Gastrointestinal tolerability of metamizol, acetaminophen, and diclofenac in subchronic treatment in rats

Digestive Diseases and Sciences

Volumn 47, Issue 12, 2002, Pages 2791-2798

  Sánchez, Susana ^a   De la Lastra, Catalina Alarcón ^a   Ortiz, Pablo ^b   Motilva, Virginia ^a   Martín, M José ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

^b Boehringer Ingelheim Group   (Spain)

Author keywords

Acetaminophen; Analgesic drugs; Cyclooxygenase; Diclofenac; Gastrointestinal injury; Metamizol; Western blot

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DICLOFENAC; DIPYRONE; GAMMA GLUTAMYLTRANSFERASE; HEMOGLOBIN; MYELOPEROXIDASE; PARACETAMOL; PROSTAGLANDIN SYNTHASE INHIBITOR;

ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; CONTROLLED STUDY; DRUG EFFECT; DRUG SAFETY; DRUG TOLERABILITY; ENZYME ACTIVITY; FEMALE; HEMATOCRIT; INTESTINE INJURY; INTESTINE MUCOSA; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; LIVER FUNCTION; MALE; MEAN CORPUSCULAR VOLUME; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STOMACH INJURY; STOMACH MUCOSA; THROMBOCYTE COUNT;

ACETAMINOPHEN; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIGENS, CD13; CYCLOOXYGENASE INHIBITORS; DICLOFENAC; DIPYRONE; FEMALE; GASTRIC MUCIN; MALE; PEROXIDASE; RATS; RATS, WISTAR;

EID: 0036907351     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021077810548     Document Type: Article

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