메뉴 건너뛰기




Volumn 45, Issue 2, 1996, Pages 83-88

Role of endogenous sulphydryls and neutrophil infiltration in the pathogenesis of gastric mucosal injury induced by piroxicam in rats

Author keywords

Gastric ulcer; Neutrophils; NSAIDs; Piroxicam; Sulphydryl compounds

Indexed keywords

MYELOPEROXIDASE; NONSTEROID ANTIINFLAMMATORY AGENT; PIROXICAM; THIOL DERIVATIVE;

EID: 0030020905     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02265120     Document Type: Article
Times cited : (84)

References (33)
  • 1
    • 0023697639 scopus 로고
    • Prevention of NSAID-induced gastric ulcer with misoprostol. Multicentre, double-blind, placebo-controlled trial
    • Graham DY, Agrawal NM, Roth SH. Prevention of NSAID-induced gastric ulcer with misoprostol. Multicentre, double-blind, placebo-controlled trial. Lancet 1988;2:1277-80.
    • (1988) Lancet , vol.2 , pp. 1277-1280
    • Graham, D.Y.1    Agrawal, N.M.2    Roth, S.H.3
  • 2
    • 0025108137 scopus 로고
    • Mechanism of gastroprotection
    • Konturek SJ. Mechanism of gastroprotection. Scand J Gastroenterol 1990;25 Suppl. 174:15-7.
    • (1990) Scand J Gastroenterol , vol.25 , Issue.174 SUPPL. , pp. 15-7
    • Konturek, S.J.1
  • 3
    • 0026742925 scopus 로고
    • Nonsteroidal anti-inflammatory drugs - The clinical dilemmas
    • McCarthy DM. Nonsteroidal anti-inflammatory drugs - the clinical dilemmas. Scand J Gastroenterol 1992;27 Suppl 174:9-12.
    • (1992) Scand J Gastroenterol , vol.27 , Issue.174 SUPPL. , pp. 9-12
    • McCarthy, D.M.1
  • 4
    • 0026674556 scopus 로고
    • Non-steroidal antiinflammatory drug gastropathy and cytoprotection: Pathogenesis and mechanisms re-examined
    • Wallace J. Non-steroidal antiinflammatory drug gastropathy and cytoprotection: pathogenesis and mechanisms re-examined. Scand J Gastroenterol 1992;22:3-8.
    • (1992) Scand J Gastroenterol , vol.22 , pp. 3-8
    • Wallace, J.1
  • 5
    • 0028049821 scopus 로고
    • Role of gastric blood flow, neutrophil infiltration in gastric adaptation to aspirin in the rat
    • Konturek SJ, Brzozowski T, Stachura J, Dembinski A, Malka J. Role of gastric blood flow, neutrophil infiltration in gastric adaptation to aspirin in the rat. Gut 1994;35:1189-96.
    • (1994) Gut , vol.35 , pp. 1189-1196
    • Konturek, S.J.1    Brzozowski, T.2    Stachura, J.3    Dembinski, A.4    Malka, J.5
  • 6
    • 0026986514 scopus 로고
    • Current concepts in gastric microcirculatory pathophysiology
    • Guth P. Current concepts in gastric microcirculatory pathophysiology. Yale J Biol Med 1992;65:677-88.
    • (1992) Yale J Biol Med , vol.65 , pp. 677-688
    • Guth, P.1
  • 7
    • 0026559465 scopus 로고
    • Circulatory mechanisms of gastric mucosal damage and protection
    • Jacobson ED. Circulatory mechanisms of gastric mucosal damage and protection. Gastroenterology 1994;102:1788-800.
    • (1994) Gastroenterology , vol.102 , pp. 1788-1800
    • Jacobson, E.D.1
  • 9
    • 0024591782 scopus 로고
    • Mechanisms of nonsteroidal-anti-inflammatory drugs-induced gastric damage
    • Shoen RT, Vender RJ. Mechanisms of nonsteroidal-anti-inflammatory drugs-induced gastric damage. Am J Med 1989;86:449-57.
    • (1989) Am J Med , vol.86 , pp. 449-457
    • Shoen, R.T.1    Vender, R.J.2
  • 10
    • 0343659901 scopus 로고
    • The biochemical pharmacology of sulphydryls compounds in gastric mucosal injury and protection
    • Szabo, S, Mózik G, editors New York: Elsevier
    • Szabo S, Pihan G, Dupuy D. The biochemical pharmacology of sulphydryls compounds in gastric mucosal injury and protection. In: Szabo, S, Mózik G, editors. New Pharmacology of Ulcer Disease. New York: Elsevier, 1987:424-46.
    • (1987) New Pharmacology of Ulcer Disease , pp. 424-446
    • Szabo, S.1    Pihan, G.2    Dupuy, D.3
  • 11
    • 0026062604 scopus 로고
    • Esculine. ranitidine and carbenoxolone: Different modes of action on gastric mucosa
    • Martin MJ, Marhuenda E, Alarcón de la Lastra C. Esculine. ranitidine and carbenoxolone: different modes of action on gastric mucosa. Gen Pharmac 1991;22:1001-4.
    • (1991) Gen Pharmac , vol.22 , pp. 1001-1004
    • Martin, M.J.1    Marhuenda, E.2    Alarcón De La Lastra, C.3
  • 13
    • 77049187161 scopus 로고
    • Methods for determination of hexosamines in tissues
    • Boas NF. Methods for determination of hexosamines in tissues. J Biol Chem 1953;204:553-66.
    • (1953) J Biol Chem , vol.204 , pp. 553-566
    • Boas, N.F.1
  • 14
    • 0025883326 scopus 로고
    • The role of gastric mucosal sulphydryls in the ulcer-protecting effects of sulphasalazine
    • Garg GP, Cho CH, Ogle CW. The role of gastric mucosal sulphydryls in the ulcer-protecting effects of sulphasalazine. J Pharm Pharmacol 1991;43:733-4.
    • (1991) J Pharm Pharmacol , vol.43 , pp. 733-734
    • Garg, G.P.1    Cho, C.H.2    Ogle, C.W.3
  • 15
    • 0014428865 scopus 로고
    • Stimulation of total protein-bound and non-protein sulphydryls groups in tissue with Ellman's reagent
    • Sedlak J, Lindsay RH. Stimulation of total protein-bound and non-protein sulphydryls groups in tissue with Ellman's reagent. Am Biochem 1968;25:192-205.
    • (1968) Am Biochem , vol.25 , pp. 192-205
    • Sedlak, J.1    Lindsay, R.H.2
  • 16
    • 0023627926 scopus 로고
    • 2 aggravates gastric mucosal injury induced by histamine in rats: Possible role of the increased mucosal vascular permeability
    • 2 aggravates gastric mucosal injury induced by histamine in rats: possible role of the increased mucosal vascular permeability. Gastroenterology 1987;93: 1276-88.
    • (1987) Gastroenterology , vol.93 , pp. 1276-1288
    • Takeuchi, K.1    Furukawa, O.2    Nishiwaki, H.3    Okabe, S.4
  • 17
    • 0014768365 scopus 로고
    • Simple method for quantification of enhanced vascular permeability
    • Ukada K, Takeuchi Y, Movat HZ. Simple method for quantification of enhanced vascular permeability. Proc Soc Exp Biol Med 1970;133:1276-88.
    • (1970) Proc Soc Exp Biol Med , vol.133 , pp. 1276-1288
    • Ukada, K.1    Takeuchi, Y.2    Movat, H.Z.3
  • 18
    • 0024999311 scopus 로고
    • Assessment of leukocyte in involvement during ischemia and reperfusion on the intestine
    • Packer L, Glazer AN, editors San Diego: Academic Press
    • Grisham MB, Beniot JN, Granger DN. Assessment of leukocyte in involvement during ischemia and reperfusion on the intestine. In: Packer L, Glazer AN, editors. Methods in enzymology. Oxygen radicals in biological systems. San Diego: Academic Press, 1990:729-41.
    • (1990) Methods in Enzymology. Oxygen Radicals in Biological Systems , pp. 729-741
    • Grisham, M.B.1    Beniot, J.N.2    Granger, D.N.3
  • 19
    • 0026527905 scopus 로고
    • Neutrophil accumulation in ischemic reperfused rat liver: Evidence for a role for superoxide free radicals
    • Komatsu H, Koo A, Ghadisham E, Zeng H, Kuhlenkamp F, Inouue M, et al. Neutrophil accumulation in ischemic reperfused rat liver: evidence for a role for superoxide free radicals. Am J Physiol 1992;262:G669-76.
    • (1992) Am J Physiol , vol.262
    • Komatsu, H.1    Koo, A.2    Ghadisham, E.3    Zeng, H.4    Kuhlenkamp, F.5    Inouue, M.6
  • 20
    • 0025856636 scopus 로고
    • Nonsteroidal anti-inflammatory drugs differences and similarities
    • Brooks PM, Day RO. Nonsteroidal anti-inflammatory drugs differences and similarities. N Engl J Med 1991;324:1716-25.
    • (1991) N Engl J Med , vol.324 , pp. 1716-1725
    • Brooks, P.M.1    Day, R.O.2
  • 21
    • 0026999207 scopus 로고
    • Expression of the murine prostaglandin (PGH) synthase-1 and PGH synthease-2-isoenzymes in cis-1 cells
    • Meade EA, Smith WL, Dewitt DL. Expression of the murine prostaglandin (PGH) synthase-1 and PGH synthease-2-isoenzymes in cis-1 cells. J Lipid Mediat 1993;6:119-29.
    • (1993) J Lipid Mediat , vol.6 , pp. 119-129
    • Meade, E.A.1    Smith, W.L.2    Dewitt, D.L.3
  • 22
    • 0027912932 scopus 로고
    • PGH synthase selectivity: The potential for safer nonsteroidal antiinflammatory drugs
    • Dewitt DL, Meade EA, Smith WL. PGH synthase selectivity: the potential for safer nonsteroidal antiinflammatory drugs. Am J Med 1993;95 suppl 2A:40S-4.
    • (1993) Am J Med , vol.95 , Issue.SUPPL. 2A
    • Dewitt, D.L.1    Meade, E.A.2    Smith, W.L.3
  • 23
    • 0025372335 scopus 로고
    • Experimental gastric and duodenal ulcers
    • Szabo S, Vattay P. Experimental gastric and duodenal ulcers. Gastroenterol Clin N Am 1990;19:67-85.
    • (1990) Gastroenterol Clin N Am , vol.19 , pp. 67-85
    • Szabo, S.1    Vattay, P.2
  • 24
    • 0025225730 scopus 로고
    • Role of epidermal growth factor, prostaglandin and sulphydryls in stress-induced gastric lesions
    • Konturek PK, Brzozowski T, Konturek SJ, Dembinski A. Role of epidermal growth factor, prostaglandin and sulphydryls in stress-induced gastric lesions. Gastroenterology 1990; 99:1607-15.
    • (1990) Gastroenterology , vol.99 , pp. 1607-1615
    • Konturek, P.K.1    Brzozowski, T.2    Konturek, S.J.3    Dembinski, A.4
  • 25
    • 0027322319 scopus 로고
    • Role of active oxygen, lipid peroxidation and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin in rats
    • Yoshikawa T, Naito Y, Tomii T, Kaneko T, Iinuma S, Ichikawa H, et al. Role of active oxygen, lipid peroxidation and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin in rats. Gut 1993;34:734-7.
    • (1993) Gut , vol.34 , pp. 734-737
    • Yoshikawa, T.1    Naito, Y.2    Tomii, T.3    Kaneko, T.4    Iinuma, S.5    Ichikawa, H.6
  • 26
    • 0025078185 scopus 로고
    • Gastric ulceration induced by non-steroidal antiinflammtory drugs is a neutrophil dependent process
    • Gastrointest Liver Physiol 22
    • Wallace JL, Kennan CM, Granger ON. Gastric ulceration induced by non-steroidal antiinflammtory drugs is a neutrophil dependent process. Am J Physiol 1990;259 (Gastrointest Liver Physiol 22):G462-7.
    • (1990) Am J Physiol , vol.259
    • Wallace, J.L.1    Kennan, C.M.2    Granger, O.N.3
  • 27
    • 0027093891 scopus 로고
    • Aspirin induced acute gastric mucosal injury is a neutrophil-dependent process in rats
    • Gastrointest Liver Physiol 16
    • Lee M, Aldred K, Lee E, Feldman M. Aspirin induced acute gastric mucosal injury is a neutrophil-dependent process in rats. Am J Physiol 1992;263 (Gastrointest Liver Physiol 16): G920-6.
    • (1992) Am J Physiol , vol.263
    • Lee, M.1    Aldred, K.2    Lee, E.3    Feldman, M.4
  • 28
    • 0026986514 scopus 로고
    • Current concepts in gastric microcirculatory pathophysiology
    • Guth PH. Current concepts in gastric microcirculatory pathophysiology. Y J Biol Med 1992;65:677-88.
    • (1992) Y J Biol Med , vol.65 , pp. 677-688
    • Guth, P.H.1
  • 29
    • 0025727507 scopus 로고
    • A monoclonal antibody against the CD18 leukocyte adhesion molecule prevents indomethacin-induced gastric damage in the rabbit
    • Wallace JL, Arfors KE, Mcknight GW. A monoclonal antibody against the CD18 leukocyte adhesion molecule prevents indomethacin-induced gastric damage in the rabbit. Gastroenterology 1991;100:878-83.
    • (1991) Gastroenterology , vol.100 , pp. 878-883
    • Wallace, J.L.1    Arfors, K.E.2    Mcknight, G.W.3
  • 30
    • 0028222381 scopus 로고
    • Effect of nonsteroidal anti-inflammatory drugs on LFA-1 and ICAM-1 expression in gastric mucosa
    • Andrews FJ, Malcontenti-Wilson C, O'Brien PE. Effect of nonsteroidal anti-inflammatory drugs on LFA-1 and ICAM-1 expression in gastric mucosa. Am J Physiol 1994;266:G657-664.
    • (1994) Am J Physiol , vol.266
    • Andrews, F.J.1    Malcontenti-Wilson, C.2    O'Brien, P.E.3
  • 31
    • 0021894607 scopus 로고
    • The mechanisms of antiinflammatory steroid action in allergic diseases
    • Scheimer RP. The mechanisms of antiinflammatory steroid action in allergic diseases. Ann Rev Pharmacol Toxicol 1985; 25:381-412.
    • (1985) Ann Rev Pharmacol Toxicol , vol.25 , pp. 381-412
    • Scheimer, R.P.1
  • 32
    • 0027478621 scopus 로고
    • Do infiltrating neutrophils contribute to the pathogenesis of indomethacin induced ulceration of the rat gastric antrum
    • Trevethick MA, Clayton NM, Strong P, Harman IW. Do infiltrating neutrophils contribute to the pathogenesis of indomethacin induced ulceration of the rat gastric antrum: Gut 1993;34:156-60.
    • (1993) Gut , vol.34 , pp. 156-160
    • Trevethick, M.A.1    Clayton, N.M.2    Strong, P.3    Harman, I.W.4
  • 33
    • 0023632379 scopus 로고
    • Free radicals and lipid peroxidation in ethanol or aspirin-induced gastric mucosal injury
    • Pihan G, Regillo C, Szabo S. Free radicals and lipid peroxidation in ethanol or aspirin-induced gastric mucosal injury. Dig Dis Sci 1987;32:1395-401.
    • (1987) Dig Dis Sci , vol.32 , pp. 1395-1401
    • Pihan, G.1    Regillo, C.2    Szabo, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.