-
1
-
-
0015237292
-
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
-
Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature New Biol 1971;231:232-9.
-
(1971)
Nature New Biol
, vol.231
, pp. 232-239
-
-
Vane, J.R.1
-
2
-
-
0015207999
-
Effect of cyclic AMP on release of lysosomal enzymes from phagocytes
-
Weissmann G, Dukar P, Zurier RB. Effect of cyclic AMP on release of lysosomal enzymes from phagocytes. Nature New Biol 1971;231:131-5.
-
(1971)
Nature New Biol
, vol.231
, pp. 131-135
-
-
Weissmann, G.1
Dukar, P.2
Zurier, R.B.3
-
3
-
-
0025961094
-
Aspirin
-
Weissmann G. Aspirin. Sci Am 1991;264:84-90.
-
(1991)
Sci Am
, vol.264
, pp. 84-90
-
-
Weissmann, G.1
-
4
-
-
0028323295
-
Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation
-
Vane JR, Mitchell JA, Appleton I, et al. Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. Proc Natl Acad Sci USA 1994;91:2046-50.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 2046-2050
-
-
Vane, J.R.1
Mitchell, J.A.2
Appleton, I.3
-
5
-
-
0027944075
-
Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain
-
Seibert K, Zhang Y, Leahy K, et al. Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain. Proc Natl Acad Sci USA 1994; 91:12013-7.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12013-12017
-
-
Seibert, K.1
Zhang, Y.2
Leahy, K.3
-
6
-
-
0025248570
-
The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxide synthases
-
De Witt DL, el Harith EA, Kraemer SA, et al. The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxide synthases. J Biol Chem 1990;265:5192-8.
-
(1990)
J Biol Chem
, vol.265
, pp. 5192-5198
-
-
De Witt, D.L.1
El Harith, E.A.2
Kraemer, S.A.3
-
7
-
-
0030461132
-
Structural basis for selective inhibition of cyclo-oxygenase-2 by anti-inflammatory agents
-
Kurumbail RG, Stevens AM, Gierse JK, et al. Structural basis for selective inhibition of cyclo-oxygenase-2 by anti-inflammatory agents. Nature 1996;384:644-8.
-
(1996)
Nature
, vol.384
, pp. 644-648
-
-
Kurumbail, R.G.1
Stevens, A.M.2
Gierse, J.K.3
-
8
-
-
0029882063
-
Selective inhibition of human cyclo-oxygenase-2 by meloxicam
-
Churchill L, Graham AG, Shih C-K, Pauletti D, Farina PR, Grob PM. Selective inhibition of human cyclo-oxygenase-2 by meloxicam. Inflammopharmacology 1996;4:125-35.
-
(1996)
Inflammopharmacology
, vol.4
, pp. 125-135
-
-
Churchill, L.1
Graham, A.G.2
Shih, C.-K.3
Pauletti, D.4
Farina, P.R.5
Grob, P.M.6
-
9
-
-
0028327671
-
Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs
-
Rodriguez LAG, Jick H. Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs. Lancet 1994;343:769-72.
-
(1994)
Lancet
, vol.343
, pp. 769-772
-
-
Rodriguez, L.A.G.1
Jick, H.2
-
10
-
-
0028353941
-
Risks of bleeding peptic ulcer associated with individual non-steroidal antiinflammatory drugs
-
Langman MJS, Weil J, Wainwright P, et al. Risks of bleeding peptic ulcer associated with individual non-steroidal antiinflammatory drugs. Lancet 1994;43:1075-8.
-
(1994)
Lancet
, vol.43
, pp. 1075-1078
-
-
Langman, M.J.S.1
Weil, J.2
Wainwright, P.3
-
11
-
-
0026498268
-
The gastroduodenal safety and efficacy of the fixed combination of diclofenac and misoprostol in the treatment of osteoarthritis
-
Bolten BW, Melo Gomes JA, Stead H, Geis GS. The gastroduodenal safety and efficacy of the fixed combination of diclofenac and misoprostol in the treatment of osteoarthritis. Br J Rheumatol 1992;31:753-8.
-
(1992)
Br J Rheumatol
, vol.31
, pp. 753-758
-
-
Bolten, B.W.1
Melo Gomes, J.A.2
Stead, H.3
Geis, G.S.4
-
12
-
-
0026590223
-
A double-blind comparison of the gastroduodenal safety and efficacy of diclofenac and a fixed dose combination of diclofenac and misoprostol in the treatment of rheumatoid arthritis
-
Verdickt W, Moran C, Hantzschel H, Fraga AM, Stead H, Geis GS. A double-blind comparison of the gastroduodenal safety and efficacy of diclofenac and a fixed dose combination of diclofenac and misoprostol in the treatment of rheumatoid arthritis. Scand J Rheumatol 1992;21:85-91.
-
(1992)
Scand J Rheumatol
, vol.21
, pp. 85-91
-
-
Verdickt, W.1
Moran, C.2
Hantzschel, H.3
Fraga, A.M.4
Stead, H.5
Geis, G.S.6
-
13
-
-
0027732735
-
Double-blind comparison of efficacy and gastroduodenal safety of diclofenac/misoprostol, piroxicam and naproxen in the treatment of osteoarthritis
-
Mel Gomes JA, Roth SH, Zéeh J,Bruyn GAW, Woods EM, Geis GS. Double-blind comparison of efficacy and gastroduodenal safety of diclofenac/misoprostol, piroxicam and naproxen in the treatment of osteoarthritis. Ann Rheum Dis 1993;52:881-5.
-
(1993)
Ann Rheum Dis
, vol.52
, pp. 881-885
-
-
Mel Gomes, J.A.1
Roth, S.H.2
Zéeh, J.3
Bruyn, G.A.W.4
Woods, E.M.5
Geis, G.S.6
-
14
-
-
0009630629
-
Diclofenac/misoprostol and indomethacin: Efficacy and GI damage in rheumatoid arthritis and ankylosing spondylitis
-
McKenna F, Allan L, Kiff PS. Diclofenac/misoprostol and indomethacin: efficacy and GI damage in rheumatoid arthritis and ankylosing spondylitis [abstract]. Rheumatol Eur 1995;24 Suppl 3:D15.
-
(1995)
Rheumatol Eur
, vol.24
, Issue.3 SUPPL.
-
-
McKenna, F.1
Allan, L.2
Kiff, P.S.3
-
15
-
-
26144452582
-
The combination drug diclofenac 75 mg/misoprostol 200 mcg provides equivalent anti-arthritic efficacy to diclofenac 75 mg SR in RA and OA but with an improved GI safety profile
-
Stead H, Morant SV, Shield MJ. The combination drug diclofenac 75 mg/misoprostol 200 mcg provides equivalent anti-arthritic efficacy to diclofenac 75 mg SR in RA and OA but with an improved GI safety profile [abstract]. Rheumatol Eur 1996;25 Suppl:A95.
-
(1996)
Rheumatol Eur
, vol.25
, Issue.SUPPL.
-
-
Stead, H.1
Morant, S.V.2
Shield, M.J.3
-
16
-
-
26144464161
-
Fixed combination of diclofenac and misoprostol in rheumatoid arthritis
-
Bocanegra TS, Ball J, Hurley S, Geis GS, Wallemark C. Fixed combination of diclofenac and misoprostol in rheumatoid arthritis [abstract]. Rheumatol Eur 1996;25 Suppl:A97.
-
(1996)
Rheumatol Eur
, vol.25
, Issue.SUPPL.
-
-
Bocanegra, T.S.1
Ball, J.2
Hurley, S.3
Geis, G.S.4
Wallemark, C.5
-
17
-
-
26144460584
-
Fixed combination of diclofenac/misoprostol in treatment of osteoarthritis
-
Bocanegra TS, Ball J, Geis GS, Wallemark C. Fixed combination of diclofenac/misoprostol in treatment of osteoarthritis [abstract]. Rheumatol Eur 1996;25 Suppl:A358.
-
(1996)
Rheumatol Eur
, vol.25
, Issue.SUPPL.
-
-
Bocanegra, T.S.1
Ball, J.2
Geis, G.S.3
Wallemark, C.4
-
18
-
-
84960597358
-
Efficacy and gastroduodenal safety of a fixed combination of diclofenac and misoprostol in the treatment of arthritis
-
McKenna F. Efficacy and gastroduodenal safety of a fixed combination of diclofenac and misoprostol in the treatment of arthritis. Br J Rheumatol 1995;34 Suppl 1:11-8.
-
(1995)
Br J Rheumatol
, vol.34
, Issue.1 SUPPL.
, pp. 11-18
-
-
McKenna, F.1
-
19
-
-
0026080987
-
Enteroscopic diagnosis of small bowel ulceration in patients receiving non-steroidal anti-inflammatory drugs
-
Morris AJ, Madhok R, Sturrock RD, Madhok R, Capell HA, MacKenzie JF. Enteroscopic diagnosis of small bowel ulceration in patients receiving non-steroidal anti-inflammatory drugs. Lancet 1991;337:520.
-
(1991)
Lancet
, vol.337
, pp. 520
-
-
Morris, A.J.1
Madhok, R.2
Sturrock, R.D.3
Madhok, R.4
Capell, H.A.5
MacKenzie, J.F.6
-
20
-
-
0028338431
-
The effect of misoprostol on the anaemia of NSAID enteropathy
-
Morris AJ, Murray L, Sturrock RD, Madhok R, Capell HA, MacKenzie JF. The effect of misoprostol on the anaemia of NSAID enteropathy. Aliment Pharmacol Ther 1994;8:343-6.
-
(1994)
Aliment Pharmacol Ther
, vol.8
, pp. 343-346
-
-
Morris, A.J.1
Murray, L.2
Sturrock, R.D.3
Madhok, R.4
Capell, H.A.5
MacKenzie, J.F.6
-
21
-
-
0028649470
-
Arthrotec, diclofenac and ibuprofen in general practice
-
Kiff PS, Stead H, Morant SV, Shield MJ. Arthrotec, diclofenac and ibuprofen in general practice. Eur J Rheumatol 1994;14 Suppl 3: 31-8.
-
(1994)
Eur J Rheumatol
, vol.14
, Issue.3 SUPPL.
, pp. 31-38
-
-
Kiff, P.S.1
Stead, H.2
Morant, S.V.3
Shield, M.J.4
-
23
-
-
0026969308
-
Prostaglandins as modulators rather than mediators of inflammation
-
Weissmann G. Prostaglandins as modulators rather than mediators of inflammation. J Lipid Med 1993;6:275-86.
-
(1993)
J Lipid Med
, vol.6
, pp. 275-286
-
-
Weissmann, G.1
-
24
-
-
0026466675
-
Misoprostol: New frontiers: benefits beyond the gastrointestinal tract
-
Shield MJ. Misoprostol: new frontiers: benefits beyond the gastrointestinal tract. Scand J Rheumatol 1992;92 Suppl:31-52.
-
(1992)
Scand J Rheumatol
, vol.92
, Issue.SUPPL.
, pp. 31-52
-
-
Shield, M.J.1
-
25
-
-
0028938530
-
Novel applications of misoprostol
-
Shield MJ. Novel applications of misoprostol. Pharmacol Ther 1995;65:125-47.
-
(1995)
Pharmacol Ther
, vol.65
, pp. 125-147
-
-
Shield, M.J.1
-
26
-
-
2642709864
-
Effects of the prostaglandin analogue misoprostol on inflammatory mediator release by human monocytes
-
Widomski DL, Walsh RE, Baron DA, Hidvegi MI, Fretland DJ, Collins PW. Effects of the prostaglandin analogue misoprostol on inflammatory mediator release by human monocytes. Agents Actions 1992;4:3-31.
-
(1992)
Agents Actions
, vol.4
, pp. 3-31
-
-
Widomski, D.L.1
Walsh, R.E.2
Baron, D.A.3
Hidvegi, M.I.4
Fretland, D.J.5
Collins, P.W.6
-
27
-
-
2642672627
-
1 analog misoprostol reduces renal ischemic injury
-
1 analog misoprostol reduces renal ischemic injury [abstract]. Kidney Int 1989;35:415.
-
(1989)
Kidney Int
, vol.35
, pp. 415
-
-
Paller, M.S.1
-
28
-
-
2642648480
-
Effect of misoprostol on histamine secretion from isolated rat and human mast cells and basophils
-
Shah PM, Pearce FL. Effect of misoprostol on histamine secretion from isolated rat and human mast cells and basophils. Am J Ther 1995;2:169-72.
-
(1995)
Am J Ther
, vol.2
, pp. 169-172
-
-
Shah, P.M.1
Pearce, F.L.2
-
29
-
-
0025763326
-
The sensitivity of synthesis of human cartilage matrix to inhibition by IL-2 suggests a mechanism for the development of osteoarthritis
-
Dingle JT, Horner A, Shield MJ. The sensitivity of synthesis of human cartilage matrix to inhibition by IL-2 suggests a mechanism for the development of osteoarthritis. Cell Biochem Funct 1991;9:99-102.
-
(1991)
Cell Biochem Funct
, vol.9
, pp. 99-102
-
-
Dingle, J.T.1
Horner, A.2
Shield, M.J.3
-
30
-
-
0029962084
-
Costimulatory effects of misoprostol and diclofenac on glycosaminoglycan synthesis in human cartilage explants and their therapeutic relevance
-
Shield MJ, Dingle JT. Costimulatory effects of misoprostol and diclofenac on glycosaminoglycan synthesis in human cartilage explants and their therapeutic relevance. Am J Ther 1996; 3: 195-203.
-
(1996)
Am J Ther
, vol.3
, pp. 195-203
-
-
Shield, M.J.1
Dingle, J.T.2
-
31
-
-
0030030495
-
Misoprostol inhibits polymethylmethacrylate-stimulated lysosomal degranulation and IL-1 release from neutrophils
-
Papatheofanis FJ, Barmada R. Misoprostol inhibits polymethylmethacrylate-stimulated lysosomal degranulation and IL-1 release from neutrophils. Am J Ther 1996;3:21-6.
-
(1996)
Am J Ther
, vol.3
, pp. 21-26
-
-
Papatheofanis, F.J.1
Barmada, R.2
-
33
-
-
0029077616
-
Trigeminal neuralgia in multiple sclerosis relieved by a prostaglandin e analogue
-
Reder AT, Arnason BGW. Trigeminal neuralgia in multiple sclerosis relieved by a prostaglandin E analogue. Neurology 1995;45: 1097-100.
-
(1995)
Neurology
, vol.45
, pp. 1097-1100
-
-
Reder, A.T.1
Arnason, B.G.W.2
-
34
-
-
0026043126
-
Effect of misoprostol on combinations of prostaglandins in synovial fluid
-
Doube A, Davies J, Notariani L, Holgate K, Fenn GC. Effect of misoprostol on combinations of prostaglandins in synovial fluid. Ann Rheum Dis 1991;50:797-9.
-
(1991)
Ann Rheum Dis
, vol.50
, pp. 797-799
-
-
Doube, A.1
Davies, J.2
Notariani, L.3
Holgate, K.4
Fenn, G.C.5
-
35
-
-
8944233869
-
The analgesic interaction of misoprostol with NSAID
-
Cooper SA, Cowan A, Tallarida RJ, et al. The analgesic interaction of misoprostol with NSAID. Am J Ther 1996;3:261-7.
-
(1996)
Am J Ther
, vol.3
, pp. 261-267
-
-
Cooper, S.A.1
Cowan, A.2
Tallarida, R.J.3
-
36
-
-
0006561211
-
An evaluation of diclofenac-misoprostol combinations in post-operative oral surgery pain
-
Forbes JA, Beaver WT. An evaluation of diclofenac-misoprostol combinations in post-operative oral surgery pain [abstract]. Clin Pharmacol Ther 1994;55:126.
-
(1994)
Clin Pharmacol Ther
, vol.55
, pp. 126
-
-
Forbes, J.A.1
Beaver, W.T.2
-
37
-
-
26144458457
-
Analgesic activity of a fixed combination of diclofenac plus misoprostol in dental pain
-
Mehlisch DR, Bocanegra TS, Callison D, Wallemark C. Analgesic activity of a fixed combination of diclofenac plus misoprostol in dental pain [abstract]. Rheumatol Eur 1996; 25 Suppl 1:A449.
-
(1996)
Rheumatol Eur
, vol.25
, Issue.1 SUPPL.
-
-
Mehlisch, D.R.1
Bocanegra, T.S.2
Callison, D.3
Wallemark, C.4
-
38
-
-
0031038042
-
A continuous patient activity monitor: Validation and relation to disability
-
Walker DJ, Heslop PS, Plummer CJ, Essex T, Chandler S. A continuous patient activity monitor: validation and relation to disability. Physiol Meas 1997;18:49-59.
-
(1997)
Physiol Meas
, vol.18
, pp. 49-59
-
-
Walker, D.J.1
Heslop, P.S.2
Plummer, C.J.3
Essex, T.4
Chandler, S.5
-
39
-
-
0345145522
-
Patient activity as an objective measure of NSAID therapy: An Arthrotec and NUMACT study
-
Walker DJ, Chandler C, Essex T, Heslop P, Stead H. Patient activity as an objective measure of NSAID therapy: an Arthrotec and NUMACT study [abstract]. Br J Rheumatol 1995;34 Suppl 2:A24.
-
(1995)
Br J Rheumatol
, vol.34
, Issue.2 SUPPL.
-
-
Walker, D.J.1
Chandler, C.2
Essex, T.3
Heslop, P.4
Stead, H.5
-
40
-
-
2642680637
-
Comparison of effect of Arthrotec 75 and diclofenac 75 mg SR on patient activity using the NUMACT activity monitor
-
Walker DJ, Heslop PS, Chandler C, Morant SV, Kiff PK, Stead H. Comparison of effect of Arthrotec 75 and diclofenac 75 mg SR on patient activity using the NUMACT activity monitor [abstract]. Br J Rheumatol 1996;35 Suppl 2:33.
-
(1996)
Br J Rheumatol
, vol.35
, Issue.2 SUPPL.
, pp. 33
-
-
Walker, D.J.1
Heslop, P.S.2
Chandler, C.3
Morant, S.V.4
Kiff, P.K.5
Stead, H.6
-
41
-
-
0023612398
-
Circulating hyaluronic acid levels vary with physical activity in healthy subjects and in rheumatoid arthritis patients - Relationship to synovitis mass and morning stiffness
-
Engström-Laurent A, Hällgren R. Circulating hyaluronic acid levels vary with physical activity in healthy subjects and in rheumatoid arthritis patients - relationship to synovitis mass and morning stiffness. Arthritis Rheum 1987;30:1333-8.
-
(1987)
Arthritis Rheum
, vol.30
, pp. 1333-1338
-
-
Engström-Laurent, A.1
Hällgren, R.2
|