Ultrastructure of familial amyloid polyneuropathy amyloid fibrils: Examination with high-resolution electron microscopy

Journal of Structural Biology

Volumn 124, Issue 1, 1998, Pages 1-12

  Inoue, Sadayuki ^a   Kuroiwa, Mie ^a   Saraiva, Maria J ^b   Guimarães, António ^b   Kisilevsky, Robert ^c  

^a MCGILL UNIVERSITY   (Canada)

^b HOSPITAL DE SANTO ANTÓNIO   (Portugal)

^c QUEEN S UNIVERSITY   (Canada)

Author keywords

Amyloid; Amyloid fibrils; Electron microscopy; Familial amyloid polyneuropathy; Immunolabeling; Ultrastructure

Indexed keywords

AMYLOID;

AMYLOID NEUROPATHY; ANTIBODY LABELING; ARTICLE; ELECTRON MICROSCOPY; HUMAN; HUMAN TISSUE; NERVE BIOPSY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DETERMINATION; STRUCTURE ANALYSIS; SURAL NERVE;

EID: 0032447486     PISSN: 10478477     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsbi.1998.4052     Document Type: Article

References (27)

1. Adams, D., and Said, G. (1996) Ultrastructural immunolabeling of amyloid fibrils in acquired and hereditary amyloid neuropathies, J. Neurol. 243, 63-67.
2. Andrade, C. (1952) A peculiar form of peripheral neuropathy: Familial atypical generalized amyloidosis with special involvement of the peripheral nerves, Brain 75, 408-427.
3. Bendayan, M., and Zollinger, M. (1983) Ultrastructural localization of antigenic sites on osmium-fixed tissues applying the protein A-gold technique, J. Histochem. Cytochem. 31, 101-109.
4. Benson, M. D., and Uemichi, T. (1996) Transthyretin amyloidosis, Amyoid 3, 44-56.
5. Blake, C., and Serpell, L. (1996) Synchrotron X-ray studies suggest that the core of the transthyretin amyloid fibrils is a continuous β-sheet helix, Structure 4, 989-998.
6. Blake, C. C. F., Geisow, J. J., Oatley, S. J., Rerat, B., and Rerat, C. (1978) Structure of prealbumin: Secondary, tertiary and quaternary interactions determined by Fourier refinement at 1.8 Å, J. Mol. Biol. 121, 339-356.
7. Botto, M., Hawkins, P. N., Bickerstaff, M. C. M., Herbert, J., Bygrave, A. E., McBride, A., Hutchinson, W. L., Tenent, G. A., Walport, M. J., and Pepys, M. B. (1997) Amyloid deposition is delayed in mice with targeted deletion of the serum amyloid P component gene, Nature Med. 3, 855-859.
8. Christensen, H. E. (1968) Improved histochemical staining techniques for mucopolysaccharides applied to experimental and human amyloids, in Mandema, E., Ruinen, L., Scholten, J. H., and Cohen, A. S. (Eds.), Amyloidosis, pp. 235-248, Excerpta Medica Found., Amsterdam.
9. Coimbra, A., and Andrade, C. (1971) Familial amyloid polyneuropathy: An electron microscope study of the peripheral nerve in five cases. I. Interstitial changes, Brain 94, 199-206.
10. Colon, W., and Kelly, J. W. (1992) Partial denaturation of transthyretin is sufficient for amyloid fibril formation in vitro, Biochemistry 31, 8654-8660.
11. Damas, A., Sebastiao, M. P., Domingues, F. S., Costa, P. P., and Saraiva, M. J. (1995) Structural studies on FAP fibrils: Removal of contaminants is essential for the interpretation of X-ray data, Amyloid 2, 173-178.
12. Inoue, S. (1991) Pentosome - a new connective tissue component - is a subunit of amyloid P, Cell Tissue Res. 263, 431-438.
13. Inoue, S. (1995a) Ultrastructural organization of connective tissue microfibrils in the posterior chamber of the eye in vivo and in vitro, Cell Tissue Res. 279, 291-302.
14. Inoue, S. (1995b) Ultrastructural and immunohistochemical studies of microfibril-associated components in the posterior chamber of the eye, Cell Tissue Res. 279, 303-313.
15. Inoue, S., and Kisilevsky, R. (1996) A high resolution ultrastructural study of experimental murine AA amyloid, Lab. Invest. 74, 670-683.
16. Inoue, S., Grant, D., and Leblond, C. P. (1989) Heparan sulfate proteoglycan is present in basement membrane as a double-tracked structure, J. Histochem. Cytochem. 37, 597-602.
17. 2-microglobulin amyloid fibrils, Kidney Int. 52, 1543-1549.
18. Inoue, S., Kuroiwa, M., Tan, R., and Kisilevsky, R. (1998) A high resolution ultrastructural comparison of isolated and in-situ murine AA amyloid fibrils, Amyloid Int. J. Exp. Clin. Invest. 5, 99-110.
19. Kelly, J. W., and Lansbury, P. T. (1994) A chemical approach to elucidate the mechanism of transthyretin and β-protein amyloid fibril formation, Amyloid Int. J. Exp. Clin. Invest. 1, 186-205.
20. Kirschner, D., Abraham, C., and Selkoe, D. (1986) X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibres in Alzheimer's disease indicates cross-β conformation, Proc. Natl. Acad. Sci. USA 83, 503-507.
21. Miroy, G. J., Lai, Z. H., Lashuel, H. A., Peterson, S. A., Strang, C., and Kelly, J. W. (1996) Inhibiting transthyretin amyloid fibril formation via protein stabilization, Proc. Natl. Acad. Sci. USA 93, 15051-15056.
22. Saraiva, M. J. M. (1991) Recent advances in the molecular pathology of familial amyloid polyneuropathy, Neuromusc. Disord. 1, 3-6.
23. Saraiva, M. J. M. (1995) Transthyretin mutations in health and disease, Hum. Mutat. 5, 191-196.
24. Saraiva, M. J. M., Birken, S., Costa, P. P., and Goodman, D. S. (1984) Amyloid fibril protein in familial amyloidotic polyneuropathy, Portuguese type: Definition of molecular abnormality in transthyretin (prealbumin), J. Clin. Invest. 74, 104-119.
25. Serpell, L. C., Sunde, M., Fraser, P. E., Luther, P. K., Morris, E. P., Sangren, O., Lundgren, E., and Blake, C. C. F. (1995) Examination of the structure of the transthyretin amyloid fibril by image reconstruction from electron micrographs, J. Mol. Biol. 254, 113-118.
26. Staunton, H. (1991) Familial amyloid polyneuropathies, Handb. Clin. Neurol. 60, 89-115.
27. Toyooka, K., Fujimura, H., Ueno, S., Yoshikawa, H., Kaido, M., Nishimura, T., Yorifuji, S., and Yanagihara, T. (1995) Familial amyloid polyneuropathy associated with transthyretin GLY42 mutation: A quantitative light and electron microscopic study of the peripheral nervous system, Acta Neuropathol. 90, 516-525.