Selection of small-molecule mediators of the RNA regulation of PKR, the RNA-dependent protein kinase

ChemBioChem

Volumn 3, Issue 9, 2002, Pages 859-865

  Carlson, Coby B ^a   Spanggord, Richard J ^a   Beal, Peter A ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

Antiviral agents; Bioorganic chemistry; Combinatorial chemistry; Peptides; RNA recognition

Indexed keywords

1 NAPHTHYLALANINE; ACRIDINE DERIVATIVE; DOUBLE STRANDED RNA; EDETIC ACID; HYDROXYPROLINE; INTERFERON; IRON BINDING PROTEIN; NAPHTHYL GROUP; RNA BINDING PROTEIN; RNA DEPENDENT PROTEIN KINASE; UNCLASSIFIED DRUG; VIRUS RNA;

ANTIVIRAL ACTIVITY; ARTICLE; COMPLEX FORMATION; ENZYME ACTIVATION; ENZYME INHIBITION; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; RNA BINDING; RNA CLEAVAGE; VIRUS REPLICATION;

ACRIDINES; ANTIVIRAL AGENTS; BINDING SITES; COMBINATORIAL CHEMISTRY TECHNIQUES; EIF-2 KINASE; ENZYME ACTIVATION; HUMANS; INHIBITORY CONCENTRATION 50; LIGANDS; PEPTIDES; RNA, DOUBLE-STRANDED; RNA, VIRAL; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036903526     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. C. G. Proud, Trends Biochem. Sci. 1995, 20, 241-246.
2. M. J. Clemens, A. Elia, J. Interferon Cytokine Res. 1997, 17, 503-24.
3. B. R. G. Williams, Oncogene 1999, 18, 6112-6120.
4. R. J. Kaufman, Proc. Natl. Acad. Sci. USA 1999, 96, 11693-11695.
5. L. Manche, S. R. Green, C. Schmedt, M. B. Mathews, Mol. Cell Biol. 1992, 12, 5238-5248.
6. B. W. Carpick, V. Graziano, D. Schneider, R. K. Maitra, X. Lee, B.R.G. Williams, J. Biol. Chem. 1997, 272, 9510-9516.
7. S. Wu, R. J. Kaufman, J. Biol. Chem. 1997, 272, 1291-1296.
8. K. M. Vattem, K. A. Staschke, R. C. Wek, Eur. J. Biochem. 2001, 268, 3674-3684.
9. M. G. Katze, M. Wambach, M. L. Wong, M. Garfinkel, E. Meurs, K. Chong, B. R. G. Williams, A. G. Hovanessian, G. N. Barber, Mol. Cell Biol. 1991, 11, 5497-5505.
10. C. DeHaro, R. Mendez, J. Santoyo, FASEB J. 1996, 10, 1378-1387.
11. M. J. Clemens, U. A. Bommer, Int. J. Biochem. Cell Biol. 1999, 31, 1-23.
12. J. Kitajewski, R. J. Schneider, B. Safer, S. M. Munemitsu, C. E. Samuel, B. Thimmappaya, T. Shenk, Cell 1986, 45, 195-200.
13. P. A. Clarke, N. A. Sharp, M. J. Clemens, Eur. J. Biochem. 1990, 193, 635-641.
14. T.V. Sharp, M. Schwemmle, I. Jeffrey, K. Laing, H. Mellor, C. G. Proud, K. Hilse, M.J. Clemens, Nucleic Acids Res. 1993, 21, 4483-4490.
15. I. Fierro-Monti, M. B. Mathews, Trends Biochem. Sci. 2000, 25, 241-246.
16. E. Meurs, K. Chong, J. Galabrun, N. S. B. Thomas, I. M. Kerr, B. R. G. Williams, A.G. Hovanessian, Cell 1990, 62, 379-390.
17. S. R Green, M. B. Mathews, Genes Dev. 1992, 6, 2478-2490.
18. B.L. Bass, K. Nishikura, W. Keller, P. H. Seeburg, R. B. Emeson, M. A. O'Connell, C. E. Samuel, A. Herbert, RNA 1997, 3, 947-949.
19. S. B. Lee, M. Esteban, Virology 1994, 199, 491-496.
20. A. E. Koromilas, S. Roy, G. N. Barber, M.G. Katze, N. Sonenberg, Science 1992, 257, 1685-1689.
21. E. F. Meurs, J. Galabru, G. N. Barber, M. G. Katze, A. G. Hovanessian, Proc. Natl. Acad. Sci. USA 1993, 90, 232-236.
22. J. O. Langland, P. N. Kao, B. L. Jacobs, Biochemistry 1999, 38, 6361-6368.
23. M. L. Jaramillo, N. Abraham, J. C. Bell, Cancer Invest. 1995, 13, 327-338.
24. T. Hermann, E. Westhof, Curr. Opin. Biotechnol. 1998, 9, 66-73.
25. D. E. Draper, J. Mol. Biol. 1999, 293, 255-270.
26. S. Cusack, Curr. Opin. Struct. Biol. 1999, 9, 66-73.
27. T. A. Steitz in The RNA World, 2nd Ed. (Eds.: R. F. Gesteland, T. R. Cech, J. F. Atkins), Cold Spring Harbor Laboratory Press, NY, 1999, pp.427-450.
28. K.A. Xavier, P. S. Eder, T. Giordano, Trends Biotechnol. 2000, 18, 349-356.
29. S. J. Sucheck, C.-W. Wong, Curr. Opin. Chem. Biol. 2000, 4, 678-686.
30. W. D. Wilson, K. Li, Curr. Med. Chem. 2000, 7, 73-98.
31. T. Herman, Angew. Chem. 2000, 112, 1962-1979; Angew. Chem. Int. Ed. 2000, 39, 1890-1905.
32. T. Herman, Angew. Chem. 2000, 112, 1962-1979; Angew. Chem. Int. Ed. 2000, 39, 1890-1905.
33. H.-Y. Mei, D. P. Mack, A. A. Galan, N. S. Halim, A. Heldsinger, J. A. Loo, D.W. Moreland, K. A. Sannes-Lowery, L. Sharmeen, H. N. Truong, A. W. Czarnik, Bioorg. Med. Chem. 1997, 5, 1173-1184.
34. F. Hamy, V. Brondani, A. Flösheimer, W. Stark, M. J. J. Blommers, T. Klimkait, Biochemistry 1998, 37, 5086-5095.
35. S. Hwang, N. Tamilarasu, K. Ryan, I. Huq, S. Richter, W. C. Still, T. M. Rana, Proc. Natl. Acad. Sci. USA 1999, 96, 12997-13002.
36. M. Vuyisich, P. A. Beal, Nucleic Acids Res. 2000, 28, 2369-2374.
37. D. P. Figgitt, W. A. Denny, S. A. Gamage, R. K. Ralph, Anticancer Drug Des. 1994. 9, 199-208.
38. G. W. Rewcastle, W. A. Denny, W. R. Wilson, B. C. Baguley, Anticancer Drug Des. 1986, 1, 215-22.
39. B. C. Baguley, G. J. Finlay, J. Natl. Cancer Inst. 1988, 80, 195-199.
40. C. Bailly, P. Colson, C. Houssier, F. Hamy, Nucleic Acids Res. 1996, 24, 1460-1464.
41. C. B. Carlson, P. A. Beal, Org. Lett. 2000, 2, 1465-1468.
42. C.B. Carlson, P.A. Beal, Bioorg. Med. Chem. Lett. 2000, 10, 1979-1982.
43. R. J. Spanggord, P. A. Beal, Biochemistry 2001, 40, 4272-4280.
44. V. M. Guelev, M. T. Harting, R. S. Lokey, B. L. Iverson, Chem. Biol. 2000, 7, 1-8.
45. T. D. Sakore, B. S. Reddy, H. M. Sobell, J. Mol. Biol. 1979, 135, 763-785.
46. S. F. Singleton, P. B. Dervan, J. Am. Chem. Soc. 1992, 114, 6957-6965.
47. R. J. Spanggord, M. Vuyisich, P. A. Beal, Biochemistry 2002, 41, 4511-4520.
48. P. C. Bevilacqua, C. X. George, C. E. Samuel, T. R. Cech, Biochemistry 1998, 37, 6303-6316.
49. A. G. Hovanessian, J. Galabru, Eur. J. Biochem. 1987, 167, 467-473.
50. K. M. Guckian, B. A. Schweitzer, R.X.-F. Ren, C.J. Sheils, D. C. Tahmassebi, E. T. Kool, J. Am. Chem. Soc. 2000, 122, 2213-2222.
51. A. Furka, F. Sebestyen, M. Asgedom, G. Dibo, Int. J. Pept. Protein Res. 1991, 37, 487-493.
52. W. C Chan, P. D. White in Fmoc Solid Phase Peptide Synthesis: A Practical Approach, (Eds.: W.C. Chan, P.D. White), University Press, Oxford, 2000, pp. 41-76.
53. J. Sambrook, E. F. Fritsch, T. Maniatis, Molecular Cloning: A Laboratory Manual, 2nd Ed., Cold Spring Harbor Laboratory Press, NY, 1989, Chap. 10.
54. P. C. Bevilacqua, T. R. Cech, Biochemistry, 1996, 35, 9983-9994.