Z-line proteins: Implications for additional functions

European Heart Journal, Supplement

Volumn 4, Issue I, 2002, Pages

  Knoll R ^a   Hoshijima, M ^a   Chien, K R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cytoskeleton; DCM; Heart failure; Z line

Indexed keywords

ALPHA ACTININ; CELL PROTEIN; LIM PROTEIN; MUSCLE PROTEIN; STRUCTURAL PROTEIN; UNCLASSIFIED DRUG; Z LINE PROTEIN;

CELL NUCLEUS; CONFERENCE PAPER; CYTOSKELETON; DISEASE SEVERITY; ETHNOLOGY; GENE MUTATION; GENETIC DISORDER; HEART DILATATION; HEART FAILURE; HUMAN; INTRACELLULAR TRANSPORT; KNOCKOUT GENE; NONHUMAN; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

EID: 0036898997     PISSN: 1520765X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1520-765X(02)90105-7     Document Type: Conference Paper

References (41)

1. Chien K, Olson E. Converging pathways for heart development and disease: CV@CSH. Cell 2002; 110: 153-62.
2. Chien KR. Genomic circuits and the integrative biology of cardiac diseases. Nature 2000; 407: 227-32.
3. Djinovic-Carugo K, Young P, Gautel M, Saraste M. Structure of the alpha-actinin rod: Molecular basis for cross-linking of actin filaments. Cell 1999; 98: 537-46.
4. Clark KA, McElhinny AS, Beckerle MC, Gregorio CC. Stritated muscle cytoarchitecture: An intricate web of form and function. Annu Rev Cell Biol 2002; 18: 637-706.
5. North KN, Yang N, Wattanasirichaigoon D, et al. A common nonsense mutation results in alpha-actinin-3 deficiency in the general population. Nat Genet 1999; 21: 353-4.
6. Fyrberg C, Ketchum A, Ball E, Fyrberg E. Characterization of lethal Drosophila melanogaster alpha-actinin mutants. Biochem Genet 1998; 36: 299-310.
7. Bach I. The LIM domain: Regulation by association. Mech Dev 2000; 91: 5-17.
8. Schmeichel KL, Beckerle MC. Molecular dissection of a LIM domain. Mol Biol Cell 1997; 8: 219-30.
9. Louis HA, Pino JD, Schmeichel KL, et al. Comparison of three members of the cysteine-rich protein family reveals functional conservation and divergent patterns of gene expression. J Biol Chem 1997; 272: 27484-91.
10. Chien KR. Stress pathways and heart failure. Cell 1999; 98: 555-8.
11. Arber S, Hunter JJ, Ross J Jr, et al. MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure. Cell 1997; 88: 393-403.
12. Richardson P, McKenna W, Bristow M, et al. Report of the 1995 World Health Organization/International Society and Federation of Cardiology Task Force on the Definition and Classification of cardiomyopathies. Circulation 1996; 93: 841-2.
13. Zolk O, Caroni P, Bohm M. Decreased expression of the cardiac LIM domain protein MLP in chronic human heart failure. Circulation 2000; 101: 2674-7.
14. Ecamot-Laubriet A, De Luca K, Vandroux D, et al. Down-regulation and nuclear relocation of MLP during the progression of right ventricular hypertrophy induced by chronic pressure overload. J Mol Cell Cardiol 2000; 32: 2385-95.
15. Ehler E, Horowits R, Zuppinger C, et al. Alterations at the intercalated disk associated with the absence of muscle lim protein. J Cell Biol 2001; 153: 763-72.
16. Muller JM, Isele U, Metzger E, et al. FHL2, a novel tissue-specific coactivator of the androgen receptor. EMBO J 2000; 19: 359-69.
17. Taniguchi Y, Furukawa T, Tun T, et al. LIM protein KyoT2 negatively regulates transcription by association with the RBP-J DNA-binding protein. Mol Cell Biol 1998; 18: 644-54.
18. Genini M, Schwalbe P, Scholl FA, et al. Subtractive cloning and characterization of DRAL, a novel LIM-domain protein down-regulated in rhabdomyosarcoma. DNA Cell Biol 1997; 16: 433-42.
19. Scholl FA, McLoughlin P, Ehler E, et al. DRAL is a p53-responsive gene whose four and a half LIM domain protein product induces apoptosis. J Cell Biol 2000; 151: 495-506.
20. Li HY, Kotaka M, Kostin S, et al. Translocation of a human focal adhesion LIM-only protein, FHL2, during myofibrillogenesis and identification of LIM2 as the principal determinants of FHL2 focal adhesion localization. Cell Motil Cytoskeleton 2001; 48: 11-23.
21. Chu PH, Bardwell WM, Gu Y, et al. FHL2 (SLIM3) is not essential for cardiac development and function. Mol Cell Biol 2000; 20: 7460-2.
22. Kong Y, Shelton JM, Rothermel B, et al. Cardiac-specific LIM protein FHL2 modifies the hypertrophic response to beta-adrenergic stimulation. Circulation 2001; 103: 2731-8.
23. Guy PM, Kenny DA, Gill GN. The PDZ domain of the LIM protein enigma binds to beta-tropomyosin. Mol Biol Cell 1999; 10: 1973-84.
24. Pashmforoush M, Pomies P, Peterson KL, et al. Adult mice deficient in actinin-associated LIM-domain protein reveal a developmental pathway for right ventricular cardiomyopathy. Nat Med 2001; 7: 591-7.
25. Kuroda S, Tokunaga C, Kiyohara Y, et al. Protein-protein interaction of zinc finger LIM domains with protein kinase C. J Biol Chem 1996; 271: 31029-32.
26. Zhou Q, Chu PH, Huang C, et al. Ablation of Cypher, a PDZ-LIM domain Z-line protein, causes a severe form of congenital myopathy. J Cell Biol 2001; 155: 605-12.
27. Durick K, Wu RY, Gill GN, Taylor SS. Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domain. J Biol Chem 1996; 271: 12691-4.
28. Wu RY, Gill GN. LIM domain recognition of a tyrosine-containing tight turn. J Biol Chem 1994; 269: 25085-90.
29. McKoy G, Protonotarios N, Crosby A, et al. Identification of a deletion in plakoglobin in arrhythmogenic right ventricular cardiomyopathy with palmoplantar keratoderma and woolly hair (Naxos disease). Lancet 2000; 355: 2119-24.
30. Faulkner G, Pallavicini A, Comelli A, et al. FATZ, a filamin-, actinin-, and telethonin-binding protein of the Z-disc of skeletal muscle. J Biol Chem 2000; 275: 41234-42.
31. Frey N, Richardson JA, Olson EN. Calsarcins, a novel family of sarcomeric calcineurin-binding proteins. Proc Natl Acad Sci USA 2000; 97: 14632-7.
32. Takada F, Vander Woude DL, Tong HQ, et al. Myozenin: An alpha-actinin- and gamma-filamin-binding protein of skeletal muscle Z lines. Proc Natl Acad Sci USA 2001; 98: 1595-600.
33. Frey N, Olson EN. Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins. J Biol Chem 2002; 277: 13998-4004.
34. Bang ML, Mudry RE, McElhinny AS, et al. Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies. J Cell Biol 2001; 153: 413-27.
35. Chu W, Bums DK, Swerlick RA, Presky DH. Identification and characterization of a novel cytokine-inducible nuclear protein from human endothelial cells. J Biol Chem 1995; 270: 10236-45.
36. Zou Y, Evans S, Chen J, et al. CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway. Development 1997; 124: 793-804.
37. Valle G, Faulkner G, De Antoni A, et al. Telethonin, a novel sarcomeric protein of heart and skeletal muscle. FEBS Lett 1997; 415: 163-8.
38. Gregorio CC, Trombitas K, Centner T, et al. The NH2 terminus of titin spans the Z-disc: Its interaction with a novel 19-kD ligand (T-cap) is required for sarcomeric integrity. J Cell Biol 1998; 143: 1013-27.
39. Mayans O, van der Ven PF, Wilm M, et al. Structural basis for activation of the titin kinase domain during myofibrillogenesis. Nature 1998; 395: 863-9.
40. Moreira ES, Wiltshire TJ, Faulkner G, et al. Limb-girdle muscular dystrophy type 2G is caused by mutations in the gene encoding the sarcomeric protein telethonin. Nat Genet 2000; 24: 163-6.
41. Furukawa T, Ono Y, Tsuchiya H, et al. Specific interaction of the potassium channel beta-subunit mink with the sarcomeric protein T-cap suggests a T-tubule-myofibril linking system. J Mol Biol 2001; 313: 775-84.