Wetzel, R.2
Martin, J.D.3
Hurle, M.R.4
-
2
-
-
0033538015
-
Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in vitro
-
Kayed R, Bernhagen J, Greenfield N, Sweimeh K, Brunner H, Voelter W, et al. Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in vitro. J Mol Biol 1999; 287:781-96.
-
(1999)
J. Mol. Biol.
, vol.287
, pp. 781-796
-
-
Kayed, R.1
Bernhagen, J.2
Greenfield, N.3
Sweimeh, K.4
Brunner, H.5
Voelter, W.6
-
3
-
-
0022547855
-
X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation
-
[published erratum appears Proc Natl Acad Sci USA 1986; 83:2776]
-
Kirschner DA, Abraham C, Selkoe DJ. X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation [published erratum appears in Proc Natl Acad Sci USA 1986; 83:2776]. Proc Natl Acad Sci USA 1986; 83:503-7.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 503-507
-
-
Kirschner, D.A.1
Abraham, C.2
Selkoe, D.J.3
-
4
-
-
0027363264
-
Transthyretin mutation Leu-55-Pro significantly alters tetramer stability and increases amyloidogenicity
-
McCutchen SL, Colon W, Kelly JW. Transthyretin mutation Leu-55-Pro significantly alters tetramer stability and increases amyloidogenicity. Biochemistry 1993; 32:12119-27.
-
(1993)
Biochemistry
, vol.32
, pp. 12119-12127
-
-
McCutchen, S.L.1
Colon, W.2
Kelly, J.W.3
-
5
-
-
0035920156
-
Tetramer dissociation and monomer partial unfolding precedes protofibril formation in amyloidogenic transthyretin variants
-
Quintas A, Vaz DC, Cardoso I, Saraiva MJ, Brito RM. Tetramer dissociation and monomer partial unfolding precedes protofibril formation in amyloidogenic transthyretin variants. J Biol Chem 2001; 276:27207-13.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27207-27213
-
-
Quintas, A.1
Vaz, D.C.2
Cardoso, I.3
Saraiva, M.J.4
Brito, R.M.5
-
6
-
-
0035949432
-
An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured
-
Jiang X, Smith CS, Petrassi HM, Hammarstrom P, White JT, Sacchettini JC, etal. An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured. Biochemistry 2001; 40:11442-52.
-
(2001)
Biochemistry
, vol.40
, pp. 11442-11452
-
-
Jiang, X.1
Smith, C.S.2
Petrassi, H.M.3
Hammarstrom, P.4
White, J.T.5
Sacchettini, J.C.6
-
7
-
-
0035909981
-
The V122l cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis
-
Jiang X, Buxbaum JN, Kelly JW. The V122l cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis. Proc Natl Acad Sci USA 2001; 98:14943-8.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 14943-14948
-
-
Jiang, X.1
Buxbaum, J.N.2
Kelly, J.W.3
-
8
-
-
0035180285
-
Deposition of transthyretin in early stages of familial amyloidotic polyneuropathy: Evidence for toxicity of non-fibrillar aggregates
-
Sousa MM, Cardoso I, Fernandes R, Guimaraes A, Saraiva MJ. Deposition of transthyretin in early stages of familial amyloidotic polyneuropathy: evidence for toxicity of non-fibrillar aggregates. Am J Pathol 2001; 159:1993-2000.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 1993-2000
-
-
Sousa, M.M.1
Cardoso, I.2
Fernandes, R.3
Guimaraes, A.4
Saraiva, M.J.5
-
9
-
-
0036290276
-
Only amyloidogenic intermediates of transthyretin induce apoptosis
-
Andersson K, Olofsson A, Nielsen EH, Svehag SE, Lundgren E. Only amyloidogenic intermediates of transthyretin induce apoptosis. Biochem Biophys Res Commun 2002; 294:309-14.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.294
, pp. 309-314
-
-
Andersson, K.1
Olofsson, A.2
Nielsen, E.H.3
Svehag, S.E.4
Lundgren, E.5
-
10
-
-
0036669881
-
Amyloid-beta oligomers: Their production, toxicity and therapeutic inhibition
-
Walsh DM, Kiyubin I, Fadeeva JV, Rowan MJ, Selkoe DJ. Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition. Biochem Soc Trans 2002; 30:552-7.
-
(2002)
Biochem. Soc. Trans.
, vol.30
, pp. 552-557
-
-
Walsh, D.M.1
Kiyubin, I.2
Fadeeva, J.V.3
Rowan, M.J.4
Selkoe, D.J.5
-
11
-
-
0030968128
-
Characterization of two highly amyloidogenic mutants of transthyretin
-
Goldsteins G, Andersson K, Olofsson A, Dacklin I, Edvinsson A, Baranov V, et al. Characterization of two highly amyloidogenic mutants of transthyretin. Biochemistry 1997; 36:5346-52.
-
(1997)
Biochemistry
, vol.36
, pp. 5346-5352
-
-
Goldsteins, G.1
Andersson, K.2
Olofsson, A.3
Dacklin, I.4
Edvinsson, A.5
Baranov, V.6
-
12
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227:680-5.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
13
-
-
0035955603
-
Capture of a dimeric intermediate during transthyretin amyloid formation
-
Olofsson A, Ippel HJ, Baranov V, Horstedt P, Wijmenga S, Lundgren E. Capture of a dimeric intermediate during transthyretin amyloid formation. J Biol Chem 2001; 276:39592-9.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39592-39599
-
-
Olofsson, A.1
Ippel, H.J.2
Baranov, V.3
Horstedt, P.4
Wijmenga, S.5
Lundgren, E.6
-
14
-
-
0027191973
-
Apoptosis mediated neurotoxicity induced by chronic application of beta amyloid fragment 25-35
-
Forloni G, Chiesa R, Smiroldo S, Verga L, Salmona M, Tagliavini F, et al. Apoptosis mediated neurotoxicity induced by chronic application of beta amyloid fragment 25-35. Neuroreport 1993; 4:523-6.
-
(1993)
Neuroreport
, vol.4
, pp. 523-526
-
-
Forloni, G.1
Chiesa, R.2
Smiroldo, S.3
Verga, L.4
Salmona, M.5
Tagliavini, F.6
-
16
-
-
0037022563
-
Natural beta-sheet proteins use negative design to avoid edge-to-edge aggregation
-
Richardson JS, Richardson DC. Natural beta-sheet proteins use negative design to avoid edge-to-edge aggregation. Proc Natl Acad Sci USA 2002; 99:2754-9.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 2754-2759
-
-
Richardson, J.S.1
Richardson, D.C.2
-
17
-
-
0029981197
-
Alternative conformations of amyloidogenic proteins govern their behavior
-
Kelly JW. Alternative conformations of amyloidogenic proteins govern their behavior. Curr Opin Struct Biol 1996; 6:11-7.
-
(1996)
Curr. Opin. Struct. Biol.
, vol.6
, pp. 11-17
-
-
Kelly, J.W.1
-
19
-
-
0027006436
-
Amyloid fibril formation requires a chemically discriminating nucleation event: Studies of an amyloidogenic sequence from the bacterial protein OsmB
-
Jarrett JT, Lansbury PT Jr. Amyloid fibril formation requires a chemically discriminating nucleation event: studies of an amyloidogenic sequence from the bacterial protein OsmB. Biochemistry 1992; 31:12345-52.
-
(1992)
Biochemistry
, vol.31
, pp. 12345-12352
-
-
Jarrett, J.T.1
Lansbury P.T., Jr.2
-
20
-
-
0027258525
-
The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
-
Jarrett JT, Berger EP, Lansbury PT Jr. The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry 1993; 32:4693-7.
-
(1993)
Biochemistry
, vol.32
, pp. 4693-4697
-
-
Jarrett, J.T.1
Berger, E.P.2
Lansbury P.T., Jr.3
-
21
-
-
0034730203
-
Designed protein tetramer zipped together with a hydrophobic Alzheimer homology: A structural clue to amyloid assembly
-
Otzen DE, Kristensen O, Oliveberg M. Designed protein tetramer zipped together with a hydrophobic Alzheimer homology: a structural clue to amyloid assembly. Proc Natl Acad Sci USA 2000; 97:9907-12.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 9907-9912
-
-
Otzen, D.E.1
Kristensen, O.2
Oliveberg, M.3
-
22
-
-
0034700129
-
Multiple quantum solid-state NMR indicates a parallel, not antiparallel, organization of beta-sheets in Alzheimer's beta-amyloid fibrils
-
Antzutkin ON, Balbach JJ, Leapman RD, Rizzo NW, Reed J, Tycko R. Multiple quantum solid-state NMR indicates a parallel, not antiparallel, organization of beta-sheets in Alzheimer's beta-amyloid fibrils. Proc Natl Acad Sci USA 2000; 97:13045-50.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13045-13050
-
-
Antzutkin, O.N.1
Balbach, J.J.2
Leapman, R.D.3
Rizzo, N.W.4
Reed, J.5
Tycko, R.6
-
23
-
-
0028804827
-
Structural model for the beta-amyloid fibril based on interstrand alignment of an antiparallel-sheet comprising a C-terminal peptide
-
Lansbury PT Jr, Costa PR, Griffiths JM, Simon EJ, Auger M, Halverson KJ, et al. Structural model for the beta-amyloid fibril based on interstrand alignment of an antiparallel-sheet comprising a C-terminal peptide. Nat Struct Biol 1995; 2:990-8.
-
(1995)
Nat. Struct. Biol.
, vol.2
, pp. 990-998
-
-
Lansbury P.T., Jr.1
Costa, P.R.2
Griffiths, J.M.3
Simon, E.J.4
Auger, M.5
Halverson, K.J.6
-
24
-
-
0037173120
-
Probing solvent accessibility of amyloid fibrils by solution NMR spectroscopy
-
Ippel JH, Olofsson A, Schleucher J, Lundgren E, Wijmenga SS. Probing solvent accessibility of amyloid fibrils by solution NMR spectroscopy. Proc Natl Acad Sci USA 2002; 99:8648-53.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8648-8653
-
-
Ippel, J.H.1
Olofsson, A.2
Schleucher, J.3
Lundgren, E.4
Wijmenga, S.S.5
-
25
-
-
0036242430
-
Mapping the core of the beta(2)-microglobulin amyloid fibril by H/D exchange
-
Hoshino M, Katou H, Hagihara Y, Hasegawa K, Naiki H, Goto Y. Mapping the core of the beta(2)-microglobulin amyloid fibril by H/D exchange. Nat Struct Biol 2002; 9:332-6.
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 332-336
-
-
Hoshino, M.1
Katou, H.2
Hagihara, Y.3
Hasegawa, K.4
Naiki, H.5
Goto, Y.6
-
26
-
-
0032447486
-
Ultrastructure of familial amyloid polyneuropathy amyloid fibrils: Examination with high-resolution electron microscopy
-
Inoue S, Kuroiwa M, Saraiva MJ, Guimaraes A, Kisilevsky R. Ultrastructure of familial amyloid polyneuropathy amyloid fibrils: examination with high-resolution electron microscopy. J Struct Biol 1998; 124:1-12.
-
(1998)
J. Struct. Biol.
, vol.124
, pp. 1-12
-
-
Inoue, S.1
Kuroiwa, M.2
Saraiva, M.J.3
Guimaraes, A.4
Kisilevsky, R.5
-
27
-
-
0028982292
-
Self-association of beta-amyloid peptide (1-40) in solution and binding to lipid membranes
-
Terzi E, Holzemann G, Seelig J. Self-association of beta-amyloid peptide (1-40) in solution and binding to lipid membranes. J Mol Biol 1995; 252:633-42.
-
(1995)
J. Mol. Biol.
, vol.252
, pp. 633-642
-
-
Terzi, E.1
Holzemann, G.2
Seelig, J.3
-
28
-
-
0035478665
-
Familial amyloid polyneuropathy: Receptor for advanced glycation end products-dependent triggering of neuronal inflammatory and apoptotic pathways
-
Sousa MM, Du Yan S, Fernandes R, Guimaraes A, Stern D, Saraiva MJ. Familial amyloid polyneuropathy: receptor for advanced glycation end products-dependent triggering of neuronal inflammatory and apoptotic pathways. J Neurosci 2001; 21:7576-86.
-
(2001)
J. Neurosci.
, vol.21
, pp. 7576-7586
-
-
Sousa, M.M.1
Du Yan, S.2
Fernandes, R.3
Guimaraes, A.4
Stern, D.5
Saraiva, M.J.6
|